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Peptide record

TPDB11428

Antibacterial Antifungal standard
33 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB11428
Antibacterial Antifungal
Anti-infective peptides
AntiBP3 Peptipedia AFP-GFuse Antifungipept CAFPdb dbAMP
standard
No
A 33-aa standard natural multi-activity (Antibacterial and Antifungal) peptide sequence curated from AntiBP3, Peptipedia, AFP-GFuse, and other sources, with an available 3D structural model.
Sequence
SFLSTFKKLAIDAAKNAGQSVLHTLTCKLDNQC
Physicochemical Analysis
C156H257N43O48S2
REMPWY
L
3567.14
9.05
5
2
13
+2
3.74
0.024
91.82
Mammalian: 1.9 hour Yeast: >20 hour E.coli: >10 hour
125
3.50
12
Residue Composition
number
4
A
0
R
2
N
2
D
2
C
0
E
2
Q
1
G
1
H
1
I
5
L
4
K
0
M
2
F
0
P
3
S
3
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 4 R: 0 N: 2 D: 2 C: 2 E: 0 Q: 2 G: 1 H: 1 I: 1 L: 5 K: 4 M: 0 F: 2 P: 0 S: 3 T: 3 W: 0 Y: 0 V: 1
Chemical Descriptors
33
C156H257N43O48S2
3567.14
9.05
+2
3.74
0.024
Evidence Records 20 records
Evidence 1 Activity

Activity

MIC
Antibacterial
10 µg/mL

Target

Staphylococcus aureus ATCC25923

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
Active against S. aureus ATCC25923 (MIC 10 ug/ml), S. aureus IS10# (MIC 5 ug/ml), S. aureus IS37# (MIC 10 ug/ml), E. faecalis ATCC29212 (MI
Evidence 2 Activity

Activity

MIC
Antibacterial
10 µg/mL

Target

Enterococcus faecalis ATCC29212

Source & Reference

dbAMP

Other

ATCC25923 (MIC 10 ug/ml), S. aureus IS10# (MIC 5 ug/ml), S. aureus IS37# (MIC 10 ug/ml), E. faecalis ATCC29212 (MIC 10 ug/ml), E. coli ATCC25922 (MIC 5 ug/ml), E. coli IS37# (MIC 10 ug/ml), E. coli IS117# (MIC 10 ug
Evidence 3 Activity

Activity

MIC
Antibacterial
5 µg/mL

Target

Escherichia coli ATCC25922

Source & Reference

dbAMP

Other

S10# (MIC 5 ug/ml), S. aureus IS37# (MIC 10 ug/ml), E. faecalis ATCC29212 (MIC 10 ug/ml), E. coli ATCC25922 (MIC 5 ug/ml), E. coli IS37# (MIC 10 ug/ml), E. coli IS117# (MIC 10 ug/ml), E. coli IS218# (MIC 20 ug/m
Evidence 4 Activity

Activity

MIC
Antibacterial
1 µg/mL

Target

Klebsiella pneumoniae ATCC700603

Source & Reference

dbAMP

Other

IS117# (MIC 10 ug/ml), E. coli IS218# (MIC 20 ug/ml), E. cloacae ATCC13047 (MIC 5 and 5), K. pneumoniae ATCC700603 (MIC 1 ug/ml), K. pneumoniae IS 59# (MIC 20 ug/ml), B. dysenteriae (MIC 10 ug/ml), B. pyocyaneus CMCCB1
Evidence 5 Activity

Activity

MIC
Antibacterial
10 µg/mL

Target

B. dysenteriae

Source & Reference

dbAMP

Other

IC 5 and 5), K. pneumoniae ATCC700603 (MIC 1 ug/ml), K. pneumoniae IS 59# (MIC 20 ug/ml), B. dysenteriae (MIC 10 ug/ml), B. pyocyaneus CMCCB1010 (MIC 1 ug/ml), P. aeruginosa ATCC27853 (MIC 10 ug/ml), P. aerugi
Evidence 6 Activity

