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Peptide record

TPDB11466

Antibacterial Anticancer Antifungal Antiparasitic Antiviral standard
33 amino acids
Basic Information
3D PDB MODEL
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TPDB11466
Antibacterial Anticancer Antifungal Antiparasitic Antiviral
Anti-infective peptides Cancer-related peptides
AntiBP3 dbAMP DRAMP Peptipedia AntiCP 2.0 iACP-DRLF Antifungipept CAFPdb
standard
No
A 33-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
GVLGTVKDLLIGAGKSAAQSTLKTLSCKISNDC
Physicochemical Analysis
C140H247N39O47S2
REHMFPWY
L
3292.85
9.05
4
2
12
+2
4.13
0.312
109.39
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
125
3.80
11
Residue Composition
number
3
A
0
R
1
N
2
D
2
C
0
E
1
Q
4
G
0
H
2
I
5
L
4
K
0
M
0
F
0
P
4
S
3
T
0
W
0
Y
2
V
Amino Acid Distribution
A: 3 R: 0 N: 1 D: 2 C: 2 E: 0 Q: 1 G: 4 H: 0 I: 2 L: 5 K: 4 M: 0 F: 0 P: 0 S: 4 T: 3 W: 0 Y: 0 V: 2
Chemical Descriptors
33
C140H247N39O47S2
3292.85
9.05
+2
4.13
0.312
Evidence Records 12 records
Evidence 1 Activity

Activity

MIC
Antibacterial
5.8 µg/mL

Target

Escherichia coli

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class. DRAMP antibacterial activity supported by MIC records against bacterial target organisms.
Active against Gram- bacteria E. coli (MIC 5.8 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 23.2 ug/ml), Gram+ bacteria S. aureus (MIC
Evidence 2 Activity

Activity

MIC
Antibacterial
11.6 µg/mL

Target

Staphylococcus aureus

Source & Reference

dbAMP DRAMP

Other

MIC 5.8 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 23.2 ug/ml), Gram+ bacteria S. aureus (MIC 11.6 ug/ml), and yeast C. albicans (MIC 5.8 ug/ml). Updated 7/2021
Evidence 3 Activity

Activity

MIC
Antibacterial
5.8 µg/mL

Target

Candida albicans

Source & Reference

dbAMP DRAMP

Other

led P. aeruginosa) (MIC 23.2 ug/ml), Gram+ bacteria S. aureus (MIC 11.6 ug/ml), and yeast C. albicans (MIC 5.8 ug/ml). Updated 7/2021
Evidence 4 Activity

Activity

MIC
Antifungal
5.8 µg/mL

Target

Escherichia coli

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class. DRAMP antifungal activity supported by activity records against fungal target organisms.
Active against Gram- bacteria E. coli (MIC 5.8 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 23.2 ug/ml), Gram+ bacteria S. aureus (MIC
Evidence 5 Activity

Activity

MIC
Antifungal
11.6 µg/mL

Target

Staphylococcus aureus

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

MIC 5.8 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 23.2 ug/ml), Gram+ bacteria S. aureus (MIC 11.6 ug/ml), and yeast C. albicans (MIC 5.8 ug/ml). Updated 7/2021
Evidence 6 Activity

Activity

MIC
Antifungal
5.8 µg/mL

Target

Candida albicans

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

led P. aeruginosa) (MIC 23.2 ug/ml), Gram+ bacteria S. aureus (MIC 11.6 ug/ml), and yeast C. albicans (MIC 5.8 ug/ml). Updated 7/2021
Evidence 7 Activity

Activity

MIC
Antiparasitic
5.8 µg/mL

Target

Escherichia coli

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiparasitic
DRAMP antiparasitic activity supported by activity records against parasitic targets.
Active against Gram- bacteria E. coli (MIC 5.8 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 23.2 ug/ml), Gram+ bacteria S. aureus (MIC
Evidence 8 Activity

Activity

MIC
Antiparasitic
11.6 µg/mL

Target

Staphylococcus aureus

Source & Reference

DRAMP

Other

MIC 5.8 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 23.2 ug/ml), Gram+ bacteria S. aureus (MIC 11.6 ug/ml), and yeast C. albicans (MIC 5.8 ug/ml). Updated 7/2021
Evidence 9 Activity

Activity

MIC
Antiparasitic
5.8 µg/mL

Target

Candida albicans

Source & Reference

DRAMP

Other

led P. aeruginosa) (MIC 23.2 ug/ml), Gram+ bacteria S. aureus (MIC 11.6 ug/ml), and yeast C. albicans (MIC 5.8 ug/ml). Updated 7/2021
Evidence 10 Activity

Activity

MIC
Antiviral
5.8 µg/mL

Target

Escherichia coli

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiviral
DRAMP antiviral activity supported by activity records against viral targets.
Active against Gram- bacteria E. coli (MIC 5.8 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 23.2 ug/ml), Gram+ bacteria S. aureus (MIC
Evidence 11 Activity

Activity

MIC
Antiviral
11.6 µg/mL

Target

Staphylococcus aureus

Source & Reference

DRAMP

Other

MIC 5.8 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 23.2 ug/ml), Gram+ bacteria S. aureus (MIC 11.6 ug/ml), and yeast C. albicans (MIC 5.8 ug/ml). Updated 7/2021
Evidence 12 Activity

Activity

MIC
Antiviral
5.8 µg/mL

Target

Candida albicans

Source & Reference

DRAMP

Other

led P. aeruginosa) (MIC 23.2 ug/ml), Gram+ bacteria S. aureus (MIC 11.6 ug/ml), and yeast C. albicans (MIC 5.8 ug/ml). Updated 7/2021