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Peptide record

TPDB11511

Antibacterial Antifungal Antiparasitic Toxicity standard
34 amino acids
Basic Information
3D PDB MODEL
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TPDB11511
Antibacterial Antifungal Antiparasitic Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia Antifungipept CAFPdb dbAMP dbAMP 3.0 i2APP ToxinPred 3.0
standard
No
A 34-aa standard natural multi-activity (Antibacterial, Antifungal, Antiparasitic, and other sources) peptide sequence curated from AntiBP3, Peptipedia, Antifungipept, and other sources, with an available 3D structural model.
Sequence
SPFVDRPRRPIQHNGPKPRIITNPPFNPNARPAW
Physicochemical Analysis
C179H276N58O44
CELMY
P
3944.52
12.58
7
1
9
+5
8.51
-1.203
48.82
Mammalian: 1.9 hour Yeast: >20 hour E.coli: >10 hour
5500
139.43
7
Residue Composition
number
2
A
5
R
4
N
1
D
0
C
0
E
1
Q
1
G
1
H
3
I
0
L
1
K
0
M
2
F
9
P
1
S
1
T
1
W
0
Y
1
V
Amino Acid Distribution
A: 2 R: 5 N: 4 D: 1 C: 0 E: 0 Q: 1 G: 1 H: 1 I: 3 L: 0 K: 1 M: 0 F: 2 P: 9 S: 1 T: 1 W: 1 Y: 0 V: 1
Chemical Descriptors
34
C179H276N58O44
3944.52
12.58
+5
8.51
-1.203
Evidence Records 5 records
Evidence 1 Activity

Activity

Antibacterial

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
It exhibited inhibitory activity against the blood-stage P. falciparum parasite. 7/2021
Evidence 2 Activity

Activity

Antifungal

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
It exhibited inhibitory activity against the blood-stage P. falciparum parasite. 7/2021
Evidence 3 Activity

Activity

Antiparasitic

Source & Reference

dbAMP 3.0

Other

Source Activity Label Source Definition
Antiparasitic
dbAMP 3.0 classified under the Anti-parasitic function class.
It exhibited inhibitory activity against the blood-stage P. falciparum parasite. 7/2021
Evidence 4 Activity

Activity

<10% Hemolysis
Toxicity
100 µM
Hemolytic Cytotoxic
<10% Hemolysis | 100 | µM | target cell: Mouse erythrocytes

Target

Mouse erythrocytes

Source & Reference

NA
DBAASP
The Drosophila melanogaster antimicrobial peptides Mtk-1 and Mtk-2 are active against the malarial parasite Plasmodium falciparum. | Parasitol Res | 2019
Evidence 5 Activity

Activity

<5% Hemolysis
Toxicity
100 µM
Hemolytic Cytotoxic
<5% Hemolysis | 100 | µM | target cell: Pig erythrocytes

Target

Pig erythrocytes

Source & Reference

NA
DBAASP
The Drosophila melanogaster antimicrobial peptides Mtk-1 and Mtk-2 are active against the malarial parasite Plasmodium falciparum. | Parasitol Res | 2019