Back to search

Peptide record

TPDB11429

Antibacterial Anticancer Antifungal Antiparasitic Antiviral standard
33 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB11429
Antibacterial Anticancer Antifungal Antiparasitic Antiviral
Anti-infective peptides Cancer-related peptides
AntiBP3 dbAMP DRAMP Peptipedia dbACP Antifungipept CAFPdb DRAVP 2.0
standard
No
A 33-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
GLLRKGGEKIGEKLKKIGQKIKNFFQKLVPQPE
Physicochemical Analysis
C173H294N48O44
ADCHMSTWY
K
3750.53
10.74
9
3
10
+6
12.54
-0.815
91.52
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
4
Residue Composition
number
0
A
1
R
1
N
0
D
0
C
3
E
3
Q
5
G
0
H
3
I
4
L
8
K
0
M
2
F
2
P
0
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 0 R: 1 N: 1 D: 0 C: 0 E: 3 Q: 3 G: 5 H: 0 I: 3 L: 4 K: 8 M: 0 F: 2 P: 2 S: 0 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
33
C173H294N48O44
3750.53
10.74
+6
12.54
-0.815
Evidence Records 40 records
Evidence 1 Activity

Activity

MIC
Antibacterial
0.5-2 µM

Target

Escherichia coli ATCC 25922 or ML35 or D21

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class. DRAMP antibacterial activity supported by MIC records against bacterial target organisms.
Active against E. coli ATCC 25922 or ML35 or D21 (MIC 0.5-2 uM), S. typhimurium ATCC 14028 (MIC 8 uM), P. aeruginosa ATCC 27853 (MIC 4 uM), S. marcescens
Evidence 2 Activity

Activity

MIC
Antibacterial
8 µM

Target

S. typhimurium ATCC 14028

Source & Reference

dbAMP DRAMP

Other

Active against E. coli ATCC 25922 or ML35 or D21 (MIC 0.5-2 uM), S. typhimurium ATCC 14028 (MIC 8 uM), P. aeruginosa ATCC 27853 (MIC 4 uM), S. marcescens ATCC 8100 (MIC 4 uM), P-vulgaris ATCC
Evidence 3 Activity

Activity

MIC
Antibacterial
4 µM

Target

Pseudomonas aeruginosa ATCC 27853

Source & Reference

dbAMP DRAMP

Other

t E. coli ATCC 25922 or ML35 or D21 (MIC 0.5-2 uM), S. typhimurium ATCC 14028 (MIC 8 uM), P. aeruginosa ATCC 27853 (MIC 4 uM), S. marcescens ATCC 8100 (MIC 4 uM), P-vulgaris ATCC 13315 (MIC>64 uM), S. aureus ATCC 25
Evidence 4 Activity

Activity

MIC
Antibacterial
4 µM

Target

S. marcescens ATCC 8100

Source & Reference

dbAMP DRAMP

Other

MIC 0.5-2 uM), S. typhimurium ATCC 14028 (MIC 8 uM), P. aeruginosa ATCC 27853 (MIC 4 uM), S. marcescens ATCC 8100 (MIC 4 uM), P-vulgaris ATCC 13315 (MIC>64 uM), S. aureus ATCC 25923 or Cowan I MRSA (MIC 32-64 uM),
Evidence 5 Activity

Activity

MIC
Antibacterial
32-64 µM

Target

Staphylococcus aureus ATCC 25923 or Cowan I MRSA

Source & Reference

dbAMP DRAMP

Other

27853 (MIC 4 uM), S. marcescens ATCC 8100 (MIC 4 uM), P-vulgaris ATCC 13315 (MIC>64 uM), S. aureus ATCC 25923 or Cowan I MRSA (MIC 32-64 uM), S. epidermidis ATCC 12228 (MIC 16 uM), S. faecalis ATCC 29212 (MIC 32 uM), B. megaterium
Evidence 6 Activity

Activity

MIC
Antibacterial
16 µM

Target

Staphylococcus epidermidis ATCC 12228

Source & Reference

dbAMP DRAMP

Other

, P-vulgaris ATCC 13315 (MIC>64 uM), S. aureus ATCC 25923 or Cowan I MRSA (MIC 32-64 uM), S. epidermidis ATCC 12228 (MIC 16 uM), S. faecalis ATCC 29212 (MIC 32 uM), B. megaterium Bm11 (MIC 4 uM), fumgi C-albicans (MIC
Evidence 7 Activity

