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Peptide record

TPDB11498

Antibacterial Toxicity standard
34 amino acids
Basic Information
3D PDB MODEL
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TPDB11498
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 dbAMP Peptipedia
standard
No
A 34-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3, dbAMP, and Peptipedia, with an available 3D structural model.
Sequence
KKKKKKKKKKGIGKLFLHAAKKFAKAFVAEKMNS
Physicochemical Analysis
C182H316N52O39S1
RDCQPTWY
K
3888.90
11.32
16
1
13
+14
12.57
-1.021
57.65
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
0
0.00
2
Residue Composition
number
5
A
0
R
1
N
0
D
0
C
1
E
0
Q
2
G
1
H
1
I
2
L
15
K
1
M
3
F
0
P
1
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 5 R: 0 N: 1 D: 0 C: 0 E: 1 Q: 0 G: 2 H: 1 I: 1 L: 2 K: 15 M: 1 F: 3 P: 0 S: 1 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
34
C182H316N52O39S1
3888.90
11.32
+14
12.57
-1.021
Evidence Records 1 records
Evidence 1 Activity

Activity

2% Hemolysis
Toxicity
200 µg/mL
Hemolytic Cytotoxic
2% Hemolysis | 200 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Augmentation of the antibacterial activity of magainin by positive-charge chain extension. | Antimicrob Agents Chemother | 1992