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Peptide record

TPDB11469

Antibacterial Anticancer Antifungal Antiparasitic Antiviral standard
33 amino acids
Basic Information
3D PDB MODEL
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TPDB11469
Antibacterial Anticancer Antifungal Antiparasitic Antiviral
Anti-infective peptides Cancer-related peptides
AntiBP3 dbAMP DRAMP Peptipedia Antifungipept CAFPdb
standard
No
A 33-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
SVLGTVKDLLIGAGKSAAQSVLTALSCKLSNSC
Physicochemical Analysis
C138H244N38O46S2
REHMFPWY
LS
3235.80
9.08
3
1
14
+2
1.67
0.682
121.21
Mammalian: 1.9 hour Yeast: >20 hour E.coli: >10 hour
125
3.86
12
Residue Composition
number
4
A
0
R
1
N
1
D
2
C
0
E
1
Q
3
G
0
H
1
I
6
L
3
K
0
M
0
F
0
P
6
S
2
T
0
W
0
Y
3
V
Amino Acid Distribution
A: 4 R: 0 N: 1 D: 1 C: 2 E: 0 Q: 1 G: 3 H: 0 I: 1 L: 6 K: 3 M: 0 F: 0 P: 0 S: 6 T: 2 W: 0 Y: 0 V: 3
Chemical Descriptors
33
C138H244N38O46S2
3235.80
9.08
+2
1.67
0.682
Evidence Records 12 records
Evidence 1 Activity

Activity

MIC
Antibacterial
5.5 µg/mL

Target

Escherichia coli

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class. DRAMP antibacterial activity supported by MIC records against bacterial target organisms.
Active against Gram- bacteria E. coli (MIC 5.5 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 22.0 ug/ml), Gram+ bacteria S. aureus (MIC
Evidence 2 Activity

Activity

MIC
Antibacterial
11 µg/mL

Target

Staphylococcus aureus

Source & Reference

dbAMP DRAMP

Other

MIC 5.5 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 22.0 ug/ml), Gram+ bacteria S. aureus (MIC 11 ug/ml), and yeast C. albicans (MIC 11.0 ug/ml). Found in multiple species. Also see Yang X et al
Evidence 3 Activity

Activity

MIC
Antibacterial
11.0 µg/mL

Target

Candida albicans

Source & Reference

dbAMP DRAMP

Other

alled P. aeruginosa) (MIC 22.0 ug/ml), Gram+ bacteria S. aureus (MIC 11 ug/ml), and yeast C. albicans (MIC 11.0 ug/ml). Found in multiple species. Also see Yang X et al. 2012 J Proteome Res. J Proteome Res. 1
Evidence 4 Activity

Activity

MIC
Antifungal
5.5 µg/mL

Target

Escherichia coli

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class. DRAMP antifungal activity supported by activity records against fungal target organisms.
Active against Gram- bacteria E. coli (MIC 5.5 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 22.0 ug/ml), Gram+ bacteria S. aureus (MIC
Evidence 5 Activity

Activity

MIC
Antifungal
11 µg/mL

Target

Staphylococcus aureus

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

MIC 5.5 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 22.0 ug/ml), Gram+ bacteria S. aureus (MIC 11 ug/ml), and yeast C. albicans (MIC 11.0 ug/ml). Found in multiple species. Also see Yang X et al
Evidence 6 Activity

Activity

MIC
Antifungal
11.0 µg/mL

Target

Candida albicans

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

alled P. aeruginosa) (MIC 22.0 ug/ml), Gram+ bacteria S. aureus (MIC 11 ug/ml), and yeast C. albicans (MIC 11.0 ug/ml). Found in multiple species. Also see Yang X et al. 2012 J Proteome Res. J Proteome Res. 1
Evidence 7 Activity

Activity

MIC
Antiparasitic
5.5 µg/mL

Target

Escherichia coli

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiparasitic
DRAMP antiparasitic activity supported by activity records against parasitic targets.
Active against Gram- bacteria E. coli (MIC 5.5 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 22.0 ug/ml), Gram+ bacteria S. aureus (MIC
Evidence 8 Activity

Activity

MIC
Antiparasitic
11 µg/mL

Target

Staphylococcus aureus

Source & Reference

DRAMP

Other

MIC 5.5 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 22.0 ug/ml), Gram+ bacteria S. aureus (MIC 11 ug/ml), and yeast C. albicans (MIC 11.0 ug/ml). Found in multiple species. Also see Yang X et al
Evidence 9 Activity

Activity

MIC
Antiparasitic
11.0 µg/mL

Target

Candida albicans

Source & Reference

DRAMP

Other

alled P. aeruginosa) (MIC 22.0 ug/ml), Gram+ bacteria S. aureus (MIC 11 ug/ml), and yeast C. albicans (MIC 11.0 ug/ml). Found in multiple species. Also see Yang X et al. 2012 J Proteome Res. J Proteome Res. 1
Evidence 10 Activity

Activity

MIC
Antiviral
5.5 µg/mL

Target

Escherichia coli

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiviral
DRAMP antiviral activity supported by activity records against viral targets.
Active against Gram- bacteria E. coli (MIC 5.5 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 22.0 ug/ml), Gram+ bacteria S. aureus (MIC
Evidence 11 Activity

Activity

MIC
Antiviral
11 µg/mL

Target

Staphylococcus aureus

Source & Reference

DRAMP

Other

MIC 5.5 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 22.0 ug/ml), Gram+ bacteria S. aureus (MIC 11 ug/ml), and yeast C. albicans (MIC 11.0 ug/ml). Found in multiple species. Also see Yang X et al
Evidence 12 Activity

Activity

MIC
Antiviral
11.0 µg/mL

Target

Candida albicans

Source & Reference

DRAMP

Other

alled P. aeruginosa) (MIC 22.0 ug/ml), Gram+ bacteria S. aureus (MIC 11 ug/ml), and yeast C. albicans (MIC 11.0 ug/ml). Found in multiple species. Also see Yang X et al. 2012 J Proteome Res. J Proteome Res. 1