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Peptide record

TPDB11451

Antibacterial Anticancer Antifungal Antiparasitic Antiviral Toxicity standard
33 amino acids
Basic Information
3D PDB MODEL
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TPDB11451
Antibacterial Anticancer Antifungal Antiparasitic Antiviral Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia ACP740 _ACP240 AntiCP 2.0 iACP-DRLF Antifungipept CAFPdb AI4AVP dbAMP 3.0 DRAVP 2.0 ToxinPred 3.0
standard
No
A 33-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
VCSCRLVFCRRTELRVGNCLIGGVSFTYCCTRV
Physicochemical Analysis
C157H261N49O43S6
ADQHKMPW
C
3715.46
8.60
5
1
12
+4
0.92
0.661
91.21
Mammalian: 100 hour Yeast: >20 hour E.coli: >10 hour
1865
50.20
13
Residue Composition
number
0
A
5
R
1
N
0
D
6
C
1
E
0
Q
3
G
0
H
1
I
3
L
0
K
0
M
2
F
0
P
2
S
3
T
0
W
1
Y
5
V
Amino Acid Distribution
A: 0 R: 5 N: 1 D: 0 C: 6 E: 1 Q: 0 G: 3 H: 0 I: 1 L: 3 K: 0 M: 0 F: 2 P: 0 S: 2 T: 3 W: 0 Y: 1 V: 5
Chemical Descriptors
33
C157H261N49O43S6
3715.46
8.60
+4
0.92
0.661
Evidence Records 5 records
Evidence 1 Activity

Activity

Antibacterial

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
Active against E. coli, S. faecalis, and C. albicans.
Evidence 2 Activity

Activity

Antifungal

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
Active against E. coli, S. faecalis, and C. albicans.
Evidence 3 Activity

Activity

Antiparasitic

Source & Reference

dbAMP 3.0 DRAMP

Other

Source Activity Label Source Definition
Antiparasitic
dbAMP 3.0 classified under the Anti-parasitic function class.
Active against E. coli, S. faecalis, and C. albicans.
Evidence 4 Activity

Activity

Antiviral

Source & Reference

dbAMP 3.0 DRAMP DRAVP 2.0

Other

Source Activity Label Source Definition
Antiviral
dbAMP 3.0 classified under the Anti-viral function class.
Active against E. coli, S. faecalis, and C. albicans.
Evidence 5 Activity

Activity

50% Cytotoxicity
Toxicity
19 µM
Cytotoxic
50% Cytotoxicity | 19 | µM | target cell: Human retinal epithelial cells ARPE-19

Target

Human retinal epithelial cells ARPE-19

Source & Reference

NA
DBAASP
The Human ?-Defensin-Derived Peptide HD5(1-9) Inhibits Cellular Attachment and Entry of Human Cytomegalovirus | Antiviral Res | 2020