Back to search

Peptide record

TPDB11542

Antibacterial Anticancer Antifungal Antiparasitic standard
34 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB11542
Antibacterial Anticancer Antifungal Antiparasitic
Anti-infective peptides Cancer-related peptides
AntiBP3 dbAMP DRAMP Peptipedia ACP740 _ACP240 AntiCP 2.0 iACP-DRLF Antifungipept
standard
No
A 34-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
YVPLPNVPQPGRRPFPTFPGQGPFNPKIKWPQGY
Physicochemical Analysis
C187H270N48O43
ADCEHMS
P
3878.50
10.80
4
0
10
+4
3.01
-0.912
40.00
Mammalian: 2.8 hour Yeast: 10 min E.coli: 2 min
8480
218.64
8
Residue Composition
number
0
A
2
R
2
N
0
D
0
C
0
E
3
Q
4
G
0
H
1
I
1
L
2
K
0
M
3
F
10
P
0
S
1
T
1
W
2
Y
2
V
Amino Acid Distribution
A: 0 R: 2 N: 2 D: 0 C: 0 E: 0 Q: 3 G: 4 H: 0 I: 1 L: 1 K: 2 M: 0 F: 3 P: 10 S: 0 T: 1 W: 1 Y: 2 V: 2
Chemical Descriptors
34
C187H270N48O43
3878.50
10.80
+4
3.01
-0.912
Evidence Records 18 records
Evidence 1 Activity

Activity

MIC
Antibacterial
25-50 µg/mL

Target

A. tumefaciens Gembloux A

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class. DRAMP antibacterial activity supported by MIC records against bacterial target organisms.
Active against A. tumefaciens Gembloux A (MIC 25-50 ug/ml), E. salicis NCPPB 2530 (MIC 25-50 ug/ml), E. coli NCTC 9001 or NCTC 9001* or K524 (MIC 10
Evidence 2 Activity

Activity

MIC
Antibacterial
25-50 µg/mL

Target

E. salicis NCPPB 2530

Source & Reference

dbAMP DRAMP

Other

Active against A. tumefaciens Gembloux A (MIC 25-50 ug/ml), E. salicis NCPPB 2530 (MIC 25-50 ug/ml), E. coli NCTC 9001 or NCTC 9001* or K524 (MIC 10-50 ug/ml), P. syringae pv. tomamta NCPPB
Evidence 3 Activity

Activity

MIC
Antibacterial
25-50 µg/mL

Target

v. tomamta NCPPB 1105

Source & Reference

dbAMP DRAMP

Other

MIC 25-50 ug/ml), E. coli NCTC 9001 or NCTC 9001* or K524 (MIC 10-50 ug/ml), P. syringae pv. tomamta NCPPB 1105 (MIC 25-50 ug/ml), X. campestris pv. vesicatoria LMG 905 (MIC 5-10 ug/ml), and Gram-positive bacteria B. me
Evidence 4 Activity

Activity

MIC
Antibacterial
5-10 µg/mL

Target

v. vesicatoria LMG 905

Source & Reference

dbAMP DRAMP

Other

4 (MIC 10-50 ug/ml), P. syringae pv. tomamta NCPPB 1105 (MIC 25-50 ug/ml), X. campestris pv. vesicatoria LMG 905 (MIC 5-10 ug/ml), and Gram-positive bacteria B. megaterium OMB 1551 (MIC 10-25 ug/ml), B.alvei LMG 6922 (M
Evidence 5 Activity

Activity

MIC
Antibacterial
10-25 µg/mL

Target

B. megaterium OMB 1551

Source & Reference

dbAMP DRAMP

Other

g/ml), X. campestris pv. vesicatoria LMG 905 (MIC 5-10 ug/ml), and Gram-positive bacteria B. megaterium OMB 1551 (MIC 10-25 ug/ml), B.alvei LMG 6922 (MIC > 100 ug/ml), and M. luteus or M. lysodeikticus LMG 4050 (MIC 10-2
Evidence 6 Activity

Activity

MIC
Antibacterial
10-25 µg/mL

Target

M. lysodeikticus LMG 4050

Source & Reference

dbAMP DRAMP

Other

gaterium OMB 1551 (MIC 10-25 ug/ml), B.alvei LMG 6922 (MIC > 100 ug/ml), and M. luteus or M. lysodeikticus LMG 4050 (MIC 10-25 ug/ml). Thus, the highest observed specific activity of the peptide was against an apidaecin-res
Evidence 7 Activity

Activity

MIC
Antifungal
25-50 µg/mL

Target

A. tumefaciens Gembloux A

Source & Reference

dbAMP DRAMP Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class. DRAMP antifungal activity supported by activity records against fungal target organisms.
Active against A. tumefaciens Gembloux A (MIC 25-50 ug/ml), E. salicis NCPPB 2530 (MIC 25-50 ug/ml), E. coli NCTC 9001 or NCTC 9001* or K524 (MIC 10
Evidence 8 Activity

Activity

MIC
Antifungal
25-50 µg/mL

Target

E. salicis NCPPB 2530

Source & Reference

dbAMP DRAMP Antifungipept

Other

Active against A. tumefaciens Gembloux A (MIC 25-50 ug/ml), E. salicis NCPPB 2530 (MIC 25-50 ug/ml), E. coli NCTC 9001 or NCTC 9001* or K524 (MIC 10-50 ug/ml), P. syringae pv. tomamta NCPPB
Evidence 9 Activity

