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Peptide record

TPDB11447

Antibacterial Antifungal Hemolysis Toxicity standard
33 amino acids
Basic Information
3D PDB MODEL
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TPDB11447
Antibacterial Antifungal Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia Antifungipept CAFPdb HemoPI Hemolytic2 PD_Hemolysis ToxinPred 3.0
standard
No
A 33-aa standard natural multi-activity (Antibacterial, Antifungal, Hemolysis, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
SLLGTVKDLLIGAGKSAAQSVLKGLSCKLSKDC
Physicochemical Analysis
C143H255N39O45S2
RNEHMFPWY
L
3304.95
9.65
5
2
13
+3
3.74
0.412
121.21
Mammalian: 1.9 hour Yeast: >20 hour E.coli: >10 hour
125
3.78
9
Residue Composition
number
3
A
0
R
0
N
2
D
2
C
0
E
1
Q
4
G
0
H
1
I
7
L
5
K
0
M
0
F
0
P
5
S
1
T
0
W
0
Y
2
V
Amino Acid Distribution
A: 3 R: 0 N: 0 D: 2 C: 2 E: 0 Q: 1 G: 4 H: 0 I: 1 L: 7 K: 5 M: 0 F: 0 P: 0 S: 5 T: 1 W: 0 Y: 0 V: 2
Chemical Descriptors
33
C143H255N39O45S2
3304.95
9.65
+3
3.74
0.412
Evidence Records 4 records
Evidence 1 Activity

Activity

LC50
Hemolysis
300 µM
LC50=300µM against human erythrocytes

Target

human erythrocytes

Source & Reference

Hemolytik PD_Hemolysis
DRAMP4
Peptides. 2008 Aug 29(8):1456-1460.

Other

Source Activity Label Source Definition
Hemolysis
Hemolytik experimentally validated hemolytic peptide annotation.
Evidence 2 Activity

Activity

50% Hemolysis
Toxicity
300 µM
Hemolytic Cytotoxic
50% Hemolysis | 300 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Novel antimicrobial peptides isolated from the skin secretions of Hainan odorous frog, Odorrana hainanensis. | Peptides | 2012
Evidence 3 Activity

Activity

LC50
Toxicity
300 µM
Hemolytic
Hemolytic_activity: LC50=300µM against human erythrocytes

Target

erythrocytes

Source & Reference

NA
DRAMP
Peptides. 2008 Aug 29(8):1456-1460.
Evidence 4 Hemolysis

Activity

300 µM
LC50
LC50=300µM against human erythrocytes
Hemolysis

Target

human erythrocytes

Source & Reference

HemoPI PD_Hemolysis
Peptides. 2008 Aug 29(8):1456-1460.
DRAMP4
PD_Hemolysis