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Peptide record

TPDB11481

Antibacterial Anticancer Antifungal Antiparasitic Toxicity standard
33 amino acids
Basic Information
3D PDB MODEL
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TPDB11481
Antibacterial Anticancer Antifungal Antiparasitic Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia Antifungipept CAFPdb ToxinPred 3.0
standard
No
A 33-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
GILDTLKEFGKTAAKGIAQSLLSTASCKLAKTC
Physicochemical Analysis
C147H255N39O46S2
RNHMPWYV
ALK
3369.00
9.65
5
2
13
+3
3.88
0.255
97.88
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
125
3.71
10
Residue Composition
number
5
A
0
R
0
N
1
D
2
C
1
E
1
Q
3
G
0
H
2
I
5
L
5
K
0
M
1
F
0
P
3
S
4
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 5 R: 0 N: 0 D: 1 C: 2 E: 1 Q: 1 G: 3 H: 0 I: 2 L: 5 K: 5 M: 0 F: 1 P: 0 S: 3 T: 4 W: 0 Y: 0 V: 0
Chemical Descriptors
33
C147H255N39O46S2
3369.00
9.65
+3
3.88
0.255
Evidence Records 5 records
Evidence 1 Activity

Activity

Antibacterial

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
Active against S. aureus ATCC2592, R. rhodochrous (Gram-poistive) and P. faecalis X29 (Gram-).
Evidence 2 Activity

Activity

Antifungal

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
Active against S. aureus ATCC2592, R. rhodochrous (Gram-poistive) and P. faecalis X29 (Gram-).
Evidence 3 Activity

Activity

Antiparasitic

Source & Reference

DRAMP

Other

Active against S. aureus ATCC2592, R. rhodochrous (Gram-poistive) and P. faecalis X29 (Gram-).
Evidence 4 Activity

Activity

Toxicity
Hemolytic Cytotoxic
- | NA | target cell: Rabbit erythrocytes

Target

Rabbit erythrocytes

Source & Reference

NA
DBAASP
Identification and characterization of antimicrobial peptides from skin of Amolops ricketti (Anura: Ranidae). | Peptides | 2012
Evidence 5 Activity

Activity

LD50
Toxicity
400 µg/mL
Hemolytic
Hemolytic_activity: [Ref.22100518]LD50>400 µg/ml against rabbit red blood cells

Target

erythrocytes

Source & Reference

NA
DRAMP
Peptides. 2012 Jan 33(1):27-34.