Activity

MIC
Antifungal
25-50 µg/mL

Target

v. tomamta NCPPB 1105

Source & Reference

dbAMP DRAMP Antifungipept

Other

MIC 25-50 ug/ml), E. coli NCTC 9001 or NCTC 9001* or K524 (MIC 10-50 ug/ml), P. syringae pv. tomamta NCPPB 1105 (MIC 25-50 ug/ml), X. campestris pv. vesicatoria LMG 905 (MIC 5-10 ug/ml), and Gram-positive bacteria B. me
Evidence 10 Activity

Activity

MIC
Antifungal
5-10 µg/mL

Target

v. vesicatoria LMG 905

Source & Reference

dbAMP DRAMP Antifungipept

Other

4 (MIC 10-50 ug/ml), P. syringae pv. tomamta NCPPB 1105 (MIC 25-50 ug/ml), X. campestris pv. vesicatoria LMG 905 (MIC 5-10 ug/ml), and Gram-positive bacteria B. megaterium OMB 1551 (MIC 10-25 ug/ml), B.alvei LMG 6922 (M
Evidence 11 Activity

Activity

MIC
Antifungal
10-25 µg/mL

Target

B. megaterium OMB 1551

Source & Reference

dbAMP DRAMP Antifungipept

Other

g/ml), X. campestris pv. vesicatoria LMG 905 (MIC 5-10 ug/ml), and Gram-positive bacteria B. megaterium OMB 1551 (MIC 10-25 ug/ml), B.alvei LMG 6922 (MIC > 100 ug/ml), and M. luteus or M. lysodeikticus LMG 4050 (MIC 10-2
Evidence 12 Activity

Activity

MIC
Antifungal
10-25 µg/mL

Target

M. lysodeikticus LMG 4050

Source & Reference

dbAMP DRAMP Antifungipept

Other

gaterium OMB 1551 (MIC 10-25 ug/ml), B.alvei LMG 6922 (MIC > 100 ug/ml), and M. luteus or M. lysodeikticus LMG 4050 (MIC 10-25 ug/ml). Thus, the highest observed specific activity of the peptide was against an apidaecin-res
Evidence 13 Activity

Activity

MIC
Antiparasitic
25-50 µg/mL

Target

A. tumefaciens Gembloux A

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiparasitic
DRAMP antiparasitic activity supported by activity records against parasitic targets.
Active against A. tumefaciens Gembloux A (MIC 25-50 ug/ml), E. salicis NCPPB 2530 (MIC 25-50 ug/ml), E. coli NCTC 9001 or NCTC 9001* or K524 (MIC 10
Evidence 14 Activity

Activity

MIC
Antiparasitic
25-50 µg/mL

Target

E. salicis NCPPB 2530

Source & Reference

DRAMP

Other

Active against A. tumefaciens Gembloux A (MIC 25-50 ug/ml), E. salicis NCPPB 2530 (MIC 25-50 ug/ml), E. coli NCTC 9001 or NCTC 9001* or K524 (MIC 10-50 ug/ml), P. syringae pv. tomamta NCPPB
Evidence 15 Activity

Activity

MIC
Antiparasitic
25-50 µg/mL

Target

v. tomamta NCPPB 1105

Source & Reference

DRAMP

Other

MIC 25-50 ug/ml), E. coli NCTC 9001 or NCTC 9001* or K524 (MIC 10-50 ug/ml), P. syringae pv. tomamta NCPPB 1105 (MIC 25-50 ug/ml), X. campestris pv. vesicatoria LMG 905 (MIC 5-10 ug/ml), and Gram-positive bacteria B. me
Evidence 16 Activity

Activity

MIC
Antiparasitic
5-10 µg/mL

Target

v. vesicatoria LMG 905

Source & Reference

DRAMP

Other

4 (MIC 10-50 ug/ml), P. syringae pv. tomamta NCPPB 1105 (MIC 25-50 ug/ml), X. campestris pv. vesicatoria LMG 905 (MIC 5-10 ug/ml), and Gram-positive bacteria B. megaterium OMB 1551 (MIC 10-25 ug/ml), B.alvei LMG 6922 (M
Evidence 17 Activity

Activity

MIC
Antiparasitic
10-25 µg/mL

Target

B. megaterium OMB 1551

Source & Reference

DRAMP

Other

g/ml), X. campestris pv. vesicatoria LMG 905 (MIC 5-10 ug/ml), and Gram-positive bacteria B. megaterium OMB 1551 (MIC 10-25 ug/ml), B.alvei LMG 6922 (MIC > 100 ug/ml), and M. luteus or M. lysodeikticus LMG 4050 (MIC 10-2
Evidence 18 Activity

Activity

MIC
Antiparasitic
10-25 µg/mL

Target

M. lysodeikticus LMG 4050

Source & Reference

DRAMP

Other

gaterium OMB 1551 (MIC 10-25 ug/ml), B.alvei LMG 6922 (MIC > 100 ug/ml), and M. luteus or M. lysodeikticus LMG 4050 (MIC 10-25 ug/ml). Thus, the highest observed specific activity of the peptide was against an apidaecin-res