Activity

MIC
Antibacterial
32 µM

Target

S. faecalis ATCC 29212

Source & Reference

dbAMP DRAMP

Other

aureus ATCC 25923 or Cowan I MRSA (MIC 32-64 uM), S. epidermidis ATCC 12228 (MIC 16 uM), S. faecalis ATCC 29212 (MIC 32 uM), B. megaterium Bm11 (MIC 4 uM), fumgi C-albicans (MIC > 64 uM), C. neoformans (MIC 16 uM)
Evidence 8 Activity

Activity

MIC
Antibacterial
4 µM

Target

B. megaterium Bm11

Source & Reference

dbAMP DRAMP

Other

MIC 32-64 uM), S. epidermidis ATCC 12228 (MIC 16 uM), S. faecalis ATCC 29212 (MIC 32 uM), B. megaterium Bm11 (MIC 4 uM), fumgi C-albicans (MIC > 64 uM), C. neoformans (MIC 16 uM), and the single-stranded RNA v
Evidence 9 Activity

Activity

MIC
Antibacterial
16 µM

Target

C. neoformans

Source & Reference

dbAMP DRAMP

Other

is ATCC 29212 (MIC 32 uM), B. megaterium Bm11 (MIC 4 uM), fumgi C-albicans (MIC > 64 uM), C. neoformans (MIC 16 uM), and the single-stranded RNA virus respiratory syncytial virus (RSV). It also inhibit B.
Evidence 10 Activity

Activity

MIC
Antibacterial
8 µg/mL

Target

B. anthracis

Source & Reference

dbAMP DRAMP

Other

uM), and the single-stranded RNA virus respiratory syncytial virus (RSV). It also inhibit B. anthracis (MIC 8 ug/ml) ( Blower et al., 2018 ). IL-17A and IL-17F are essential for the production of CRAMP to c
Evidence 11 Activity

Activity

MIC
Antifungal
0.5-2 µM

Target

Escherichia coli ATCC 25922 or ML35 or D21

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class. DRAMP antifungal activity supported by activity records against fungal target organisms.
Active against E. coli ATCC 25922 or ML35 or D21 (MIC 0.5-2 uM), S. typhimurium ATCC 14028 (MIC 8 uM), P. aeruginosa ATCC 27853 (MIC 4 uM), S. marcescens
Evidence 12 Activity

Activity

MIC
Antifungal
8 µM

Target

S. typhimurium ATCC 14028

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Active against E. coli ATCC 25922 or ML35 or D21 (MIC 0.5-2 uM), S. typhimurium ATCC 14028 (MIC 8 uM), P. aeruginosa ATCC 27853 (MIC 4 uM), S. marcescens ATCC 8100 (MIC 4 uM), P-vulgaris ATCC
Evidence 13 Activity

Activity

MIC
Antifungal
4 µM

Target

Pseudomonas aeruginosa ATCC 27853

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

t E. coli ATCC 25922 or ML35 or D21 (MIC 0.5-2 uM), S. typhimurium ATCC 14028 (MIC 8 uM), P. aeruginosa ATCC 27853 (MIC 4 uM), S. marcescens ATCC 8100 (MIC 4 uM), P-vulgaris ATCC 13315 (MIC>64 uM), S. aureus ATCC 25
Evidence 14 Activity

Activity

MIC
Antifungal
4 µM

Target

S. marcescens ATCC 8100

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

MIC 0.5-2 uM), S. typhimurium ATCC 14028 (MIC 8 uM), P. aeruginosa ATCC 27853 (MIC 4 uM), S. marcescens ATCC 8100 (MIC 4 uM), P-vulgaris ATCC 13315 (MIC>64 uM), S. aureus ATCC 25923 or Cowan I MRSA (MIC 32-64 uM),
Evidence 15 Activity

