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Peptide record

TPDB11536

Antibacterial Anticancer Antifungal Antiparasitic Antiviral Hemolysis Toxicity standard
34 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB11536
Antibacterial Anticancer Antifungal Antiparasitic Antiviral Hemolysis Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP pep-lab Peptipedia Antifungipept CAFPdb i2APP dbAMP 3.0 DRAVP 2.0 APD_complete HemoPI Hemolytic2 PD_Hemolysis ToxinPred 3.0
standard
No
A 34-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
ALWFTMLKKLGTMALHAGKAALGAAANTISQGTQ
Physicochemical Analysis
C155H255N43O43S2
RDCEPYV
A
3473.11
10.84
4
0
18
+3
-1.67
0.382
92.35
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
5500
158.36
8
Residue Composition
number
8
A
0
R
1
N
0
D
0
C
0
E
2
Q
4
G
1
H
1
I
5
L
3
K
2
M
1
F
0
P
1
S
4
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 8 R: 0 N: 1 D: 0 C: 0 E: 0 Q: 2 G: 4 H: 1 I: 1 L: 5 K: 3 M: 2 F: 1 P: 0 S: 1 T: 4 W: 1 Y: 0 V: 0
Chemical Descriptors
34
C155H255N43O43S2
3473.11
10.84
+3
-1.67
0.382
Evidence Records 62 records
Evidence 1 Activity

Activity

MIC
Antibacterial
1 µM

Target

A. caviae IP67-16T

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class. DRAMP antibacterial activity supported by MIC records against bacterial target organisms.
Active against A. caviae IP67-16T (MIC 1 uM), E. coli IP76-24 (MIC 2.5 uM), E. faecalis IP103214, S. aureus IP76-25 (MIC 10-20 uM), N.
Evidence 2 Activity

Activity

MIC
Antibacterial
2.5 µM

Target

Escherichia coli IP76-24

Source & Reference

dbAMP DRAMP

Other

Active against A. caviae IP67-16T (MIC 1 uM), E. coli IP76-24 (MIC 2.5 uM), E. faecalis IP103214, S. aureus IP76-25 (MIC 10-20 uM), N. brasiliensis IP118079 (MIC 20
Evidence 3 Activity

Activity

MIC
Antibacterial
10-20 µM

Target

Staphylococcus aureus IP76-25

Source & Reference

dbAMP DRAMP

Other

gainst A. caviae IP67-16T (MIC 1 uM), E. coli IP76-24 (MIC 2.5 uM), E. faecalis IP103214, S. aureus IP76-25 (MIC 10-20 uM), N. brasiliensis IP118079 (MIC 20 uM), S. cerevisiae IP118079 (MIC 5 uM), C. albicans IP8
Evidence 4 Activity

Activity

MIC
Antibacterial
20 µM

Target

N. brasiliensis IP118079

Source & Reference

dbAMP DRAMP

Other

M), E. coli IP76-24 (MIC 2.5 uM), E. faecalis IP103214, S. aureus IP76-25 (MIC 10-20 uM), N. brasiliensis IP118079 (MIC 20 uM), S. cerevisiae IP118079 (MIC 5 uM), C. albicans IP884-65, IP886-65 (MIC 5-10 uM), C. neof
Evidence 5 Activity

Activity

MIC
Antibacterial
5 µM

Target

S. cerevisiae IP118079

Source & Reference

dbAMP DRAMP

Other

aecalis IP103214, S. aureus IP76-25 (MIC 10-20 uM), N. brasiliensis IP118079 (MIC 20 uM), S. cerevisiae IP118079 (MIC 5 uM), C. albicans IP884-65, IP886-65 (MIC 5-10 uM), C. neoformans IP960-67 and IP962-67 (MIC 1
Evidence 6 Activity

