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Peptide record

TPDB11489

Antibacterial Anticancer Antifungal Antiparasitic standard
33 amino acids
Basic Information
3D PDB MODEL
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TPDB11489
Antibacterial Anticancer Antifungal Antiparasitic
Anti-infective peptides Cancer-related peptides
AntiBP3 pep-lab Peptipedia Antifungipept
standard
No
A 33-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, pep-lab, Peptipedia, and other sources, with an available 3D structural model.
Sequence
VFCTCRGFLCGSGERASGSCTINGVRHTLCCRR
Physicochemical Analysis
C143H237N51O43S6
DQKMPWY
C
3551.13
8.61
6
1
8
+4
3.15
0.112
56.06
Mammalian: 100 hour Yeast: >20 hour E.coli: >10 hour
375
10.56
13
Residue Composition
number
1
A
5
R
1
N
0
D
6
C
1
E
0
Q
5
G
1
H
1
I
2
L
0
K
0
M
2
F
0
P
3
S
3
T
0
W
0
Y
2
V
Amino Acid Distribution
A: 1 R: 5 N: 1 D: 0 C: 6 E: 1 Q: 0 G: 5 H: 1 I: 1 L: 2 K: 0 M: 0 F: 2 P: 0 S: 3 T: 3 W: 0 Y: 0 V: 2
Chemical Descriptors
33
C143H237N51O43S6
3551.13
8.61
+4
3.15
0.112
Evidence Records 3 records
Evidence 1 Activity

Activity

Antibacterial

Source & Reference

NA

Other

log deduction after 20 min incubation with 50 ug/ml peptide. Active against S. aureus strains 566, 502A, J.F. (reduction 0.1-0.4 logs), S. epidermidis UCLA-622 (reduction 0.4 logs), S. pneumoniae Type III (reduction 1.9 log), S. agalactiae Type I-A or III (reduction 0.4-0.5 logs), L. monocytogenes 450 (reduction 0.2 logs), P. aeruginosa PAO579 (reduction 0.7 logs), E. coli ATCC 29648 (reduction 0.2 logs), K. pneumoniae ATCC 13883 (reduction 1.2 logs), S. marcescens (reduction 0.2 log), H. influenzae Type 3A (reduction 1.2 log), B.bronchiseptica UCLA-342 (reduction 0.0 log).
Evidence 2 Activity

Activity

Antifungal

Source & Reference

Antifungipept

Other

log deduction after 20 min incubation with 50 ug/ml peptide. Active against S. aureus strains 566, 502A, J.F. (reduction 0.1-0.4 logs), S. epidermidis UCLA-622 (reduction 0.4 logs), S. pneumoniae Type III (reduction 1.9 log), S. agalactiae Type I-A or III (reduction 0.4-0.5 logs), L. monocytogenes 450 (reduction 0.2 logs), P. aeruginosa PAO579 (reduction 0.7 logs), E. coli ATCC 29648 (reduction 0.2 logs), K. pneumoniae ATCC 13883 (reduction 1.2 logs), S. marcescens (reduction 0.2 log), H. influenzae Type 3A (reduction 1.2 log), B.bronchiseptica UCLA-342 (reduction 0.0 log).
Evidence 3 Activity

Activity

Antiparasitic

Source & Reference

NA

Other

log deduction after 20 min incubation with 50 ug/ml peptide. Active against S. aureus strains 566, 502A, J.F. (reduction 0.1-0.4 logs), S. epidermidis UCLA-622 (reduction 0.4 logs), S. pneumoniae Type III (reduction 1.9 log), S. agalactiae Type I-A or III (reduction 0.4-0.5 logs), L. monocytogenes 450 (reduction 0.2 logs), P. aeruginosa PAO579 (reduction 0.7 logs), E. coli ATCC 29648 (reduction 0.2 logs), K. pneumoniae ATCC 13883 (reduction 1.2 logs), S. marcescens (reduction 0.2 log), H. influenzae Type 3A (reduction 1.2 log), B.bronchiseptica UCLA-342 (reduction 0.0 log).