Activity

MIC
Antifungal
32-64 µM

Target

Staphylococcus aureus ATCC 25923 or Cowan I MRSA

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

27853 (MIC 4 uM), S. marcescens ATCC 8100 (MIC 4 uM), P-vulgaris ATCC 13315 (MIC>64 uM), S. aureus ATCC 25923 or Cowan I MRSA (MIC 32-64 uM), S. epidermidis ATCC 12228 (MIC 16 uM), S. faecalis ATCC 29212 (MIC 32 uM), B. megaterium
Evidence 16 Activity

Activity

MIC
Antifungal
16 µM

Target

Staphylococcus epidermidis ATCC 12228

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

, P-vulgaris ATCC 13315 (MIC>64 uM), S. aureus ATCC 25923 or Cowan I MRSA (MIC 32-64 uM), S. epidermidis ATCC 12228 (MIC 16 uM), S. faecalis ATCC 29212 (MIC 32 uM), B. megaterium Bm11 (MIC 4 uM), fumgi C-albicans (MIC
Evidence 17 Activity

Activity

MIC
Antifungal
32 µM

Target

S. faecalis ATCC 29212

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

aureus ATCC 25923 or Cowan I MRSA (MIC 32-64 uM), S. epidermidis ATCC 12228 (MIC 16 uM), S. faecalis ATCC 29212 (MIC 32 uM), B. megaterium Bm11 (MIC 4 uM), fumgi C-albicans (MIC > 64 uM), C. neoformans (MIC 16 uM)
Evidence 18 Activity

Activity

MIC
Antifungal
4 µM

Target

B. megaterium Bm11

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

MIC 32-64 uM), S. epidermidis ATCC 12228 (MIC 16 uM), S. faecalis ATCC 29212 (MIC 32 uM), B. megaterium Bm11 (MIC 4 uM), fumgi C-albicans (MIC > 64 uM), C. neoformans (MIC 16 uM), and the single-stranded RNA v
Evidence 19 Activity

Activity

MIC
Antifungal
16 µM

Target

C. neoformans

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

is ATCC 29212 (MIC 32 uM), B. megaterium Bm11 (MIC 4 uM), fumgi C-albicans (MIC > 64 uM), C. neoformans (MIC 16 uM), and the single-stranded RNA virus respiratory syncytial virus (RSV). It also inhibit B.
Evidence 20 Activity

Activity

MIC
Antifungal
8 µg/mL

Target

B. anthracis

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

uM), and the single-stranded RNA virus respiratory syncytial virus (RSV). It also inhibit B. anthracis (MIC 8 ug/ml) ( Blower et al., 2018 ). IL-17A and IL-17F are essential for the production of CRAMP to c
Evidence 21 Activity

Activity

MIC
Antiparasitic
0.5-2 µM

Target

Escherichia coli ATCC 25922 or ML35 or D21

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiparasitic
DRAMP antiparasitic activity supported by activity records against parasitic targets.
Active against E. coli ATCC 25922 or ML35 or D21 (MIC 0.5-2 uM), S. typhimurium ATCC 14028 (MIC 8 uM), P. aeruginosa ATCC 27853 (MIC 4 uM), S. marcescens
Evidence 22 Activity

Activity

MIC
Antiparasitic
8 µM

Target

S. typhimurium ATCC 14028

Source & Reference

DRAMP

Other

Active against E. coli ATCC 25922 or ML35 or D21 (MIC 0.5-2 uM), S. typhimurium ATCC 14028 (MIC 8 uM), P. aeruginosa ATCC 27853 (MIC 4 uM), S. marcescens ATCC 8100 (MIC 4 uM), P-vulgaris ATCC
Evidence 23 Activity

Activity

MIC
Antiparasitic
4 µM

Target

Pseudomonas aeruginosa ATCC 27853

Source & Reference

DRAMP

Other

t E. coli ATCC 25922 or ML35 or D21 (MIC 0.5-2 uM), S. typhimurium ATCC 14028 (MIC 8 uM), P. aeruginosa ATCC 27853 (MIC 4 uM), S. marcescens ATCC 8100 (MIC 4 uM), P-vulgaris ATCC 13315 (MIC>64 uM), S. aureus ATCC 25
Evidence 24 Activity

