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Peptide record

TPDB11425

Antibacterial Toxicity standard
33 amino acids
Basic Information
3D PDB MODEL
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TPDB11425
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 dbAMP Peptipedia
standard
No
A 33-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3, dbAMP, and Peptipedia, with an available 3D structural model.
Sequence
AAAAAAAAAAGIGKFLHSAKKFGKAFVGEIMNS
Physicochemical Analysis
C144H230N40O39S1
RDCQPTWY
A
3177.71
10.55
5
1
20
+3
0.89
0.603
80.61
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
3
Residue Composition
number
12
A
0
R
1
N
0
D
0
C
1
E
0
Q
4
G
1
H
2
I
1
L
4
K
1
M
3
F
0
P
2
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 12 R: 0 N: 1 D: 0 C: 0 E: 1 Q: 0 G: 4 H: 1 I: 2 L: 1 K: 4 M: 1 F: 3 P: 0 S: 2 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
33
C144H230N40O39S1
3177.71
10.55
+3
0.89
0.603
Evidence Records 1 records
Evidence 1 Activity

Activity

9% Hemolysis
Toxicity
200 µg/mL
Hemolytic Cytotoxic
9% Hemolysis | 200 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Augmentation of the antibacterial activity of magainin by positive-charge chain extension. | Antimicrob Agents Chemother | 1992