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Peptide record

TPDB11462

Antibacterial Anticancer Antifungal Antiparasitic Antiviral standard
33 amino acids
Basic Information
3D PDB MODEL
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TPDB11462
Antibacterial Anticancer Antifungal Antiparasitic Antiviral
Anti-infective peptides Cancer-related peptides
AntiBP3 dbAMP DRAMP Peptipedia Antifungipept CAFPdb
standard
No
A 33-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
GLLDTIKNMALNAAKSAGVSVLNSLSCKDSKTC
Physicochemical Analysis
C140H246N40O48S3
REQHFPWY
LS
3353.91
9.05
4
2
13
+2
4.27
0.203
100.61
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
125
3.73
12
Residue Composition
number
4
A
0
R
3
N
2
D
2
C
0
E
0
Q
2
G
0
H
1
I
5
L
4
K
1
M
0
F
0
P
5
S
2
T
0
W
0
Y
2
V
Amino Acid Distribution
A: 4 R: 0 N: 3 D: 2 C: 2 E: 0 Q: 0 G: 2 H: 0 I: 1 L: 5 K: 4 M: 1 F: 0 P: 0 S: 5 T: 2 W: 0 Y: 0 V: 2
Chemical Descriptors
33
C140H246N40O48S3
3353.91
9.05
+2
4.27
0.203
Evidence Records 12 records
Evidence 1 Activity

Activity

MIC
Antibacterial
5.8 µg/mL

Target

Escherichia coli

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class. DRAMP antibacterial activity supported by MIC records against bacterial target organisms.
Active against Gram- bacteria E. coli (MIC 5.8 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 11.6 ug/ml), Gram+ bacteria S. aureus (MIC
Evidence 2 Activity

Activity

MIC
Antibacterial
5.8 µg/mL

Target

Staphylococcus aureus

Source & Reference

dbAMP DRAMP

Other

MIC 5.8 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 11.6 ug/ml), Gram+ bacteria S. aureus (MIC 5.8 ug/ml), and yeast C. albicans (MIC 11.6 ug/ml). Updated 7/2021
Evidence 3 Activity

Activity

MIC
Antibacterial
11.6 µg/mL

Target

Candida albicans

Source & Reference

dbAMP DRAMP

Other

lled P. aeruginosa) (MIC 11.6 ug/ml), Gram+ bacteria S. aureus (MIC 5.8 ug/ml), and yeast C. albicans (MIC 11.6 ug/ml). Updated 7/2021
Evidence 4 Activity

Activity

MIC
Antifungal
5.8 µg/mL

Target

Escherichia coli

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class. DRAMP antifungal activity supported by activity records against fungal target organisms.
Active against Gram- bacteria E. coli (MIC 5.8 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 11.6 ug/ml), Gram+ bacteria S. aureus (MIC
Evidence 5 Activity

Activity

MIC
Antifungal
5.8 µg/mL

Target

Staphylococcus aureus

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

MIC 5.8 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 11.6 ug/ml), Gram+ bacteria S. aureus (MIC 5.8 ug/ml), and yeast C. albicans (MIC 11.6 ug/ml). Updated 7/2021
Evidence 6 Activity

Activity

MIC
Antifungal
11.6 µg/mL

Target

Candida albicans

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

lled P. aeruginosa) (MIC 11.6 ug/ml), Gram+ bacteria S. aureus (MIC 5.8 ug/ml), and yeast C. albicans (MIC 11.6 ug/ml). Updated 7/2021
Evidence 7 Activity

Activity

MIC
Antiparasitic
5.8 µg/mL

Target

Escherichia coli

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiparasitic
DRAMP antiparasitic activity supported by activity records against parasitic targets.
Active against Gram- bacteria E. coli (MIC 5.8 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 11.6 ug/ml), Gram+ bacteria S. aureus (MIC
Evidence 8 Activity

Activity

MIC
Antiparasitic
5.8 µg/mL

Target

Staphylococcus aureus

Source & Reference

DRAMP

Other

MIC 5.8 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 11.6 ug/ml), Gram+ bacteria S. aureus (MIC 5.8 ug/ml), and yeast C. albicans (MIC 11.6 ug/ml). Updated 7/2021
Evidence 9 Activity

Activity

MIC
Antiparasitic
11.6 µg/mL

Target

Candida albicans

Source & Reference

DRAMP

Other

lled P. aeruginosa) (MIC 11.6 ug/ml), Gram+ bacteria S. aureus (MIC 5.8 ug/ml), and yeast C. albicans (MIC 11.6 ug/ml). Updated 7/2021
Evidence 10 Activity

Activity

MIC
Antiviral
5.8 µg/mL

Target

Escherichia coli

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiviral
DRAMP antiviral activity supported by activity records against viral targets.
Active against Gram- bacteria E. coli (MIC 5.8 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 11.6 ug/ml), Gram+ bacteria S. aureus (MIC
Evidence 11 Activity

Activity

MIC
Antiviral
5.8 µg/mL

Target

Staphylococcus aureus

Source & Reference

DRAMP

Other

MIC 5.8 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 11.6 ug/ml), Gram+ bacteria S. aureus (MIC 5.8 ug/ml), and yeast C. albicans (MIC 11.6 ug/ml). Updated 7/2021
Evidence 12 Activity

Activity

MIC
Antiviral
11.6 µg/mL

Target

Candida albicans

Source & Reference

DRAMP

Other

lled P. aeruginosa) (MIC 11.6 ug/ml), Gram+ bacteria S. aureus (MIC 5.8 ug/ml), and yeast C. albicans (MIC 11.6 ug/ml). Updated 7/2021