Activity

MIC
Antibacterial
1 µM

Target

C. neoformans IP960-67 and IP962-67

Source & Reference

dbAMP DRAMP

Other

20 uM), S. cerevisiae IP118079 (MIC 5 uM), C. albicans IP884-65, IP886-65 (MIC 5-10 uM), C. neoformans IP960-67 and IP962-67 (MIC 1 uM), M. canis IP1194 (MIC 15 uM), T. rubrum IP2043-92 (MIC 35 uM), T. metagrophytes IP877-71
Evidence 7 Activity

Activity

MIC
Antibacterial
15 µM

Target

M. canis IP1194

Source & Reference

dbAMP DRAMP

Other

lbicans IP884-65, IP886-65 (MIC 5-10 uM), C. neoformans IP960-67 and IP962-67 (MIC 1 uM), M. canis IP1194 (MIC 15 uM), T. rubrum IP2043-92 (MIC 35 uM), T. metagrophytes IP877-71 (MIC 20 uM), A. simii IP1063-
Evidence 8 Activity

Activity

MIC
Antibacterial
35 µM

Target

T. rubrum IP2043-92

Source & Reference

dbAMP DRAMP

Other

IC 5-10 uM), C. neoformans IP960-67 and IP962-67 (MIC 1 uM), M. canis IP1194 (MIC 15 uM), T. rubrum IP2043-92 (MIC 35 uM), T. metagrophytes IP877-71 (MIC 20 uM), A. simii IP1063-74, mutant (MIC 20-30 uM), A. sim
Evidence 9 Activity

Activity

MIC
Antibacterial
20 µM

Target

T. metagrophytes IP877-71

Source & Reference

dbAMP DRAMP

Other

67 and IP962-67 (MIC 1 uM), M. canis IP1194 (MIC 15 uM), T. rubrum IP2043-92 (MIC 35 uM), T. metagrophytes IP877-71 (MIC 20 uM), A. simii IP1063-74, mutant (MIC 20-30 uM), A. simii J43 (MIC 20 uM), A. niger IP218-53 a
Evidence 10 Activity

Activity

MIC
Antibacterial
20 µM

Target

A. simii J43

Source & Reference

dbAMP DRAMP

Other

35 uM), T. metagrophytes IP877-71 (MIC 20 uM), A. simii IP1063-74, mutant (MIC 20-30 uM), A. simii J43 (MIC 20 uM), A. niger IP218-53 and A. fumigatus IP1025-70 (MIC 20 uM). Activity against M. canis (MIC
Evidence 11 Activity

Activity

MIC
Antibacterial
20 µM

Target

A. fumigatus IP1025-70

Source & Reference

dbAMP DRAMP

Other

. simii IP1063-74, mutant (MIC 20-30 uM), A. simii J43 (MIC 20 uM), A. niger IP218-53 and A. fumigatus IP1025-70 (MIC 20 uM). Activity against M. canis (MIC 10 ug/ml), T. rubrum, E. coli, C. neoformans, C. albicans
Evidence 12 Activity

Activity

MIC
Antibacterial
10 µg/mL

Target

M. canis

Source & Reference

dbAMP DRAMP

Other

3 (MIC 20 uM), A. niger IP218-53 and A. fumigatus IP1025-70 (MIC 20 uM). Activity against M. canis (MIC 10 ug/ml), T. rubrum, E. coli, C. neoformans, C. albicans (MIC 15 ug/ml), A. simii, N. brasiliensis
Evidence 13 Activity

Activity

MIC
Antibacterial
15 µg/mL

Target

Candida albicans

Source & Reference

dbAMP DRAMP

Other

(MIC 20 uM). Activity against M. canis (MIC 10 ug/ml), T. rubrum, E. coli, C. neoformans, C. albicans (MIC 15 ug/ml), A. simii, N. brasiliensis (MIC 30ug/ml) and A. caviae (MIC 30 ug/ml). It also has antivi
Evidence 14 Activity

