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Peptide record

TPDB11475

Antibacterial Anticancer Antifungal Antiparasitic Antiviral Toxicity standard
33 amino acids
Basic Information
3D PDB MODEL
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TPDB11475
Antibacterial Anticancer Antifungal Antiparasitic Antiviral Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP Peptipedia AFP-GFuse Antifungipept CAFPdb ToxinPred 3.0
standard
No
A 33-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, Peptipedia, and other sources, with an available 3D structural model.
Sequence
QAFQTFKPDWNKIRYDAMKMQTSLGQMKKRFNL
Physicochemical Analysis
C182H285N51O48S3
CEHV
K
4051.76
10.75
7
2
13
+5
4.42
-1.003
41.52
Mammalian: 0.8 hour Yeast: 10 min E.coli: >10 hour
6990
172.52
10
Residue Composition
number
2
A
2
R
2
N
2
D
0
C
0
E
4
Q
1
G
0
H
1
I
2
L
5
K
3
M
3
F
1
P
1
S
2
T
1
W
1
Y
0
V
Amino Acid Distribution
A: 2 R: 2 N: 2 D: 2 C: 0 E: 0 Q: 4 G: 1 H: 0 I: 1 L: 2 K: 5 M: 3 F: 3 P: 1 S: 1 T: 2 W: 1 Y: 1 V: 0
Chemical Descriptors
33
C182H285N51O48S3
4051.76
10.75
+5
4.42
-1.003
Evidence Records 2 records
Evidence 1 Activity

Activity

20% Hemolysis
Toxicity
>120 µM
Hemolytic Cytotoxic
20% Hemolysis | >120 | µM | target cell: Rabbit erythrocytes

Target

Rabbit erythrocytes

Source & Reference

NA
DBAASP
Latarcins, antimicrobial and cytolytic peptides from the venom of the spider Lachesana tarabaevi (Zodariidae) that exemplify biomolecular diversity. | J Biol Chem | 2006
Evidence 2 Activity

Activity

3% Hemolysis
Toxicity
256 µg/mL
Hemolytic Cytotoxic
3% Hemolysis | 256 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Membrane Interactions of Latarcins: Antimicrobial Peptides from Spider Venom | Int J Mol Sci | 2021