Activity

MIC
Antiparasitic
4 µM

Target

S. marcescens ATCC 8100

Source & Reference

DRAMP

Other

MIC 0.5-2 uM), S. typhimurium ATCC 14028 (MIC 8 uM), P. aeruginosa ATCC 27853 (MIC 4 uM), S. marcescens ATCC 8100 (MIC 4 uM), P-vulgaris ATCC 13315 (MIC>64 uM), S. aureus ATCC 25923 or Cowan I MRSA (MIC 32-64 uM),
Evidence 25 Activity

Activity

MIC
Antiparasitic
32-64 µM

Target

Staphylococcus aureus ATCC 25923 or Cowan I MRSA

Source & Reference

DRAMP

Other

27853 (MIC 4 uM), S. marcescens ATCC 8100 (MIC 4 uM), P-vulgaris ATCC 13315 (MIC>64 uM), S. aureus ATCC 25923 or Cowan I MRSA (MIC 32-64 uM), S. epidermidis ATCC 12228 (MIC 16 uM), S. faecalis ATCC 29212 (MIC 32 uM), B. megaterium
Evidence 26 Activity

Activity

MIC
Antiparasitic
16 µM

Target

Staphylococcus epidermidis ATCC 12228

Source & Reference

DRAMP

Other

, P-vulgaris ATCC 13315 (MIC>64 uM), S. aureus ATCC 25923 or Cowan I MRSA (MIC 32-64 uM), S. epidermidis ATCC 12228 (MIC 16 uM), S. faecalis ATCC 29212 (MIC 32 uM), B. megaterium Bm11 (MIC 4 uM), fumgi C-albicans (MIC
Evidence 27 Activity

Activity

MIC
Antiparasitic
32 µM

Target

S. faecalis ATCC 29212

Source & Reference

DRAMP

Other

aureus ATCC 25923 or Cowan I MRSA (MIC 32-64 uM), S. epidermidis ATCC 12228 (MIC 16 uM), S. faecalis ATCC 29212 (MIC 32 uM), B. megaterium Bm11 (MIC 4 uM), fumgi C-albicans (MIC > 64 uM), C. neoformans (MIC 16 uM)
Evidence 28 Activity

Activity

MIC
Antiparasitic
4 µM

Target

B. megaterium Bm11

Source & Reference

DRAMP

Other

MIC 32-64 uM), S. epidermidis ATCC 12228 (MIC 16 uM), S. faecalis ATCC 29212 (MIC 32 uM), B. megaterium Bm11 (MIC 4 uM), fumgi C-albicans (MIC > 64 uM), C. neoformans (MIC 16 uM), and the single-stranded RNA v
Evidence 29 Activity

Activity

MIC
Antiparasitic
16 µM

Target

C. neoformans

Source & Reference

DRAMP

Other

is ATCC 29212 (MIC 32 uM), B. megaterium Bm11 (MIC 4 uM), fumgi C-albicans (MIC > 64 uM), C. neoformans (MIC 16 uM), and the single-stranded RNA virus respiratory syncytial virus (RSV). It also inhibit B.
Evidence 30 Activity

Activity

MIC
Antiparasitic
8 µg/mL

Target

B. anthracis

Source & Reference

DRAMP

Other

uM), and the single-stranded RNA virus respiratory syncytial virus (RSV). It also inhibit B. anthracis (MIC 8 ug/ml) ( Blower et al., 2018 ). IL-17A and IL-17F are essential for the production of CRAMP to c
Evidence 31 Activity

Activity

MIC
Antiviral
0.5-2 µM

Target

Escherichia coli ATCC 25922 or ML35 or D21

Source & Reference

DRAMP DRAVP 2.0

Other

Source Activity Label Source Definition
Antiviral
DRAMP antiviral activity supported by activity records against viral targets.
Active against E. coli ATCC 25922 or ML35 or D21 (MIC 0.5-2 uM), S. typhimurium ATCC 14028 (MIC 8 uM), P. aeruginosa ATCC 27853 (MIC 4 uM), S. marcescens
Evidence 32 Activity

Activity

MIC
Antiviral
8 µM

Target

S. typhimurium ATCC 14028

Source & Reference

DRAMP DRAVP 2.0

Other

Active against E. coli ATCC 25922 or ML35 or D21 (MIC 0.5-2 uM), S. typhimurium ATCC 14028 (MIC 8 uM), P. aeruginosa ATCC 27853 (MIC 4 uM), S. marcescens ATCC 8100 (MIC 4 uM), P-vulgaris ATCC
Evidence 33 Activity