Activity

MIC
Antibacterial
30 µg/mL

Target

N. brasiliensis

Source & Reference

dbAMP DRAMP

Other

(MIC 10 ug/ml), T. rubrum, E. coli, C. neoformans, C. albicans (MIC 15 ug/ml), A. simii, N. brasiliensis (MIC 30ug/ml) and A. caviae (MIC 30 ug/ml). It also has antiviral activity against HSV-1 (16 ug/ml). Up
Evidence 15 Activity

Activity

MIC
Antibacterial
30 µg/mL

Target

A. caviae

Source & Reference

dbAMP DRAMP

Other

i, C. neoformans, C. albicans (MIC 15 ug/ml), A. simii, N. brasiliensis (MIC 30ug/ml) and A. caviae (MIC 30 ug/ml). It also has antiviral activity against HSV-1 (16 ug/ml). Updated 4/2019 C. Wang Updated
Evidence 16 Activity

Activity

MIC
Antifungal
1 µM

Target

A. caviae IP67-16T

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class. DRAMP antifungal activity supported by activity records against fungal target organisms.
Active against A. caviae IP67-16T (MIC 1 uM), E. coli IP76-24 (MIC 2.5 uM), E. faecalis IP103214, S. aureus IP76-25 (MIC 10-20 uM), N.
Evidence 17 Activity

Activity

MIC
Antifungal
2.5 µM

Target

Escherichia coli IP76-24

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Active against A. caviae IP67-16T (MIC 1 uM), E. coli IP76-24 (MIC 2.5 uM), E. faecalis IP103214, S. aureus IP76-25 (MIC 10-20 uM), N. brasiliensis IP118079 (MIC 20
Evidence 18 Activity

Activity

MIC
Antifungal
10-20 µM

Target

Staphylococcus aureus IP76-25

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

gainst A. caviae IP67-16T (MIC 1 uM), E. coli IP76-24 (MIC 2.5 uM), E. faecalis IP103214, S. aureus IP76-25 (MIC 10-20 uM), N. brasiliensis IP118079 (MIC 20 uM), S. cerevisiae IP118079 (MIC 5 uM), C. albicans IP8
Evidence 19 Activity

Activity

MIC
Antifungal
20 µM

Target

N. brasiliensis IP118079

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

M), E. coli IP76-24 (MIC 2.5 uM), E. faecalis IP103214, S. aureus IP76-25 (MIC 10-20 uM), N. brasiliensis IP118079 (MIC 20 uM), S. cerevisiae IP118079 (MIC 5 uM), C. albicans IP884-65, IP886-65 (MIC 5-10 uM), C. neof
Evidence 20 Activity

Activity

MIC
Antifungal
5 µM

Target

S. cerevisiae IP118079

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

aecalis IP103214, S. aureus IP76-25 (MIC 10-20 uM), N. brasiliensis IP118079 (MIC 20 uM), S. cerevisiae IP118079 (MIC 5 uM), C. albicans IP884-65, IP886-65 (MIC 5-10 uM), C. neoformans IP960-67 and IP962-67 (MIC 1
Evidence 21 Activity

Activity

MIC
Antifungal
1 µM

Target

C. neoformans IP960-67 and IP962-67

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

20 uM), S. cerevisiae IP118079 (MIC 5 uM), C. albicans IP884-65, IP886-65 (MIC 5-10 uM), C. neoformans IP960-67 and IP962-67 (MIC 1 uM), M. canis IP1194 (MIC 15 uM), T. rubrum IP2043-92 (MIC 35 uM), T. metagrophytes IP877-71
Evidence 22 Activity

Activity

MIC
Antifungal
15 µM

Target

M. canis IP1194

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

lbicans IP884-65, IP886-65 (MIC 5-10 uM), C. neoformans IP960-67 and IP962-67 (MIC 1 uM), M. canis IP1194 (MIC 15 uM), T. rubrum IP2043-92 (MIC 35 uM), T. metagrophytes IP877-71 (MIC 20 uM), A. simii IP1063-
Evidence 23 Activity

