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Peptide record

TPDB11476

Antibacterial Anticancer Antifungal Antiparasitic Antiviral standard
33 amino acids
Basic Information
3D PDB MODEL
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TPDB11476
Antibacterial Anticancer Antifungal Antiparasitic Antiviral
Anti-infective peptides Cancer-related peptides
AntiBP3 dbAMP DRAMP Peptipedia Antifungipept CAFPdb
standard
No
A 33-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
SFLTTFKDLAIKAAKSAGQSVLSTLSCKLSNTC
Physicochemical Analysis
C150H253N39O48S2
REHMPWY
S
3435.01
9.72
4
1
13
+3
1.08
0.345
91.82
Mammalian: 1.9 hour Yeast: >20 hour E.coli: >10 hour
125
3.64
14
Residue Composition
number
4
A
0
R
1
N
1
D
2
C
0
E
1
Q
1
G
0
H
1
I
5
L
4
K
0
M
2
F
0
P
6
S
4
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 4 R: 0 N: 1 D: 1 C: 2 E: 0 Q: 1 G: 1 H: 0 I: 1 L: 5 K: 4 M: 0 F: 2 P: 0 S: 6 T: 4 W: 0 Y: 0 V: 1
Chemical Descriptors
33
C150H253N39O48S2
3435.01
9.72
+3
1.08
0.345
Evidence Records 20 records
Evidence 1 Activity

Activity

MIC
Antibacterial
12.5 µM

Target

Escherichia coli

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class. DRAMP antibacterial activity supported by MIC records against bacterial target organisms.
Active against E. coli (MIC 12.5 uM), S. aureus (MIC 6.3 uM), S.aureus MRSA-inactive (MIC >100 uM), B. subtilis (MIC 25 uM), a
Evidence 2 Activity

Activity

MIC
Antibacterial
6.3 µM

Target

Staphylococcus aureus

Source & Reference

dbAMP DRAMP

Other

Active against E. coli (MIC 12.5 uM), S. aureus (MIC 6.3 uM), S.aureus MRSA-inactive (MIC >100 uM), B. subtilis (MIC 25 uM), and C.albicans (MIC >100
Evidence 3 Activity

Activity

MIC
Antibacterial
>100 µM

Target

S.aureus MRSA-inactive

Source & Reference

dbAMP DRAMP

Other

Active against E. coli (MIC 12.5 uM), S. aureus (MIC 6.3 uM), S.aureus MRSA-inactive (MIC >100 uM), B. subtilis (MIC 25 uM), and C.albicans (MIC >100 uM).
Evidence 4 Activity

Activity

MIC
Antibacterial
25 µM

Target

B. subtilis

Source & Reference

dbAMP DRAMP

Other

inst E. coli (MIC 12.5 uM), S. aureus (MIC 6.3 uM), S.aureus MRSA-inactive (MIC >100 uM), B. subtilis (MIC 25 uM), and C.albicans (MIC >100 uM).
Evidence 5 Activity

Activity

MIC
Antibacterial
>100 µM

Target

C.albicans

Source & Reference

dbAMP DRAMP

Other

. aureus (MIC 6.3 uM), S.aureus MRSA-inactive (MIC >100 uM), B. subtilis (MIC 25 uM), and C.albicans (MIC >100 uM).
Evidence 6 Activity

Activity

MIC
Antifungal
12.5 µM

Target

Escherichia coli

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class. DRAMP antifungal activity supported by activity records against fungal target organisms.
Active against E. coli (MIC 12.5 uM), S. aureus (MIC 6.3 uM), S.aureus MRSA-inactive (MIC >100 uM), B. subtilis (MIC 25 uM), a
Evidence 7 Activity

Activity

MIC
Antifungal
6.3 µM

Target

Staphylococcus aureus

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Active against E. coli (MIC 12.5 uM), S. aureus (MIC 6.3 uM), S.aureus MRSA-inactive (MIC >100 uM), B. subtilis (MIC 25 uM), and C.albicans (MIC >100
Evidence 8 Activity

Activity

MIC
Antifungal
>100 µM

Target

S.aureus MRSA-inactive

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Active against E. coli (MIC 12.5 uM), S. aureus (MIC 6.3 uM), S.aureus MRSA-inactive (MIC >100 uM), B. subtilis (MIC 25 uM), and C.albicans (MIC >100 uM).
Evidence 9 Activity

