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Peptide record

TPDB11479

Antibacterial Anticancer Antifungal Antiparasitic Antiviral standard
33 amino acids
Basic Information
3D PDB MODEL
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TPDB11479
Antibacterial Anticancer Antifungal Antiparasitic Antiviral
Anti-infective peptides Cancer-related peptides
AntiBP3 dbAMP DRAMP Peptipedia ACP740 _ACP240 AntiCP 2.0 iACP-DRLF Antifungipept dbAMP 3.0 i2APP
standard
No
A 33-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
AANFGPSVFTPEVHETWQKFLNVVVAALGKQYH
Physicochemical Analysis
C173H254N44O46
RDCIM
V
3686.19
7.88
4
2
16
+0
3.64
0.018
79.70
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
6990
189.63
8
Residue Composition
number
4
A
0
R
2
N
0
D
0
C
2
E
2
Q
2
G
2
H
0
I
2
L
2
K
0
M
3
F
2
P
1
S
2
T
1
W
1
Y
5
V
Amino Acid Distribution
A: 4 R: 0 N: 2 D: 0 C: 0 E: 2 Q: 2 G: 2 H: 2 I: 0 L: 2 K: 2 M: 0 F: 3 P: 2 S: 1 T: 2 W: 1 Y: 1 V: 5
Chemical Descriptors
33
C173H254N44O46
3686.19
7.88
+0
3.64
0.018
Evidence Records 12 records
Evidence 1 Activity

Activity

MIC
Antibacterial
3.4 µM

Target

Escherichia coli D31

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class. DRAMP antibacterial activity supported by MIC records against bacterial target organisms.
This AMP showed moderate activity against Gram-negative bacteria such as E. coli D31 (MIC 3.4 uM), A. hydrophila (MIC 3.4 uM) and V. alginolyticus 88-5009-A2 (MIC 13.5 uM), but no activit
Evidence 2 Activity

Activity

MIC
Antibacterial
3.4 µM

Target

A. hydrophila

Source & Reference

dbAMP DRAMP

Other

showed moderate activity against Gram-negative bacteria such as E. coli D31 (MIC 3.4 uM), A. hydrophila (MIC 3.4 uM) and V. alginolyticus 88-5009-A2 (MIC 13.5 uM), but no activity against Gram-positive bact
Evidence 3 Activity

Activity

MIC
Antibacterial
13.5 µM

Target

V. alginolyticus 88-5009-A2

Source & Reference

dbAMP DRAMP

Other

t Gram-negative bacteria such as E. coli D31 (MIC 3.4 uM), A. hydrophila (MIC 3.4 uM) and V. alginolyticus 88-5009-A2 (MIC 13.5 uM), but no activity against Gram-positive bacteria such as S.aureus, S.faecalis, S.iniae, Gr
Evidence 4 Activity

Activity

MIC
Antifungal
3.4 µM

Target

Escherichia coli D31

Source & Reference

dbAMP DRAMP Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class. DRAMP antifungal activity supported by activity records against fungal target organisms.
This AMP showed moderate activity against Gram-negative bacteria such as E. coli D31 (MIC 3.4 uM), A. hydrophila (MIC 3.4 uM) and V. alginolyticus 88-5009-A2 (MIC 13.5 uM), but no activit
Evidence 5 Activity

Activity

MIC
Antifungal
3.4 µM

Target

A. hydrophila

Source & Reference

dbAMP DRAMP Antifungipept

Other

showed moderate activity against Gram-negative bacteria such as E. coli D31 (MIC 3.4 uM), A. hydrophila (MIC 3.4 uM) and V. alginolyticus 88-5009-A2 (MIC 13.5 uM), but no activity against Gram-positive bact
Evidence 6 Activity

Activity

MIC
Antifungal
13.5 µM

Target

V. alginolyticus 88-5009-A2

Source & Reference

dbAMP DRAMP Antifungipept

Other

t Gram-negative bacteria such as E. coli D31 (MIC 3.4 uM), A. hydrophila (MIC 3.4 uM) and V. alginolyticus 88-5009-A2 (MIC 13.5 uM), but no activity against Gram-positive bacteria such as S.aureus, S.faecalis, S.iniae, Gr
Evidence 7 Activity

Activity

MIC
Antiparasitic
3.4 µM

Target

Escherichia coli D31

Source & Reference

dbAMP 3.0 DRAMP

Other

Source Activity Label Source Definition
Antiparasitic
DRAMP antiparasitic activity supported by activity records against parasitic targets. dbAMP 3.0 classified under the Anti-parasitic function class.
This AMP showed moderate activity against Gram-negative bacteria such as E. coli D31 (MIC 3.4 uM), A. hydrophila (MIC 3.4 uM) and V. alginolyticus 88-5009-A2 (MIC 13.5 uM), but no activit
Evidence 8 Activity

Activity

MIC
Antiparasitic
3.4 µM

Target

A. hydrophila

Source & Reference

dbAMP 3.0 DRAMP

Other

showed moderate activity against Gram-negative bacteria such as E. coli D31 (MIC 3.4 uM), A. hydrophila (MIC 3.4 uM) and V. alginolyticus 88-5009-A2 (MIC 13.5 uM), but no activity against Gram-positive bact
Evidence 9 Activity

Activity

MIC
Antiparasitic
13.5 µM

Target

V. alginolyticus 88-5009-A2

Source & Reference

dbAMP 3.0 DRAMP

Other

t Gram-negative bacteria such as E. coli D31 (MIC 3.4 uM), A. hydrophila (MIC 3.4 uM) and V. alginolyticus 88-5009-A2 (MIC 13.5 uM), but no activity against Gram-positive bacteria such as S.aureus, S.faecalis, S.iniae, Gr
Evidence 10 Activity

Activity

MIC
Antiviral
3.4 µM

Target

Escherichia coli D31

Source & Reference

dbAMP 3.0 DRAMP

Other

Source Activity Label Source Definition
Antiviral
DRAMP antiviral activity supported by activity records against viral targets. dbAMP 3.0 classified under the Anti-viral function class.
This AMP showed moderate activity against Gram-negative bacteria such as E. coli D31 (MIC 3.4 uM), A. hydrophila (MIC 3.4 uM) and V. alginolyticus 88-5009-A2 (MIC 13.5 uM), but no activit
Evidence 11 Activity

Activity

MIC
Antiviral
3.4 µM

Target

A. hydrophila

Source & Reference

dbAMP 3.0 DRAMP

Other

showed moderate activity against Gram-negative bacteria such as E. coli D31 (MIC 3.4 uM), A. hydrophila (MIC 3.4 uM) and V. alginolyticus 88-5009-A2 (MIC 13.5 uM), but no activity against Gram-positive bact
Evidence 12 Activity

Activity

MIC
Antiviral
13.5 µM

Target

V. alginolyticus 88-5009-A2

Source & Reference

dbAMP 3.0 DRAMP

Other

t Gram-negative bacteria such as E. coli D31 (MIC 3.4 uM), A. hydrophila (MIC 3.4 uM) and V. alginolyticus 88-5009-A2 (MIC 13.5 uM), but no activity against Gram-positive bacteria such as S.aureus, S.faecalis, S.iniae, Gr