Activity

MIC
Antifungal
35 µM

Target

T. rubrum IP2043-92

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

IC 5-10 uM), C. neoformans IP960-67 and IP962-67 (MIC 1 uM), M. canis IP1194 (MIC 15 uM), T. rubrum IP2043-92 (MIC 35 uM), T. metagrophytes IP877-71 (MIC 20 uM), A. simii IP1063-74, mutant (MIC 20-30 uM), A. sim
Evidence 24 Activity

Activity

MIC
Antifungal
20 µM

Target

T. metagrophytes IP877-71

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

67 and IP962-67 (MIC 1 uM), M. canis IP1194 (MIC 15 uM), T. rubrum IP2043-92 (MIC 35 uM), T. metagrophytes IP877-71 (MIC 20 uM), A. simii IP1063-74, mutant (MIC 20-30 uM), A. simii J43 (MIC 20 uM), A. niger IP218-53 a
Evidence 25 Activity

Activity

MIC
Antifungal
20 µM

Target

A. simii J43

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

35 uM), T. metagrophytes IP877-71 (MIC 20 uM), A. simii IP1063-74, mutant (MIC 20-30 uM), A. simii J43 (MIC 20 uM), A. niger IP218-53 and A. fumigatus IP1025-70 (MIC 20 uM). Activity against M. canis (MIC
Evidence 26 Activity

Activity

MIC
Antifungal
20 µM

Target

A. fumigatus IP1025-70

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

. simii IP1063-74, mutant (MIC 20-30 uM), A. simii J43 (MIC 20 uM), A. niger IP218-53 and A. fumigatus IP1025-70 (MIC 20 uM). Activity against M. canis (MIC 10 ug/ml), T. rubrum, E. coli, C. neoformans, C. albicans
Evidence 27 Activity

Activity

MIC
Antifungal
10 µg/mL

Target

M. canis

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

3 (MIC 20 uM), A. niger IP218-53 and A. fumigatus IP1025-70 (MIC 20 uM). Activity against M. canis (MIC 10 ug/ml), T. rubrum, E. coli, C. neoformans, C. albicans (MIC 15 ug/ml), A. simii, N. brasiliensis
Evidence 28 Activity

Activity

MIC
Antifungal
15 µg/mL

Target

Candida albicans

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

(MIC 20 uM). Activity against M. canis (MIC 10 ug/ml), T. rubrum, E. coli, C. neoformans, C. albicans (MIC 15 ug/ml), A. simii, N. brasiliensis (MIC 30ug/ml) and A. caviae (MIC 30 ug/ml). It also has antivi
Evidence 29 Activity

Activity

MIC
Antifungal
30 µg/mL

Target

N. brasiliensis

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

(MIC 10 ug/ml), T. rubrum, E. coli, C. neoformans, C. albicans (MIC 15 ug/ml), A. simii, N. brasiliensis (MIC 30ug/ml) and A. caviae (MIC 30 ug/ml). It also has antiviral activity against HSV-1 (16 ug/ml). Up
Evidence 30 Activity

Activity

MIC
Antifungal
30 µg/mL

Target

A. caviae

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

i, C. neoformans, C. albicans (MIC 15 ug/ml), A. simii, N. brasiliensis (MIC 30ug/ml) and A. caviae (MIC 30 ug/ml). It also has antiviral activity against HSV-1 (16 ug/ml). Updated 4/2019 C. Wang Updated
Evidence 31 Activity

Activity

MIC
Antiparasitic
1 µM

Target

A. caviae IP67-16T

Source & Reference

dbAMP 3.0 DRAMP

Other

Source Activity Label Source Definition
Antiparasitic
DRAMP antiparasitic activity supported by activity records against parasitic targets. dbAMP 3.0 classified under the Anti-parasitic function class.
Active against A. caviae IP67-16T (MIC 1 uM), E. coli IP76-24 (MIC 2.5 uM), E. faecalis IP103214, S. aureus IP76-25 (MIC 10-20 uM), N.
Evidence 32 Activity

