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Peptide record

TPDB11545

Antibacterial Anticancer Antifungal Antiparasitic Antiviral Toxicity standard
34 amino acids
Basic Information
3D PDB MODEL
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TPDB11545
Antibacterial Anticancer Antifungal Antiparasitic Antiviral Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP Peptipedia ACP740 _ACP240 AntiCP 2.0 iACP-DRLF AFP-GFuse Antifungipept CAFPdb ToxinPred 3.0
standard
No
A 34-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, Peptipedia, and other sources, with an available 3D structural model.
Sequence
GETFDKLKEKLKTFYQKLVEKAEDLKGDLKAKLS
Physicochemical Analysis
C180H298N44O54
RNCHIMPW
K
3942.61
9.69
9
7
12
+2
14.86
-0.918
83.24
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
1490
37.79
5
Residue Composition
number
2
A
0
R
0
N
3
D
0
C
4
E
1
Q
2
G
0
H
0
I
6
L
9
K
0
M
2
F
0
P
1
S
2
T
0
W
1
Y
1
V
Amino Acid Distribution
A: 2 R: 0 N: 0 D: 3 C: 0 E: 4 Q: 1 G: 2 H: 0 I: 0 L: 6 K: 9 M: 0 F: 2 P: 0 S: 1 T: 2 W: 0 Y: 1 V: 1
Chemical Descriptors
34
C180H298N44O54
3942.61
9.69
+2
14.86
-0.918
Evidence Records 2 records
Evidence 1 Activity

Activity

20% Hemolysis
Toxicity
>120 µM
Hemolytic Cytotoxic
20% Hemolysis | >120 | µM | target cell: Rabbit erythrocytes

Target

Rabbit erythrocytes

Source & Reference

NA
DBAASP
Latarcins, antimicrobial and cytolytic peptides from the venom of the spider Lachesana tarabaevi (Zodariidae) that exemplify biomolecular diversity. | J Biol Chem | 2006
Evidence 2 Activity

Activity

2% Hemolysis
Toxicity
256 µg/mL
Hemolytic Cytotoxic
2% Hemolysis | 256 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Membrane Interactions of Latarcins: Antimicrobial Peptides from Spider Venom | Int J Mol Sci | 2021