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Peptide record

TPDB11458

Antibacterial Anticancer Antifungal Antiparasitic Antiviral standard
33 amino acids
Basic Information
3D PDB MODEL
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TPDB11458
Antibacterial Anticancer Antifungal Antiparasitic Antiviral
Anti-infective peptides Cancer-related peptides
AntiBP3 dbAMP DRAMP Peptipedia Antifungipept CAFPdb
standard
No
A 33-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
GLIDTIKNMALNAAKSAGVSVLNTLSCKLSKTC
Physicochemical Analysis
C143H254N40O46S3
REQHFPWY
L
3366.01
9.72
4
1
14
+3
2.74
0.448
112.42
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
125
3.71
12
Residue Composition
number
4
A
0
R
3
N
1
D
2
C
0
E
0
Q
2
G
0
H
2
I
5
L
4
K
1
M
0
F
0
P
4
S
3
T
0
W
0
Y
2
V
Amino Acid Distribution
A: 4 R: 0 N: 3 D: 1 C: 2 E: 0 Q: 0 G: 2 H: 0 I: 2 L: 5 K: 4 M: 1 F: 0 P: 0 S: 4 T: 3 W: 0 Y: 0 V: 2
Chemical Descriptors
33
C143H254N40O46S3
3366.01
9.72
+3
2.74
0.448
Evidence Records 12 records
Evidence 1 Activity

Activity

MIC
Antibacterial
20.6 µg/mL

Target

Escherichia coli

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class. DRAMP antibacterial activity supported by MIC records against bacterial target organisms.
Active against Gram- bacteria E. coli (MIC 20.6 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 41.2 ug/ml), Gram+ bacteria S. aureus (MIC
Evidence 2 Activity

Activity

MIC
Antibacterial
20.6 µg/mL

Target

Staphylococcus aureus

Source & Reference

dbAMP DRAMP

Other

IC 20.6 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 41.2 ug/ml), Gram+ bacteria S. aureus (MIC 20.6 ug/ml), and yeast C. albicans (MIC 10.3 ug/ml). Updated 7/2021
Evidence 3 Activity

Activity

MIC
Antibacterial
10.3 µg/mL

Target

Candida albicans

Source & Reference

dbAMP DRAMP

Other

led P. aeruginosa) (MIC 41.2 ug/ml), Gram+ bacteria S. aureus (MIC 20.6 ug/ml), and yeast C. albicans (MIC 10.3 ug/ml). Updated 7/2021
Evidence 4 Activity

Activity

MIC
Antifungal
20.6 µg/mL

Target

Escherichia coli

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class. DRAMP antifungal activity supported by activity records against fungal target organisms.
Active against Gram- bacteria E. coli (MIC 20.6 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 41.2 ug/ml), Gram+ bacteria S. aureus (MIC
Evidence 5 Activity

Activity

MIC
Antifungal
20.6 µg/mL

Target

Staphylococcus aureus

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

IC 20.6 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 41.2 ug/ml), Gram+ bacteria S. aureus (MIC 20.6 ug/ml), and yeast C. albicans (MIC 10.3 ug/ml). Updated 7/2021
Evidence 6 Activity

Activity

MIC
Antifungal
10.3 µg/mL

Target

Candida albicans

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

led P. aeruginosa) (MIC 41.2 ug/ml), Gram+ bacteria S. aureus (MIC 20.6 ug/ml), and yeast C. albicans (MIC 10.3 ug/ml). Updated 7/2021
Evidence 7 Activity

Activity

MIC
Antiparasitic
20.6 µg/mL

Target

Escherichia coli

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiparasitic
DRAMP antiparasitic activity supported by activity records against parasitic targets.
Active against Gram- bacteria E. coli (MIC 20.6 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 41.2 ug/ml), Gram+ bacteria S. aureus (MIC
Evidence 8 Activity

Activity

MIC
Antiparasitic
20.6 µg/mL

Target

Staphylococcus aureus

Source & Reference

DRAMP

Other

IC 20.6 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 41.2 ug/ml), Gram+ bacteria S. aureus (MIC 20.6 ug/ml), and yeast C. albicans (MIC 10.3 ug/ml). Updated 7/2021
Evidence 9 Activity

Activity

MIC
Antiparasitic
10.3 µg/mL

Target

Candida albicans

Source & Reference

DRAMP

Other

led P. aeruginosa) (MIC 41.2 ug/ml), Gram+ bacteria S. aureus (MIC 20.6 ug/ml), and yeast C. albicans (MIC 10.3 ug/ml). Updated 7/2021
Evidence 10 Activity

Activity

MIC
Antiviral
20.6 µg/mL

Target

Escherichia coli

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiviral
DRAMP antiviral activity supported by activity records against viral targets.
Active against Gram- bacteria E. coli (MIC 20.6 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 41.2 ug/ml), Gram+ bacteria S. aureus (MIC
Evidence 11 Activity

Activity

MIC
Antiviral
20.6 µg/mL

Target

Staphylococcus aureus

Source & Reference

DRAMP

Other

IC 20.6 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 41.2 ug/ml), Gram+ bacteria S. aureus (MIC 20.6 ug/ml), and yeast C. albicans (MIC 10.3 ug/ml). Updated 7/2021
Evidence 12 Activity

Activity

MIC
Antiviral
10.3 µg/mL

Target

Candida albicans

Source & Reference

DRAMP

Other

led P. aeruginosa) (MIC 41.2 ug/ml), Gram+ bacteria S. aureus (MIC 20.6 ug/ml), and yeast C. albicans (MIC 10.3 ug/ml). Updated 7/2021