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Peptide record

TPDB11435

Antibacterial Anticancer Antifungal Antiparasitic Antiviral standard
33 amino acids
Basic Information
3D PDB MODEL
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TPDB11435
Antibacterial Anticancer Antifungal Antiparasitic Antiviral
Anti-infective peptides Cancer-related peptides
AntiBP3 dbAMP DRAMP Peptipedia AntiCP 2.0 iACP-DRLF Antifungipept CAFPdb
standard
No
A 33-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
GLLDTFKNLAINAAESAGVSVLNSLSCKLSKTC
Physicochemical Analysis
C145H247N39O48S2
RQHMPWY
L
3368.91
8.28
3
2
14
+1
2.61
0.464
112.42
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
125
3.71
12
Residue Composition
number
4
A
0
R
3
N
1
D
2
C
1
E
0
Q
2
G
0
H
1
I
6
L
3
K
0
M
1
F
0
P
5
S
2
T
0
W
0
Y
2
V
Amino Acid Distribution
A: 4 R: 0 N: 3 D: 1 C: 2 E: 1 Q: 0 G: 2 H: 0 I: 1 L: 6 K: 3 M: 0 F: 1 P: 0 S: 5 T: 2 W: 0 Y: 0 V: 2
Chemical Descriptors
33
C145H247N39O48S2
3368.91
8.28
+1
2.61
0.464
Evidence Records 12 records
Evidence 1 Activity

Activity

MIC
Antibacterial
20.0 µg/mL

Target

Escherichia coli

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class. DRAMP antibacterial activity supported by MIC records against bacterial target organisms.
Active against Gram- bacteria E. coli (MIC 20.0 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 20.0 ug/ml), Gram+ bacteria S. aureus (MIC
Evidence 2 Activity

Activity

MIC
Antibacterial
10.0 µg/mL

Target

Staphylococcus aureus

Source & Reference

dbAMP DRAMP

Other

IC 20.0 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 20.0 ug/ml), Gram+ bacteria S. aureus (MIC 10.0 ug/ml), and yeast C. albicans (MIC 10.0 ug/ml). Updated 7/2021
Evidence 3 Activity

Activity

MIC
Antibacterial
10.0 µg/mL

Target

Candida albicans

Source & Reference

dbAMP DRAMP

Other

led P. aeruginosa) (MIC 20.0 ug/ml), Gram+ bacteria S. aureus (MIC 10.0 ug/ml), and yeast C. albicans (MIC 10.0 ug/ml). Updated 7/2021
Evidence 4 Activity

Activity

MIC
Antifungal
20.0 µg/mL

Target

Escherichia coli

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class. DRAMP antifungal activity supported by activity records against fungal target organisms.
Active against Gram- bacteria E. coli (MIC 20.0 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 20.0 ug/ml), Gram+ bacteria S. aureus (MIC
Evidence 5 Activity

Activity

MIC
Antifungal
10.0 µg/mL

Target

Staphylococcus aureus

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

IC 20.0 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 20.0 ug/ml), Gram+ bacteria S. aureus (MIC 10.0 ug/ml), and yeast C. albicans (MIC 10.0 ug/ml). Updated 7/2021
Evidence 6 Activity

Activity

MIC
Antifungal
10.0 µg/mL

Target

Candida albicans

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

led P. aeruginosa) (MIC 20.0 ug/ml), Gram+ bacteria S. aureus (MIC 10.0 ug/ml), and yeast C. albicans (MIC 10.0 ug/ml). Updated 7/2021
Evidence 7 Activity

Activity

MIC
Antiparasitic
20.0 µg/mL

Target

Escherichia coli

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiparasitic
DRAMP antiparasitic activity supported by activity records against parasitic targets.
Active against Gram- bacteria E. coli (MIC 20.0 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 20.0 ug/ml), Gram+ bacteria S. aureus (MIC
Evidence 8 Activity

Activity

MIC
Antiparasitic
10.0 µg/mL

Target

Staphylococcus aureus

Source & Reference

DRAMP

Other

IC 20.0 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 20.0 ug/ml), Gram+ bacteria S. aureus (MIC 10.0 ug/ml), and yeast C. albicans (MIC 10.0 ug/ml). Updated 7/2021
Evidence 9 Activity

Activity

MIC
Antiparasitic
10.0 µg/mL

Target

Candida albicans

Source & Reference

DRAMP

Other

led P. aeruginosa) (MIC 20.0 ug/ml), Gram+ bacteria S. aureus (MIC 10.0 ug/ml), and yeast C. albicans (MIC 10.0 ug/ml). Updated 7/2021
Evidence 10 Activity

Activity

MIC
Antiviral
20.0 µg/mL

Target

Escherichia coli

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiviral
DRAMP antiviral activity supported by activity records against viral targets.
Active against Gram- bacteria E. coli (MIC 20.0 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 20.0 ug/ml), Gram+ bacteria S. aureus (MIC
Evidence 11 Activity

Activity

MIC
Antiviral
10.0 µg/mL

Target

Staphylococcus aureus

Source & Reference

DRAMP

Other

IC 20.0 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 20.0 ug/ml), Gram+ bacteria S. aureus (MIC 10.0 ug/ml), and yeast C. albicans (MIC 10.0 ug/ml). Updated 7/2021
Evidence 12 Activity

Activity

MIC
Antiviral
10.0 µg/mL

Target

Candida albicans

Source & Reference

DRAMP

Other

led P. aeruginosa) (MIC 20.0 ug/ml), Gram+ bacteria S. aureus (MIC 10.0 ug/ml), and yeast C. albicans (MIC 10.0 ug/ml). Updated 7/2021