Back to search

Peptide record

TPDB11515

Antibacterial Toxicity standard
34 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB11515
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 34-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
GAALAGLAKILCLWAKEFTGAFKKLNKKFAMKKK
Physicochemical Analysis
C176H291N45O39S2
RDQHPSYV
K
3725.64
10.82
9
1
18
+8
1.51
0.118
89.41
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
5500
147.63
3
Residue Composition
number
7
A
0
R
1
N
0
D
1
C
1
E
0
Q
3
G
0
H
1
I
5
L
9
K
1
M
3
F
0
P
0
S
1
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 7 R: 0 N: 1 D: 0 C: 1 E: 1 Q: 0 G: 3 H: 0 I: 1 L: 5 K: 9 M: 1 F: 3 P: 0 S: 0 T: 1 W: 1 Y: 0 V: 0
Chemical Descriptors
34
C176H291N45O39S2
3725.64
10.82
+8
1.51
0.118
Evidence Records 2 records
Evidence 1 Activity

Activity

MIC
Antibacterial
50 µM

Target

Staphylococcus aureus ATCC 25923

Source & Reference

NA

Other

active against E-coli ATCC 25922 (MIC >50 uM) and S. aureus ATCC 25923 (MIC 50 uM). Warning: other bacteria not tested.
Evidence 2 Activity

Activity

100% Hemolysis
Toxicity
50 µM
Hemolytic Cytotoxic
100% Hemolysis | 50 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
An engineered arginine-rich ?-helical antimicrobial peptide exhibits broad-spectrum bactericidal activity against pathogenic bacteria and reduces bacterial infections in mice. | Sci Rep | 2018