Activity

MIC
Antiparasitic
2.5 µM

Target

Escherichia coli IP76-24

Source & Reference

dbAMP 3.0 DRAMP

Other

Active against A. caviae IP67-16T (MIC 1 uM), E. coli IP76-24 (MIC 2.5 uM), E. faecalis IP103214, S. aureus IP76-25 (MIC 10-20 uM), N. brasiliensis IP118079 (MIC 20
Evidence 33 Activity

Activity

MIC
Antiparasitic
10-20 µM

Target

Staphylococcus aureus IP76-25

Source & Reference

dbAMP 3.0 DRAMP

Other

gainst A. caviae IP67-16T (MIC 1 uM), E. coli IP76-24 (MIC 2.5 uM), E. faecalis IP103214, S. aureus IP76-25 (MIC 10-20 uM), N. brasiliensis IP118079 (MIC 20 uM), S. cerevisiae IP118079 (MIC 5 uM), C. albicans IP8
Evidence 34 Activity

Activity

MIC
Antiparasitic
20 µM

Target

N. brasiliensis IP118079

Source & Reference

dbAMP 3.0 DRAMP

Other

M), E. coli IP76-24 (MIC 2.5 uM), E. faecalis IP103214, S. aureus IP76-25 (MIC 10-20 uM), N. brasiliensis IP118079 (MIC 20 uM), S. cerevisiae IP118079 (MIC 5 uM), C. albicans IP884-65, IP886-65 (MIC 5-10 uM), C. neof
Evidence 35 Activity

Activity

MIC
Antiparasitic
5 µM

Target

S. cerevisiae IP118079

Source & Reference

dbAMP 3.0 DRAMP

Other

aecalis IP103214, S. aureus IP76-25 (MIC 10-20 uM), N. brasiliensis IP118079 (MIC 20 uM), S. cerevisiae IP118079 (MIC 5 uM), C. albicans IP884-65, IP886-65 (MIC 5-10 uM), C. neoformans IP960-67 and IP962-67 (MIC 1
Evidence 36 Activity

Activity

MIC
Antiparasitic
1 µM

Target

C. neoformans IP960-67 and IP962-67

Source & Reference

dbAMP 3.0 DRAMP

Other

20 uM), S. cerevisiae IP118079 (MIC 5 uM), C. albicans IP884-65, IP886-65 (MIC 5-10 uM), C. neoformans IP960-67 and IP962-67 (MIC 1 uM), M. canis IP1194 (MIC 15 uM), T. rubrum IP2043-92 (MIC 35 uM), T. metagrophytes IP877-71
Evidence 37 Activity

Activity

MIC
Antiparasitic
15 µM

Target

M. canis IP1194

Source & Reference

dbAMP 3.0 DRAMP

Other

lbicans IP884-65, IP886-65 (MIC 5-10 uM), C. neoformans IP960-67 and IP962-67 (MIC 1 uM), M. canis IP1194 (MIC 15 uM), T. rubrum IP2043-92 (MIC 35 uM), T. metagrophytes IP877-71 (MIC 20 uM), A. simii IP1063-
Evidence 38 Activity

Activity

MIC
Antiparasitic
35 µM

Target

T. rubrum IP2043-92

Source & Reference

dbAMP 3.0 DRAMP

Other

IC 5-10 uM), C. neoformans IP960-67 and IP962-67 (MIC 1 uM), M. canis IP1194 (MIC 15 uM), T. rubrum IP2043-92 (MIC 35 uM), T. metagrophytes IP877-71 (MIC 20 uM), A. simii IP1063-74, mutant (MIC 20-30 uM), A. sim
Evidence 39 Activity

