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Peptide record

TPDB11441

Anti-inflammatory Antibacterial Anticancer Antifungal Antiparasitic Antiviral Hemolysis Toxicity standard
33 amino acids
Basic Information
3D PDB MODEL
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TPDB11441
Anti-inflammatory Antibacterial Anticancer Antifungal Antiparasitic Antiviral Hemolysis Toxicity
Anti-infective peptides Cancer-related peptides Immunity and inflammation peptides Toxicity and safety peptides
Peptipedia AntiBP3 dbAMP Antifungipept CAFPdb APD_complete PD_Hemolysis ToxinPred 3.0
standard
No
A 33-aa standard natural multi-activity (Anti-inflammatory, Antibacterial, Anticancer, and other sources) peptide sequence curated from Peptipedia, AntiBP3, dbAMP, and other sources, with an available 3D structural model.
Sequence
GILDTLKNLAKTAGKGILKSLVNTASCKLSGQC
Physicochemical Analysis
C144H257N41O45S2
REHMFPWY
L
3346.99
10.06
5
1
12
+4
3.55
0.206
112.42
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
125
3.73
11
Residue Composition
number
3
A
0
R
2
N
1
D
2
C
0
E
1
Q
4
G
0
H
2
I
6
L
5
K
0
M
0
F
0
P
3
S
3
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 3 R: 0 N: 2 D: 1 C: 2 E: 0 Q: 1 G: 4 H: 0 I: 2 L: 6 K: 5 M: 0 F: 0 P: 0 S: 3 T: 3 W: 0 Y: 0 V: 1
Chemical Descriptors
33
C144H257N41O45S2
3346.99
10.06
+4
3.55
0.206
Evidence Records 17 records
Evidence 1 Activity

Activity

MIC
Antibacterial
20 µM

Target

Staphylococcus aureus

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
Broadly active against S. aureus (MIC 20 uM), E. coli (MIC 10 uM) and C. albicans (MIC 20 uM).
Evidence 2 Activity

Activity

MIC
Antibacterial
10 µM

Target

Escherichia coli

Source & Reference

dbAMP

Other

Broadly active against S. aureus (MIC 20 uM), E. coli (MIC 10 uM) and C. albicans (MIC 20 uM).
Evidence 3 Activity

Activity

MIC
Antibacterial
20 µM

Target

Candida albicans

Source & Reference

dbAMP

Other

Broadly active against S. aureus (MIC 20 uM), E. coli (MIC 10 uM) and C. albicans (MIC 20 uM).
Evidence 4 Activity

Activity

MIC
Antifungal
20 µM

Target

Staphylococcus aureus

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
Broadly active against S. aureus (MIC 20 uM), E. coli (MIC 10 uM) and C. albicans (MIC 20 uM).
Evidence 5 Activity

Activity

MIC
Antifungal
10 µM

Target

Escherichia coli

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Broadly active against S. aureus (MIC 20 uM), E. coli (MIC 10 uM) and C. albicans (MIC 20 uM).
Evidence 6 Activity

Activity

MIC
Antifungal
20 µM

Target

Candida albicans

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Broadly active against S. aureus (MIC 20 uM), E. coli (MIC 10 uM) and C. albicans (MIC 20 uM).
Evidence 7 Activity

Activity

MIC
Antiparasitic
20 µM

Target

Staphylococcus aureus

Source & Reference

NA

Other

Broadly active against S. aureus (MIC 20 uM), E. coli (MIC 10 uM) and C. albicans (MIC 20 uM).
Evidence 8 Activity

Activity

MIC
Antiparasitic
10 µM

Target

Escherichia coli

Source & Reference

NA

Other

Broadly active against S. aureus (MIC 20 uM), E. coli (MIC 10 uM) and C. albicans (MIC 20 uM).
Evidence 9 Activity

Activity

MIC
Antiparasitic
20 µM

Target

Candida albicans

Source & Reference

NA

Other

Broadly active against S. aureus (MIC 20 uM), E. coli (MIC 10 uM) and C. albicans (MIC 20 uM).
Evidence 10 Activity

Activity

MIC
Antiviral
20 µM

Target

Staphylococcus aureus

Source & Reference

NA

Other

Broadly active against S. aureus (MIC 20 uM), E. coli (MIC 10 uM) and C. albicans (MIC 20 uM).
Evidence 11 Activity

Activity

MIC
Antiviral
10 µM

Target

Escherichia coli

Source & Reference

NA

Other

Broadly active against S. aureus (MIC 20 uM), E. coli (MIC 10 uM) and C. albicans (MIC 20 uM).
Evidence 12 Activity

Activity

MIC
Antiviral
20 µM

Target

Candida albicans

Source & Reference

NA

Other

Broadly active against S. aureus (MIC 20 uM), E. coli (MIC 10 uM) and C. albicans (MIC 20 uM).
Evidence 13 Activity

Activity

0% Hemolysis
Toxicity
32 µg/mL
Hemolytic Cytotoxic
0% Hemolysis | 32 | µg/mL | target cell: Horse erythrocytes

Target

Horse erythrocytes

Source & Reference

NA
DBAASP
Assessment of antimicrobial and wound healing effects of Brevinin-2Ta against the bacterium Klebsiella pneumoniae in dermally-wounded rats. | Oncotarget | 2017
Evidence 14 Activity

Activity

10% Hemolysis
Toxicity
64 µg/mL
Hemolytic Cytotoxic
10% Hemolysis | 64 | µg/mL | target cell: Horse erythrocytes

Target

Horse erythrocytes

Source & Reference

NA
DBAASP
Assessment of antimicrobial and wound healing effects of Brevinin-2Ta against the bacterium Klebsiella pneumoniae in dermally-wounded rats. | Oncotarget | 2017
Evidence 15 Activity

Activity

18% Hemolysis
Toxicity
128 µg/mL
Hemolytic Cytotoxic
18% Hemolysis | 128 | µg/mL | target cell: Horse erythrocytes

Target

Horse erythrocytes

Source & Reference

NA
DBAASP
Assessment of antimicrobial and wound healing effects of Brevinin-2Ta against the bacterium Klebsiella pneumoniae in dermally-wounded rats. | Oncotarget | 2017
Evidence 16 Activity

Activity

30% Hemolysis
Toxicity
256 µg/mL
Hemolytic Cytotoxic
30% Hemolysis | 256 | µg/mL | target cell: Horse erythrocytes

Target

Horse erythrocytes

Source & Reference

NA
DBAASP
Assessment of antimicrobial and wound healing effects of Brevinin-2Ta against the bacterium Klebsiella pneumoniae in dermally-wounded rats. | Oncotarget | 2017
Evidence 17 Hemolysis

Source & Reference

APD_complete PD_Hemolysis
APD_complete PD_Hemolysis

Other

Source Activity Label Source Definition
Hemolysis
APD_complete APD-derived hemolytic peptide annotation.