Activity

MIC
Antibacterial
1 µg/mL

Target

B. pyocyaneus CMCCB1010

Source & Reference

dbAMP

Other

700603 (MIC 1 ug/ml), K. pneumoniae IS 59# (MIC 20 ug/ml), B. dysenteriae (MIC 10 ug/ml), B. pyocyaneus CMCCB1010 (MIC 1 ug/ml), P. aeruginosa ATCC27853 (MIC 10 ug/ml), P. aeruginosa IS350# (MIC 20 ug/ml), C. albicans
Evidence 7 Activity

Activity

MIC
Antibacterial
10 µg/mL

Target

Pseudomonas aeruginosa ATCC27853

Source & Reference

dbAMP

Other

59# (MIC 20 ug/ml), B. dysenteriae (MIC 10 ug/ml), B. pyocyaneus CMCCB1010 (MIC 1 ug/ml), P. aeruginosa ATCC27853 (MIC 10 ug/ml), P. aeruginosa IS350# (MIC 20 ug/ml), C. albicans ATCC2002 (MIC 2 ug/ml), C. albicans ATC
Evidence 8 Activity

Activity

MIC
Antibacterial
2 µg/mL

Target

Candida albicans ATCC2002

Source & Reference

dbAMP

Other

IC 1 ug/ml), P. aeruginosa ATCC27853 (MIC 10 ug/ml), P. aeruginosa IS350# (MIC 20 ug/ml), C. albicans ATCC2002 (MIC 2 ug/ml), C. albicans ATCC90028 (MIC 2.5 ug/ml), C. parapsilosis ATCC22019 (MIC 5 ug/ml).
Evidence 9 Activity

Activity

MIC
Antibacterial
2.5 µg/mL

Target

Candida albicans ATCC90028

Source & Reference

dbAMP

Other

(MIC 10 ug/ml), P. aeruginosa IS350# (MIC 20 ug/ml), C. albicans ATCC2002 (MIC 2 ug/ml), C. albicans ATCC90028 (MIC 2.5 ug/ml), C. parapsilosis ATCC22019 (MIC 5 ug/ml).
Evidence 10 Activity

Activity

MIC
Antibacterial
5 µg/mL

Target

C. parapsilosis ATCC22019

Source & Reference

dbAMP

Other

MIC 20 ug/ml), C. albicans ATCC2002 (MIC 2 ug/ml), C. albicans ATCC90028 (MIC 2.5 ug/ml), C. parapsilosis ATCC22019 (MIC 5 ug/ml).
Evidence 11 Activity

Activity

MIC
Antifungal
10 µg/mL

Target

Staphylococcus aureus ATCC25923

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
Active against S. aureus ATCC25923 (MIC 10 ug/ml), S. aureus IS10# (MIC 5 ug/ml), S. aureus IS37# (MIC 10 ug/ml), E. faecalis ATCC29212 (MI
Evidence 12 Activity

Activity

MIC
Antifungal
10 µg/mL

Target

Enterococcus faecalis ATCC29212

Source & Reference

dbAMP CAFPdb Antifungipept

Other

ATCC25923 (MIC 10 ug/ml), S. aureus IS10# (MIC 5 ug/ml), S. aureus IS37# (MIC 10 ug/ml), E. faecalis ATCC29212 (MIC 10 ug/ml), E. coli ATCC25922 (MIC 5 ug/ml), E. coli IS37# (MIC 10 ug/ml), E. coli IS117# (MIC 10 ug
Evidence 13 Activity

Activity

MIC
Antifungal
5 µg/mL

Target

Escherichia coli ATCC25922

Source & Reference

dbAMP CAFPdb Antifungipept

Other

S10# (MIC 5 ug/ml), S. aureus IS37# (MIC 10 ug/ml), E. faecalis ATCC29212 (MIC 10 ug/ml), E. coli ATCC25922 (MIC 5 ug/ml), E. coli IS37# (MIC 10 ug/ml), E. coli IS117# (MIC 10 ug/ml), E. coli IS218# (MIC 20 ug/m
Evidence 14 Activity