Activity

MIC
Antiparasitic
20 µM

Target

T. metagrophytes IP877-71

Source & Reference

dbAMP 3.0 DRAMP

Other

67 and IP962-67 (MIC 1 uM), M. canis IP1194 (MIC 15 uM), T. rubrum IP2043-92 (MIC 35 uM), T. metagrophytes IP877-71 (MIC 20 uM), A. simii IP1063-74, mutant (MIC 20-30 uM), A. simii J43 (MIC 20 uM), A. niger IP218-53 a
Evidence 40 Activity

Activity

MIC
Antiparasitic
20 µM

Target

A. simii J43

Source & Reference

dbAMP 3.0 DRAMP

Other

35 uM), T. metagrophytes IP877-71 (MIC 20 uM), A. simii IP1063-74, mutant (MIC 20-30 uM), A. simii J43 (MIC 20 uM), A. niger IP218-53 and A. fumigatus IP1025-70 (MIC 20 uM). Activity against M. canis (MIC
Evidence 41 Activity

Activity

MIC
Antiparasitic
20 µM

Target

A. fumigatus IP1025-70

Source & Reference

dbAMP 3.0 DRAMP

Other

. simii IP1063-74, mutant (MIC 20-30 uM), A. simii J43 (MIC 20 uM), A. niger IP218-53 and A. fumigatus IP1025-70 (MIC 20 uM). Activity against M. canis (MIC 10 ug/ml), T. rubrum, E. coli, C. neoformans, C. albicans
Evidence 42 Activity

Activity

MIC
Antiparasitic
10 µg/mL

Target

M. canis

Source & Reference

dbAMP 3.0 DRAMP

Other

3 (MIC 20 uM), A. niger IP218-53 and A. fumigatus IP1025-70 (MIC 20 uM). Activity against M. canis (MIC 10 ug/ml), T. rubrum, E. coli, C. neoformans, C. albicans (MIC 15 ug/ml), A. simii, N. brasiliensis
Evidence 43 Activity

Activity

MIC
Antiparasitic
15 µg/mL

Target

Candida albicans

Source & Reference

dbAMP 3.0 DRAMP

Other

(MIC 20 uM). Activity against M. canis (MIC 10 ug/ml), T. rubrum, E. coli, C. neoformans, C. albicans (MIC 15 ug/ml), A. simii, N. brasiliensis (MIC 30ug/ml) and A. caviae (MIC 30 ug/ml). It also has antivi
Evidence 44 Activity

Activity

MIC
Antiparasitic
30 µg/mL

Target

N. brasiliensis

Source & Reference

dbAMP 3.0 DRAMP

Other

(MIC 10 ug/ml), T. rubrum, E. coli, C. neoformans, C. albicans (MIC 15 ug/ml), A. simii, N. brasiliensis (MIC 30ug/ml) and A. caviae (MIC 30 ug/ml). It also has antiviral activity against HSV-1 (16 ug/ml). Up
Evidence 45 Activity

Activity

MIC
Antiparasitic
30 µg/mL

Target

A. caviae

Source & Reference

dbAMP 3.0 DRAMP

Other

i, C. neoformans, C. albicans (MIC 15 ug/ml), A. simii, N. brasiliensis (MIC 30ug/ml) and A. caviae (MIC 30 ug/ml). It also has antiviral activity against HSV-1 (16 ug/ml). Updated 4/2019 C. Wang Updated
Evidence 46 Activity

Activity

MIC
Antiviral
1 µM

Target

A. caviae IP67-16T

Source & Reference

dbAMP 3.0 DRAMP DRAVP 2.0

Other

Source Activity Label Source Definition
Antiviral
DRAMP antiviral activity supported by activity records against viral targets. dbAMP 3.0 classified under the Anti-viral function class.
Active against A. caviae IP67-16T (MIC 1 uM), E. coli IP76-24 (MIC 2.5 uM), E. faecalis IP103214, S. aureus IP76-25 (MIC 10-20 uM), N.
Evidence 47 Activity

