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Peptide record

TPDB11464

Antibacterial Anticancer Antifungal Antiparasitic Antiviral standard
33 amino acids
Basic Information
3D PDB MODEL
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TPDB11464
Antibacterial Anticancer Antifungal Antiparasitic Antiviral
Anti-infective peptides Cancer-related peptides
AntiBP3 dbAMP DRAMP Peptipedia AFP-GFuse Antifungipept CAFPdb AVPpred-BWR
standard
No
A 33-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
GVLATVKNLLIGTGDGAAQSVLKTLSCKLSNDC
Physicochemical Analysis
C140H245N39O47S2
REHMFPWY
L
3290.84
8.28
3
2
13
+1
3.25
0.455
118.18
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
125
3.80
11
Residue Composition
number
3
A
0
R
2
N
2
D
2
C
0
E
1
Q
4
G
0
H
1
I
6
L
3
K
0
M
0
F
0
P
3
S
3
T
0
W
0
Y
3
V
Amino Acid Distribution
A: 3 R: 0 N: 2 D: 2 C: 2 E: 0 Q: 1 G: 4 H: 0 I: 1 L: 6 K: 3 M: 0 F: 0 P: 0 S: 3 T: 3 W: 0 Y: 0 V: 3
Chemical Descriptors
33
C140H245N39O47S2
3290.84
8.28
+1
3.25
0.455
Evidence Records 12 records
Evidence 1 Activity

Activity

MIC
Antibacterial
11.2 µg/mL

Target

Escherichia coli

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class. DRAMP antibacterial activity supported by MIC records against bacterial target organisms.
Active against Gram- bacteria E. coli (MIC 11.2 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 44.8 ug/ml), Gram+ bacteria S. aureus (MIC
Evidence 2 Activity

Activity

MIC
Antibacterial
22.4 µg/mL

Target

Staphylococcus aureus

Source & Reference

dbAMP DRAMP

Other

IC 11.2 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 44.8 ug/ml), Gram+ bacteria S. aureus (MIC 22.4 ug/ml), and yeast C. albicans (MIC 11.2 ug/ml). Updated 7/2021
Evidence 3 Activity

Activity

MIC
Antibacterial
11.2 µg/mL

Target

Candida albicans

Source & Reference

dbAMP DRAMP

Other

led P. aeruginosa) (MIC 44.8 ug/ml), Gram+ bacteria S. aureus (MIC 22.4 ug/ml), and yeast C. albicans (MIC 11.2 ug/ml). Updated 7/2021
Evidence 4 Activity

Activity

MIC
Antifungal
11.2 µg/mL

Target

Escherichia coli

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class. DRAMP antifungal activity supported by activity records against fungal target organisms.
Active against Gram- bacteria E. coli (MIC 11.2 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 44.8 ug/ml), Gram+ bacteria S. aureus (MIC
Evidence 5 Activity

Activity

MIC
Antifungal
22.4 µg/mL

Target

Staphylococcus aureus

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

IC 11.2 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 44.8 ug/ml), Gram+ bacteria S. aureus (MIC 22.4 ug/ml), and yeast C. albicans (MIC 11.2 ug/ml). Updated 7/2021
Evidence 6 Activity

Activity

MIC
Antifungal
11.2 µg/mL

Target

Candida albicans

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

led P. aeruginosa) (MIC 44.8 ug/ml), Gram+ bacteria S. aureus (MIC 22.4 ug/ml), and yeast C. albicans (MIC 11.2 ug/ml). Updated 7/2021
Evidence 7 Activity

Activity

MIC
Antiparasitic
11.2 µg/mL

Target

Escherichia coli

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiparasitic
DRAMP antiparasitic activity supported by activity records against parasitic targets.
Active against Gram- bacteria E. coli (MIC 11.2 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 44.8 ug/ml), Gram+ bacteria S. aureus (MIC
Evidence 8 Activity

Activity

MIC
Antiparasitic
22.4 µg/mL

Target

Staphylococcus aureus

Source & Reference

DRAMP

Other

IC 11.2 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 44.8 ug/ml), Gram+ bacteria S. aureus (MIC 22.4 ug/ml), and yeast C. albicans (MIC 11.2 ug/ml). Updated 7/2021
Evidence 9 Activity

Activity

MIC
Antiparasitic
11.2 µg/mL

Target

Candida albicans

Source & Reference

DRAMP

Other

led P. aeruginosa) (MIC 44.8 ug/ml), Gram+ bacteria S. aureus (MIC 22.4 ug/ml), and yeast C. albicans (MIC 11.2 ug/ml). Updated 7/2021
Evidence 10 Activity

Activity

MIC
Antiviral
11.2 µg/mL

Target

Escherichia coli

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiviral
DRAMP antiviral activity supported by activity records against viral targets.
Active against Gram- bacteria E. coli (MIC 11.2 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 44.8 ug/ml), Gram+ bacteria S. aureus (MIC
Evidence 11 Activity

Activity

MIC
Antiviral
22.4 µg/mL

Target

Staphylococcus aureus

Source & Reference

DRAMP

Other

IC 11.2 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 44.8 ug/ml), Gram+ bacteria S. aureus (MIC 22.4 ug/ml), and yeast C. albicans (MIC 11.2 ug/ml). Updated 7/2021
Evidence 12 Activity

Activity

MIC
Antiviral
11.2 µg/mL

Target

Candida albicans

Source & Reference

DRAMP

Other

led P. aeruginosa) (MIC 44.8 ug/ml), Gram+ bacteria S. aureus (MIC 22.4 ug/ml), and yeast C. albicans (MIC 11.2 ug/ml). Updated 7/2021