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Peptide record

TPDB11445

Antibacterial Antifungal standard
33 amino acids
Basic Information
3D PDB MODEL
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TPDB11445
Antibacterial Antifungal
Anti-infective peptides
AntiBP3 Peptipedia Antifungipept CAFPdb dbAMP
standard
No
A 33-aa standard-residue multi-activity (Antibacterial and Antifungal) peptide sequence curated from AntiBP3, Peptipedia, Antifungipept, and other sources, with an available 3D structural model.
Sequence
KKCGFFCKLKNKLKSTGSRSNIAAGTHGGTFRV
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C155H257N49O42S2
DEQMPWY
K
3543.17
11.16
9
0
9
+8
1.83
-0.479
50.30
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
125
0.04
10
Residue Composition
number
2
A
2
R
2
N
0
D
2
C
0
E
0
Q
5
G
1
H
1
I
2
L
6
K
0
M
3
F
0
P
3
S
3
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 2 R: 2 N: 2 D: 0 C: 2 E: 0 Q: 0 G: 5 H: 1 I: 1 L: 2 K: 6 M: 0 F: 3 P: 0 S: 3 T: 3 W: 0 Y: 0 V: 1
Chemical Descriptors
33 reviewed residue count
C155H257N49O42S2 sequence-only estimate (linear, free termini)
3543.17 sequence-only estimate (linear, free termini)
11.16 sequence-only estimate (linear, free termini)
+8 sequence-only estimate (linear, free termini)
1.83 sequence-only estimate (linear, free termini)
-0.479 sequence-only estimate (linear, free termini)
Evidence Records 4 records
Evidence 1 Activity

Activity

MIC
Antibacterial
42.36 µM

Target

P. mirabilis

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
Active against P. mirabilis (MIC 42.36 uM) and S. maltophilia clinial strains (MIC 42.36 uM). Updated 7/2021 11/2023
Evidence 2 Activity

Activity

MIC
Antibacterial
42.36 µM

Target

Stenotrophomonas maltophilia clinial strains

Source & Reference

dbAMP

Other

Active against P. mirabilis (MIC 42.36 uM) and S. maltophilia clinial strains (MIC 42.36 uM). Updated 7/2021 11/2023
Evidence 3 Activity

Activity

MIC
Antifungal
42.36 µM

Target

P. mirabilis

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
Active against P. mirabilis (MIC 42.36 uM) and S. maltophilia clinial strains (MIC 42.36 uM). Updated 7/2021 11/2023
Evidence 4 Activity

Activity

MIC
Antifungal
42.36 µM

Target

Stenotrophomonas maltophilia clinial strains

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Active against P. mirabilis (MIC 42.36 uM) and S. maltophilia clinial strains (MIC 42.36 uM). Updated 7/2021 11/2023