Activity

MIC
Antiviral
2.5 µM

Target

Escherichia coli IP76-24

Source & Reference

dbAMP 3.0 DRAMP DRAVP 2.0

Other

Active against A. caviae IP67-16T (MIC 1 uM), E. coli IP76-24 (MIC 2.5 uM), E. faecalis IP103214, S. aureus IP76-25 (MIC 10-20 uM), N. brasiliensis IP118079 (MIC 20
Evidence 48 Activity

Activity

MIC
Antiviral
10-20 µM

Target

Staphylococcus aureus IP76-25

Source & Reference

dbAMP 3.0 DRAMP DRAVP 2.0

Other

gainst A. caviae IP67-16T (MIC 1 uM), E. coli IP76-24 (MIC 2.5 uM), E. faecalis IP103214, S. aureus IP76-25 (MIC 10-20 uM), N. brasiliensis IP118079 (MIC 20 uM), S. cerevisiae IP118079 (MIC 5 uM), C. albicans IP8
Evidence 49 Activity

Activity

MIC
Antiviral
20 µM

Target

N. brasiliensis IP118079

Source & Reference

dbAMP 3.0 DRAMP DRAVP 2.0

Other

M), E. coli IP76-24 (MIC 2.5 uM), E. faecalis IP103214, S. aureus IP76-25 (MIC 10-20 uM), N. brasiliensis IP118079 (MIC 20 uM), S. cerevisiae IP118079 (MIC 5 uM), C. albicans IP884-65, IP886-65 (MIC 5-10 uM), C. neof
Evidence 50 Activity

Activity

MIC
Antiviral
5 µM

Target

S. cerevisiae IP118079

Source & Reference

dbAMP 3.0 DRAMP DRAVP 2.0

Other

aecalis IP103214, S. aureus IP76-25 (MIC 10-20 uM), N. brasiliensis IP118079 (MIC 20 uM), S. cerevisiae IP118079 (MIC 5 uM), C. albicans IP884-65, IP886-65 (MIC 5-10 uM), C. neoformans IP960-67 and IP962-67 (MIC 1
Evidence 51 Activity

Activity

MIC
Antiviral
1 µM

Target

C. neoformans IP960-67 and IP962-67

Source & Reference

dbAMP 3.0 DRAMP DRAVP 2.0

Other

20 uM), S. cerevisiae IP118079 (MIC 5 uM), C. albicans IP884-65, IP886-65 (MIC 5-10 uM), C. neoformans IP960-67 and IP962-67 (MIC 1 uM), M. canis IP1194 (MIC 15 uM), T. rubrum IP2043-92 (MIC 35 uM), T. metagrophytes IP877-71
Evidence 52 Activity

Activity

MIC
Antiviral
15 µM

Target

M. canis IP1194

Source & Reference

dbAMP 3.0 DRAMP DRAVP 2.0

Other

lbicans IP884-65, IP886-65 (MIC 5-10 uM), C. neoformans IP960-67 and IP962-67 (MIC 1 uM), M. canis IP1194 (MIC 15 uM), T. rubrum IP2043-92 (MIC 35 uM), T. metagrophytes IP877-71 (MIC 20 uM), A. simii IP1063-
Evidence 53 Activity

Activity

MIC
Antiviral
35 µM

Target

T. rubrum IP2043-92

Source & Reference

dbAMP 3.0 DRAMP DRAVP 2.0

Other

IC 5-10 uM), C. neoformans IP960-67 and IP962-67 (MIC 1 uM), M. canis IP1194 (MIC 15 uM), T. rubrum IP2043-92 (MIC 35 uM), T. metagrophytes IP877-71 (MIC 20 uM), A. simii IP1063-74, mutant (MIC 20-30 uM), A. sim
Evidence 54 Activity

