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Peptide record

TPDB11486

Antibacterial Antifungal Toxicity standard
33 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB11486
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia Antifungipept CAFPdb dbAMP ToxinPred 3.0
standard
No
A 33-aa standard natural multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, Antifungipept, and other sources, with an available 3D structural model.
Sequence
SIRDKIKTMAIDLAKSAGTGVLKTLICKLDKSC
Physicochemical Analysis
C152H274N42O46S3
NEQHFPWY
K
3522.28
9.98
7
3
13
+4
6.64
0.182
112.42
Mammalian: 1.9 hour Yeast: >20 hour E.coli: >10 hour
125
3.55
8
Residue Composition
number
3
A
1
R
0
N
3
D
2
C
0
E
0
Q
2
G
0
H
4
I
4
L
6
K
1
M
0
F
0
P
3
S
3
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 3 R: 1 N: 0 D: 3 C: 2 E: 0 Q: 0 G: 2 H: 0 I: 4 L: 4 K: 6 M: 1 F: 0 P: 0 S: 3 T: 3 W: 0 Y: 0 V: 1
Chemical Descriptors
33
C152H274N42O46S3
3522.28
9.98
+4
6.64
0.182
Evidence Records 13 records
Evidence 1 Activity

Activity

MIC
Antibacterial
10 µg/mL

Target

Staphylococcus aureus ATCC2592

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
>: Active against S. aureus ATCC2592 (MIC 10 ug/ml), S. aureus ATCC43300 (MRSA) (MIC 15 ug/ml), B. subtilis (MIC 40 ug/ml), E. coli ML-35P (M
Evidence 2 Activity

Activity

MIC
Antibacterial
40 µg/mL

Target

B. subtilis

Source & Reference

dbAMP

Other

ive against S. aureus ATCC2592 (MIC 10 ug/ml), S. aureus ATCC43300 (MRSA) (MIC 15 ug/ml), B. subtilis (MIC 40 ug/ml), E. coli ML-35P (MIC 10 ug/ml), P. aeruginosa PA01 (MIC 5 ug/ml), P. aeruginosa ATCC27853
Evidence 3 Activity

Activity

MIC
Antibacterial
10 µg/mL

Target

Escherichia coli ML-35P

Source & Reference

dbAMP

Other

92 (MIC 10 ug/ml), S. aureus ATCC43300 (MRSA) (MIC 15 ug/ml), B. subtilis (MIC 40 ug/ml), E. coli ML-35P (MIC 10 ug/ml), P. aeruginosa PA01 (MIC 5 ug/ml), P. aeruginosa ATCC27853 (MIC 5 ug/ml), and C. albicans
Evidence 4 Activity

Activity

MIC
Antibacterial
5 µg/mL

Target

Pseudomonas aeruginosa PA01

Source & Reference

dbAMP

Other

CC43300 (MRSA) (MIC 15 ug/ml), B. subtilis (MIC 40 ug/ml), E. coli ML-35P (MIC 10 ug/ml), P. aeruginosa PA01 (MIC 5 ug/ml), P. aeruginosa ATCC27853 (MIC 5 ug/ml), and C. albicans ATCC2002 (MIC 10 ug/ml).
Evidence 5 Activity

Activity

MIC
Antibacterial
5 µg/mL

Target

Pseudomonas aeruginosa ATCC27853

Source & Reference

dbAMP

Other

subtilis (MIC 40 ug/ml), E. coli ML-35P (MIC 10 ug/ml), P. aeruginosa PA01 (MIC 5 ug/ml), P. aeruginosa ATCC27853 (MIC 5 ug/ml), and C. albicans ATCC2002 (MIC 10 ug/ml).
Evidence 6 Activity

Activity

MIC
Antibacterial
10 µg/mL

Target

Candida albicans ATCC2002

Source & Reference

dbAMP

Other

C 10 ug/ml), P. aeruginosa PA01 (MIC 5 ug/ml), P. aeruginosa ATCC27853 (MIC 5 ug/ml), and C. albicans ATCC2002 (MIC 10 ug/ml).
Evidence 7 Activity

Activity

MIC
Antifungal
10 µg/mL

Target

Staphylococcus aureus ATCC2592

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
>: Active against S. aureus ATCC2592 (MIC 10 ug/ml), S. aureus ATCC43300 (MRSA) (MIC 15 ug/ml), B. subtilis (MIC 40 ug/ml), E. coli ML-35P (M
Evidence 8 Activity

Activity

MIC
Antifungal
40 µg/mL

Target

B. subtilis

Source & Reference

dbAMP CAFPdb Antifungipept

Other

ive against S. aureus ATCC2592 (MIC 10 ug/ml), S. aureus ATCC43300 (MRSA) (MIC 15 ug/ml), B. subtilis (MIC 40 ug/ml), E. coli ML-35P (MIC 10 ug/ml), P. aeruginosa PA01 (MIC 5 ug/ml), P. aeruginosa ATCC27853
Evidence 9 Activity

Activity

MIC
Antifungal
10 µg/mL

Target

Escherichia coli ML-35P

Source & Reference

dbAMP CAFPdb Antifungipept

Other

92 (MIC 10 ug/ml), S. aureus ATCC43300 (MRSA) (MIC 15 ug/ml), B. subtilis (MIC 40 ug/ml), E. coli ML-35P (MIC 10 ug/ml), P. aeruginosa PA01 (MIC 5 ug/ml), P. aeruginosa ATCC27853 (MIC 5 ug/ml), and C. albicans
Evidence 10 Activity

Activity

MIC
Antifungal
5 µg/mL

Target

Pseudomonas aeruginosa PA01

Source & Reference

dbAMP CAFPdb Antifungipept

Other

CC43300 (MRSA) (MIC 15 ug/ml), B. subtilis (MIC 40 ug/ml), E. coli ML-35P (MIC 10 ug/ml), P. aeruginosa PA01 (MIC 5 ug/ml), P. aeruginosa ATCC27853 (MIC 5 ug/ml), and C. albicans ATCC2002 (MIC 10 ug/ml).
Evidence 11 Activity

Activity

MIC
Antifungal
5 µg/mL

Target

Pseudomonas aeruginosa ATCC27853

Source & Reference

dbAMP CAFPdb Antifungipept

Other

subtilis (MIC 40 ug/ml), E. coli ML-35P (MIC 10 ug/ml), P. aeruginosa PA01 (MIC 5 ug/ml), P. aeruginosa ATCC27853 (MIC 5 ug/ml), and C. albicans ATCC2002 (MIC 10 ug/ml).
Evidence 12 Activity

Activity

MIC
Antifungal
10 µg/mL

Target

Candida albicans ATCC2002

Source & Reference

dbAMP CAFPdb Antifungipept

Other

C 10 ug/ml), P. aeruginosa PA01 (MIC 5 ug/ml), P. aeruginosa ATCC27853 (MIC 5 ug/ml), and C. albicans ATCC2002 (MIC 10 ug/ml).
Evidence 13 Activity

Activity

4% Hemolysis
Toxicity
100 µg/mL
Hemolytic Cytotoxic
4% Hemolysis | 100 | µg/mL | target cell: Rabbit erythrocytes

Target

Rabbit erythrocytes

Source & Reference

NA
DBAASP
Five novel antimicrobial peptides from the Kuhl's wart frog skin secretions, Limnonectes kuhlii. | Mol Biol Rep | 2013