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Peptide record

TPDB11544

Antibacterial Anticancer Antifungal Antiparasitic standard
34 amino acids
Basic Information
3D PDB MODEL
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TPDB11544
Antibacterial Anticancer Antifungal Antiparasitic
Anti-infective peptides Cancer-related peptides
AntiBP3 pep-lab Peptipedia AntiCP 2.0 iACP-DRLF Antifungipept i2APP
standard
No
A 34-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, pep-lab, Peptipedia, and other sources, with an available 3D structural model.
Sequence
GRCVCRKQLLCSYRERRIGDCKIRGVRFPFCCPR
Physicochemical Analysis
C172H289N61O42S6
ANHMTW
R
4075.93
10.21
10
2
9
+8
7.11
-0.447
62.94
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
1865
45.76
9
Residue Composition
number
0
A
8
R
0
N
1
D
6
C
1
E
1
Q
3
G
0
H
2
I
2
L
2
K
0
M
2
F
2
P
1
S
0
T
0
W
1
Y
2
V
Amino Acid Distribution
A: 0 R: 8 N: 0 D: 1 C: 6 E: 1 Q: 1 G: 3 H: 0 I: 2 L: 2 K: 2 M: 0 F: 2 P: 2 S: 1 T: 0 W: 0 Y: 1 V: 2
Chemical Descriptors
34
C172H289N61O42S6
4075.93
10.21
+8
7.11
-0.447
Evidence Records 3 records
Evidence 1 Activity

Activity

Antibacterial

Source & Reference

NA

Other

log deduction after 20 min incubation with 50 ug/ml peptide. Active against S. aureus strains 566, 502A, J.F. (reduction 0.3-1.7 logs), S. epidermidis UCLA-622 (reduction 1.7 logs), S. pneumoniae Type III (reduction >3.5 log), S. agalactiae Type I-A or III (reduction 0.9-1.2 logs), L. monocytogenes 450 (reduction 4.3 logs), P. aeruginosa PAO579 (reduction 4.2 logs), E. coli ATCC 29648 (reduction 1.4 logs), K. pneumoniae ATCC 13883 (reduction 3.4 logs), S. marcescens (reduction 0.7 log), H. influenzae Type 3A (reduction 0.7 log), B. bronchiseptica UCLA-342 (reduction 0.1 log).
Evidence 2 Activity

Activity

Antifungal

Source & Reference

Antifungipept

Other

log deduction after 20 min incubation with 50 ug/ml peptide. Active against S. aureus strains 566, 502A, J.F. (reduction 0.3-1.7 logs), S. epidermidis UCLA-622 (reduction 1.7 logs), S. pneumoniae Type III (reduction >3.5 log), S. agalactiae Type I-A or III (reduction 0.9-1.2 logs), L. monocytogenes 450 (reduction 4.3 logs), P. aeruginosa PAO579 (reduction 4.2 logs), E. coli ATCC 29648 (reduction 1.4 logs), K. pneumoniae ATCC 13883 (reduction 3.4 logs), S. marcescens (reduction 0.7 log), H. influenzae Type 3A (reduction 0.7 log), B. bronchiseptica UCLA-342 (reduction 0.1 log).
Evidence 3 Activity

Activity

Antiparasitic

Source & Reference

NA

Other

log deduction after 20 min incubation with 50 ug/ml peptide. Active against S. aureus strains 566, 502A, J.F. (reduction 0.3-1.7 logs), S. epidermidis UCLA-622 (reduction 1.7 logs), S. pneumoniae Type III (reduction >3.5 log), S. agalactiae Type I-A or III (reduction 0.9-1.2 logs), L. monocytogenes 450 (reduction 4.3 logs), P. aeruginosa PAO579 (reduction 4.2 logs), E. coli ATCC 29648 (reduction 1.4 logs), K. pneumoniae ATCC 13883 (reduction 3.4 logs), S. marcescens (reduction 0.7 log), H. influenzae Type 3A (reduction 0.7 log), B. bronchiseptica UCLA-342 (reduction 0.1 log).