Activity

MIC
Antiviral
20 µM

Target

T. metagrophytes IP877-71

Source & Reference

dbAMP 3.0 DRAMP DRAVP 2.0

Other

67 and IP962-67 (MIC 1 uM), M. canis IP1194 (MIC 15 uM), T. rubrum IP2043-92 (MIC 35 uM), T. metagrophytes IP877-71 (MIC 20 uM), A. simii IP1063-74, mutant (MIC 20-30 uM), A. simii J43 (MIC 20 uM), A. niger IP218-53 a
Evidence 55 Activity

Activity

MIC
Antiviral
20 µM

Target

A. simii J43

Source & Reference

dbAMP 3.0 DRAMP DRAVP 2.0

Other

35 uM), T. metagrophytes IP877-71 (MIC 20 uM), A. simii IP1063-74, mutant (MIC 20-30 uM), A. simii J43 (MIC 20 uM), A. niger IP218-53 and A. fumigatus IP1025-70 (MIC 20 uM). Activity against M. canis (MIC
Evidence 56 Activity

Activity

MIC
Antiviral
20 µM

Target

A. fumigatus IP1025-70

Source & Reference

dbAMP 3.0 DRAMP DRAVP 2.0

Other

. simii IP1063-74, mutant (MIC 20-30 uM), A. simii J43 (MIC 20 uM), A. niger IP218-53 and A. fumigatus IP1025-70 (MIC 20 uM). Activity against M. canis (MIC 10 ug/ml), T. rubrum, E. coli, C. neoformans, C. albicans
Evidence 57 Activity

Activity

MIC
Antiviral
10 µg/mL

Target

M. canis

Source & Reference

dbAMP 3.0 DRAMP DRAVP 2.0

Other

3 (MIC 20 uM), A. niger IP218-53 and A. fumigatus IP1025-70 (MIC 20 uM). Activity against M. canis (MIC 10 ug/ml), T. rubrum, E. coli, C. neoformans, C. albicans (MIC 15 ug/ml), A. simii, N. brasiliensis
Evidence 58 Activity

Activity

MIC
Antiviral
15 µg/mL

Target

Candida albicans

Source & Reference

dbAMP 3.0 DRAMP DRAVP 2.0

Other

(MIC 20 uM). Activity against M. canis (MIC 10 ug/ml), T. rubrum, E. coli, C. neoformans, C. albicans (MIC 15 ug/ml), A. simii, N. brasiliensis (MIC 30ug/ml) and A. caviae (MIC 30 ug/ml). It also has antivi
Evidence 59 Activity

Activity

MIC
Antiviral
30 µg/mL

Target

N. brasiliensis

Source & Reference

dbAMP 3.0 DRAMP DRAVP 2.0

Other

(MIC 10 ug/ml), T. rubrum, E. coli, C. neoformans, C. albicans (MIC 15 ug/ml), A. simii, N. brasiliensis (MIC 30ug/ml) and A. caviae (MIC 30 ug/ml). It also has antiviral activity against HSV-1 (16 ug/ml). Up
Evidence 60 Activity

Activity

MIC
Antiviral
30 µg/mL

Target

A. caviae

Source & Reference

dbAMP 3.0 DRAMP DRAVP 2.0

Other

i, C. neoformans, C. albicans (MIC 15 ug/ml), A. simii, N. brasiliensis (MIC 30ug/ml) and A. caviae (MIC 30 ug/ml). It also has antiviral activity against HSV-1 (16 ug/ml). Updated 4/2019 C. Wang Updated
Evidence 61 Activity

Activity

100% Hemolysis
Toxicity
70 µM
Hemolytic Cytotoxic
100% Hemolysis | 70 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
The vertebrate peptide antibiotics dermaseptins have overlapping structural features but target specific microorganisms. | J Biol Chem | 1994
Evidence 62 Hemolysis

Source & Reference

APD_complete HemoPI PD_Hemolysis
APD_complete PD_Hemolysis

Other

Source Activity Label Source Definition
Hemolysis
APD_complete APD-derived hemolytic peptide annotation.