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Peptide record

TPDB11465

Antibacterial Anticancer Antifungal Antiparasitic Antiviral standard
33 amino acids
Basic Information
3D PDB MODEL
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TPDB11465
Antibacterial Anticancer Antifungal Antiparasitic Antiviral
Anti-infective peptides Cancer-related peptides
AntiBP3 dbAMP DRAMP Peptipedia Antifungipept CAFPdb
standard
No
A 33-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
GVLATVKNLLNGTGDGAAQSVLKTLSCKLSNDC
Physicochemical Analysis
C138H240N40O48S2
REHIMFPWY
L
3291.78
8.28
3
2
12
+1
3.98
0.212
106.36
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
125
3.80
12
Residue Composition
number
3
A
0
R
3
N
2
D
2
C
0
E
1
Q
4
G
0
H
0
I
6
L
3
K
0
M
0
F
0
P
3
S
3
T
0
W
0
Y
3
V
Amino Acid Distribution
A: 3 R: 0 N: 3 D: 2 C: 2 E: 0 Q: 1 G: 4 H: 0 I: 0 L: 6 K: 3 M: 0 F: 0 P: 0 S: 3 T: 3 W: 0 Y: 0 V: 3
Chemical Descriptors
33
C138H240N40O48S2
3291.78
8.28
+1
3.98
0.212
Evidence Records 12 records
Evidence 1 Activity

Activity

MIC
Antibacterial
7.9 µg/mL

Target

Escherichia coli

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class. DRAMP antibacterial activity supported by MIC records against bacterial target organisms.
Active against Gram- bacteria E. coli (MIC 7.9 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 15.8 ug/ml), Gram+ bacteria S. aureus (MIC
Evidence 2 Activity

Activity

MIC
Antibacterial
4.0 µg/mL

Target

Staphylococcus aureus

Source & Reference

dbAMP DRAMP

Other

MIC 7.9 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 15.8 ug/ml), Gram+ bacteria S. aureus (MIC 4.0 ug/ml), and yeast C. albicans (MIC 4.0 ug/ml). Updated 7/2021
Evidence 3 Activity

Activity

MIC
Antibacterial
4.0 µg/mL

Target

Candida albicans

Source & Reference

dbAMP DRAMP

Other

lled P. aeruginosa) (MIC 15.8 ug/ml), Gram+ bacteria S. aureus (MIC 4.0 ug/ml), and yeast C. albicans (MIC 4.0 ug/ml). Updated 7/2021
Evidence 4 Activity

Activity

MIC
Antifungal
7.9 µg/mL

Target

Escherichia coli

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class. DRAMP antifungal activity supported by activity records against fungal target organisms.
Active against Gram- bacteria E. coli (MIC 7.9 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 15.8 ug/ml), Gram+ bacteria S. aureus (MIC
Evidence 5 Activity

Activity

MIC
Antifungal
4.0 µg/mL

Target

Staphylococcus aureus

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

MIC 7.9 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 15.8 ug/ml), Gram+ bacteria S. aureus (MIC 4.0 ug/ml), and yeast C. albicans (MIC 4.0 ug/ml). Updated 7/2021
Evidence 6 Activity

Activity

MIC
Antifungal
4.0 µg/mL

Target

Candida albicans

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

lled P. aeruginosa) (MIC 15.8 ug/ml), Gram+ bacteria S. aureus (MIC 4.0 ug/ml), and yeast C. albicans (MIC 4.0 ug/ml). Updated 7/2021
Evidence 7 Activity

Activity

MIC
Antiparasitic
7.9 µg/mL

Target

Escherichia coli

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiparasitic
DRAMP antiparasitic activity supported by activity records against parasitic targets.
Active against Gram- bacteria E. coli (MIC 7.9 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 15.8 ug/ml), Gram+ bacteria S. aureus (MIC
Evidence 8 Activity

Activity

MIC
Antiparasitic
4.0 µg/mL

Target

Staphylococcus aureus

Source & Reference

DRAMP

Other

MIC 7.9 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 15.8 ug/ml), Gram+ bacteria S. aureus (MIC 4.0 ug/ml), and yeast C. albicans (MIC 4.0 ug/ml). Updated 7/2021
Evidence 9 Activity

Activity

MIC
Antiparasitic
4.0 µg/mL

Target

Candida albicans

Source & Reference

DRAMP

Other

lled P. aeruginosa) (MIC 15.8 ug/ml), Gram+ bacteria S. aureus (MIC 4.0 ug/ml), and yeast C. albicans (MIC 4.0 ug/ml). Updated 7/2021
Evidence 10 Activity

Activity

MIC
Antiviral
7.9 µg/mL

Target

Escherichia coli

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiviral
DRAMP antiviral activity supported by activity records against viral targets.
Active against Gram- bacteria E. coli (MIC 7.9 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 15.8 ug/ml), Gram+ bacteria S. aureus (MIC
Evidence 11 Activity

Activity

MIC
Antiviral
4.0 µg/mL

Target

Staphylococcus aureus

Source & Reference

DRAMP

Other

MIC 7.9 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 15.8 ug/ml), Gram+ bacteria S. aureus (MIC 4.0 ug/ml), and yeast C. albicans (MIC 4.0 ug/ml). Updated 7/2021
Evidence 12 Activity

Activity

MIC
Antiviral
4.0 µg/mL

Target

Candida albicans

Source & Reference

DRAMP

Other

lled P. aeruginosa) (MIC 15.8 ug/ml), Gram+ bacteria S. aureus (MIC 4.0 ug/ml), and yeast C. albicans (MIC 4.0 ug/ml). Updated 7/2021