Activity

MIC
Antiviral
4 µM

Target

Pseudomonas aeruginosa ATCC 27853

Source & Reference

DRAMP DRAVP 2.0

Other

t E. coli ATCC 25922 or ML35 or D21 (MIC 0.5-2 uM), S. typhimurium ATCC 14028 (MIC 8 uM), P. aeruginosa ATCC 27853 (MIC 4 uM), S. marcescens ATCC 8100 (MIC 4 uM), P-vulgaris ATCC 13315 (MIC>64 uM), S. aureus ATCC 25
Evidence 34 Activity

Activity

MIC
Antiviral
4 µM

Target

S. marcescens ATCC 8100

Source & Reference

DRAMP DRAVP 2.0

Other

MIC 0.5-2 uM), S. typhimurium ATCC 14028 (MIC 8 uM), P. aeruginosa ATCC 27853 (MIC 4 uM), S. marcescens ATCC 8100 (MIC 4 uM), P-vulgaris ATCC 13315 (MIC>64 uM), S. aureus ATCC 25923 or Cowan I MRSA (MIC 32-64 uM),
Evidence 35 Activity

Activity

MIC
Antiviral
32-64 µM

Target

Staphylococcus aureus ATCC 25923 or Cowan I MRSA

Source & Reference

DRAMP DRAVP 2.0

Other

27853 (MIC 4 uM), S. marcescens ATCC 8100 (MIC 4 uM), P-vulgaris ATCC 13315 (MIC>64 uM), S. aureus ATCC 25923 or Cowan I MRSA (MIC 32-64 uM), S. epidermidis ATCC 12228 (MIC 16 uM), S. faecalis ATCC 29212 (MIC 32 uM), B. megaterium
Evidence 36 Activity

Activity

MIC
Antiviral
16 µM

Target

Staphylococcus epidermidis ATCC 12228

Source & Reference

DRAMP DRAVP 2.0

Other

, P-vulgaris ATCC 13315 (MIC>64 uM), S. aureus ATCC 25923 or Cowan I MRSA (MIC 32-64 uM), S. epidermidis ATCC 12228 (MIC 16 uM), S. faecalis ATCC 29212 (MIC 32 uM), B. megaterium Bm11 (MIC 4 uM), fumgi C-albicans (MIC
Evidence 37 Activity

Activity

MIC
Antiviral
32 µM

Target

S. faecalis ATCC 29212

Source & Reference

DRAMP DRAVP 2.0

Other

aureus ATCC 25923 or Cowan I MRSA (MIC 32-64 uM), S. epidermidis ATCC 12228 (MIC 16 uM), S. faecalis ATCC 29212 (MIC 32 uM), B. megaterium Bm11 (MIC 4 uM), fumgi C-albicans (MIC > 64 uM), C. neoformans (MIC 16 uM)
Evidence 38 Activity

Activity

MIC
Antiviral
4 µM

Target

B. megaterium Bm11

Source & Reference

DRAMP DRAVP 2.0

Other

MIC 32-64 uM), S. epidermidis ATCC 12228 (MIC 16 uM), S. faecalis ATCC 29212 (MIC 32 uM), B. megaterium Bm11 (MIC 4 uM), fumgi C-albicans (MIC > 64 uM), C. neoformans (MIC 16 uM), and the single-stranded RNA v
Evidence 39 Activity

Activity

MIC
Antiviral
16 µM

Target

C. neoformans

Source & Reference

DRAMP DRAVP 2.0

Other

is ATCC 29212 (MIC 32 uM), B. megaterium Bm11 (MIC 4 uM), fumgi C-albicans (MIC > 64 uM), C. neoformans (MIC 16 uM), and the single-stranded RNA virus respiratory syncytial virus (RSV). It also inhibit B.
Evidence 40 Activity

Activity

MIC
Antiviral
8 µg/mL

Target

B. anthracis

Source & Reference

DRAMP DRAVP 2.0

Other

uM), and the single-stranded RNA virus respiratory syncytial virus (RSV). It also inhibit B. anthracis (MIC 8 ug/ml) ( Blower et al., 2018 ). IL-17A and IL-17F are essential for the production of CRAMP to c