Activity

MIC
Antifungal
25 µM

Target

B. subtilis

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

inst E. coli (MIC 12.5 uM), S. aureus (MIC 6.3 uM), S.aureus MRSA-inactive (MIC >100 uM), B. subtilis (MIC 25 uM), and C.albicans (MIC >100 uM).
Evidence 10 Activity

Activity

MIC
Antifungal
>100 µM

Target

C.albicans

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

. aureus (MIC 6.3 uM), S.aureus MRSA-inactive (MIC >100 uM), B. subtilis (MIC 25 uM), and C.albicans (MIC >100 uM).
Evidence 11 Activity

Activity

MIC
Antiparasitic
12.5 µM

Target

Escherichia coli

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiparasitic
DRAMP antiparasitic activity supported by activity records against parasitic targets.
Active against E. coli (MIC 12.5 uM), S. aureus (MIC 6.3 uM), S.aureus MRSA-inactive (MIC >100 uM), B. subtilis (MIC 25 uM), a
Evidence 12 Activity

Activity

MIC
Antiparasitic
6.3 µM

Target

Staphylococcus aureus

Source & Reference

DRAMP

Other

Active against E. coli (MIC 12.5 uM), S. aureus (MIC 6.3 uM), S.aureus MRSA-inactive (MIC >100 uM), B. subtilis (MIC 25 uM), and C.albicans (MIC >100
Evidence 13 Activity

Activity

MIC
Antiparasitic
>100 µM

Target

S.aureus MRSA-inactive

Source & Reference

DRAMP

Other

Active against E. coli (MIC 12.5 uM), S. aureus (MIC 6.3 uM), S.aureus MRSA-inactive (MIC >100 uM), B. subtilis (MIC 25 uM), and C.albicans (MIC >100 uM).
Evidence 14 Activity

Activity

MIC
Antiparasitic
25 µM

Target

B. subtilis

Source & Reference

DRAMP

Other

inst E. coli (MIC 12.5 uM), S. aureus (MIC 6.3 uM), S.aureus MRSA-inactive (MIC >100 uM), B. subtilis (MIC 25 uM), and C.albicans (MIC >100 uM).
Evidence 15 Activity

Activity

MIC
Antiparasitic
>100 µM

Target

C.albicans

Source & Reference

DRAMP

Other

. aureus (MIC 6.3 uM), S.aureus MRSA-inactive (MIC >100 uM), B. subtilis (MIC 25 uM), and C.albicans (MIC >100 uM).
Evidence 16 Activity

Activity

MIC
Antiviral
12.5 µM

Target

Escherichia coli

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiviral
DRAMP antiviral activity supported by activity records against viral targets.
Active against E. coli (MIC 12.5 uM), S. aureus (MIC 6.3 uM), S.aureus MRSA-inactive (MIC >100 uM), B. subtilis (MIC 25 uM), a
Evidence 17 Activity

Activity

MIC
Antiviral
6.3 µM

Target

Staphylococcus aureus

Source & Reference

DRAMP

Other

Active against E. coli (MIC 12.5 uM), S. aureus (MIC 6.3 uM), S.aureus MRSA-inactive (MIC >100 uM), B. subtilis (MIC 25 uM), and C.albicans (MIC >100
Evidence 18 Activity

Activity

MIC
Antiviral
>100 µM

Target

S.aureus MRSA-inactive

Source & Reference

DRAMP

Other

Active against E. coli (MIC 12.5 uM), S. aureus (MIC 6.3 uM), S.aureus MRSA-inactive (MIC >100 uM), B. subtilis (MIC 25 uM), and C.albicans (MIC >100 uM).
Evidence 19 Activity

Activity

MIC
Antiviral
25 µM

Target

B. subtilis

Source & Reference

DRAMP

Other

inst E. coli (MIC 12.5 uM), S. aureus (MIC 6.3 uM), S.aureus MRSA-inactive (MIC >100 uM), B. subtilis (MIC 25 uM), and C.albicans (MIC >100 uM).
Evidence 20 Activity

Activity

MIC
Antiviral
>100 µM

Target

C.albicans

Source & Reference

DRAMP

Other

. aureus (MIC 6.3 uM), S.aureus MRSA-inactive (MIC >100 uM), B. subtilis (MIC 25 uM), and C.albicans (MIC >100 uM).