Activity

MIC
Antifungal
1 µg/mL

Target

Klebsiella pneumoniae ATCC700603

Source & Reference

dbAMP CAFPdb Antifungipept

Other

IS117# (MIC 10 ug/ml), E. coli IS218# (MIC 20 ug/ml), E. cloacae ATCC13047 (MIC 5 and 5), K. pneumoniae ATCC700603 (MIC 1 ug/ml), K. pneumoniae IS 59# (MIC 20 ug/ml), B. dysenteriae (MIC 10 ug/ml), B. pyocyaneus CMCCB1
Evidence 15 Activity

Activity

MIC
Antifungal
10 µg/mL

Target

B. dysenteriae

Source & Reference

dbAMP CAFPdb Antifungipept

Other

IC 5 and 5), K. pneumoniae ATCC700603 (MIC 1 ug/ml), K. pneumoniae IS 59# (MIC 20 ug/ml), B. dysenteriae (MIC 10 ug/ml), B. pyocyaneus CMCCB1010 (MIC 1 ug/ml), P. aeruginosa ATCC27853 (MIC 10 ug/ml), P. aerugi
Evidence 16 Activity

Activity

MIC
Antifungal
1 µg/mL

Target

B. pyocyaneus CMCCB1010

Source & Reference

dbAMP CAFPdb Antifungipept

Other

700603 (MIC 1 ug/ml), K. pneumoniae IS 59# (MIC 20 ug/ml), B. dysenteriae (MIC 10 ug/ml), B. pyocyaneus CMCCB1010 (MIC 1 ug/ml), P. aeruginosa ATCC27853 (MIC 10 ug/ml), P. aeruginosa IS350# (MIC 20 ug/ml), C. albicans
Evidence 17 Activity

Activity

MIC
Antifungal
10 µg/mL

Target

Pseudomonas aeruginosa ATCC27853

Source & Reference

dbAMP CAFPdb Antifungipept

Other

59# (MIC 20 ug/ml), B. dysenteriae (MIC 10 ug/ml), B. pyocyaneus CMCCB1010 (MIC 1 ug/ml), P. aeruginosa ATCC27853 (MIC 10 ug/ml), P. aeruginosa IS350# (MIC 20 ug/ml), C. albicans ATCC2002 (MIC 2 ug/ml), C. albicans ATC
Evidence 18 Activity

Activity

MIC
Antifungal
2 µg/mL

Target

Candida albicans ATCC2002

Source & Reference

dbAMP CAFPdb Antifungipept

Other

IC 1 ug/ml), P. aeruginosa ATCC27853 (MIC 10 ug/ml), P. aeruginosa IS350# (MIC 20 ug/ml), C. albicans ATCC2002 (MIC 2 ug/ml), C. albicans ATCC90028 (MIC 2.5 ug/ml), C. parapsilosis ATCC22019 (MIC 5 ug/ml).
Evidence 19 Activity

Activity

MIC
Antifungal
2.5 µg/mL

Target

Candida albicans ATCC90028

Source & Reference

dbAMP CAFPdb Antifungipept

Other

(MIC 10 ug/ml), P. aeruginosa IS350# (MIC 20 ug/ml), C. albicans ATCC2002 (MIC 2 ug/ml), C. albicans ATCC90028 (MIC 2.5 ug/ml), C. parapsilosis ATCC22019 (MIC 5 ug/ml).
Evidence 20 Activity

Activity

MIC
Antifungal
5 µg/mL

Target

C. parapsilosis ATCC22019

Source & Reference

dbAMP CAFPdb Antifungipept

Other

MIC 20 ug/ml), C. albicans ATCC2002 (MIC 2 ug/ml), C. albicans ATCC90028 (MIC 2.5 ug/ml), C. parapsilosis ATCC22019 (MIC 5 ug/ml).