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Peptide record

TPDB11448

Antibacterial Antifungal Hemolysis Toxicity standard
33 amino acids
Basic Information
3D PDB MODEL
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TPDB11448
Antibacterial Antifungal Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia Antifungipept CAFPdb HemoPI Hemolytic2 PD_Hemolysis ToxinPred 3.0
standard
No
A 33-aa standard natural multi-activity (Antibacterial, Antifungal, Hemolysis, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
GILDKLKEFGISAARGVAQSLLNTASCKLAKTC
Physicochemical Analysis
C148H256N42O45S2
HMPWY
AL
3408.03
9.71
5
2
14
+3
3.91
0.300
106.67
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
125
3.67
9
Residue Composition
number
5
A
1
R
1
N
1
D
2
C
1
E
1
Q
3
G
0
H
2
I
5
L
4
K
0
M
1
F
0
P
3
S
2
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 5 R: 1 N: 1 D: 1 C: 2 E: 1 Q: 1 G: 3 H: 0 I: 2 L: 5 K: 4 M: 0 F: 1 P: 0 S: 3 T: 2 W: 0 Y: 0 V: 1
Chemical Descriptors
33
C148H256N42O45S2
3408.03
9.71
+3
3.91
0.300
Evidence Records 2 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
75 µM
Hemolytic Cytotoxic
50% Hemolysis | 75 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Characterization of diverse antimicrobial peptides in skin secretions of Chungan torrent frog Amolops chunganensis | Peptides | 2012
Evidence 2 Hemolysis

Source & Reference

HemoPI PD_Hemolysis
PD_Hemolysis