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Peptide record

TPDB11409

Antibacterial Anticancer Antifungal Antiparasitic Antiviral standard
33 amino acids
Basic Information
3D PDB MODEL
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TPDB11409
Antibacterial Anticancer Antifungal Antiparasitic Antiviral
Anti-infective peptides Cancer-related peptides
AntiBP3 dbAMP DRAMP Peptipedia AFP-GFuse Antifungipept CAFPdb
standard
No
A 33-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
SFLSTFKELAINAAKNAGQSILHTLSCKLDKTC
Physicochemical Analysis
C156H258N42O48S2
RMPWYV
L
3554.14
9.05
5
2
13
+2
3.70
0.115
94.85
Mammalian: 1.9 hour Yeast: >20 hour E.coli: >10 hour
125
3.52
12
Residue Composition
number
4
A
0
R
2
N
1
D
2
C
1
E
1
Q
1
G
1
H
2
I
5
L
4
K
0
M
2
F
0
P
4
S
3
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 4 R: 0 N: 2 D: 1 C: 2 E: 1 Q: 1 G: 1 H: 1 I: 2 L: 5 K: 4 M: 0 F: 2 P: 0 S: 4 T: 3 W: 0 Y: 0 V: 0
Chemical Descriptors
33
C156H258N42O48S2
3554.14
9.05
+2
3.70
0.115
Evidence Records 12 records
Evidence 1 Activity

Activity

MIC
Antibacterial
20.4 µg/mL

Target

Escherichia coli

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class. DRAMP antibacterial activity supported by MIC records against bacterial target organisms.
Active against Gram- bacteria E. coli (MIC 20.4 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 20.4 ug/ml), Gram+ bacteria S. aureus (MIC
Evidence 2 Activity

Activity

MIC
Antibacterial
10.2 µg/mL

Target

Staphylococcus aureus

Source & Reference

dbAMP DRAMP

Other

IC 20.4 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 20.4 ug/ml), Gram+ bacteria S. aureus (MIC 10.2 ug/ml), and yeast C. albicans (MIC 5.1 ug/ml). Updated 7/2021
Evidence 3 Activity

Activity

MIC
Antibacterial
5.1 µg/mL

Target

Candida albicans

Source & Reference

dbAMP DRAMP

Other

led P. aeruginosa) (MIC 20.4 ug/ml), Gram+ bacteria S. aureus (MIC 10.2 ug/ml), and yeast C. albicans (MIC 5.1 ug/ml). Updated 7/2021
Evidence 4 Activity

Activity

MIC
Antifungal
20.4 µg/mL

Target

Escherichia coli

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class. DRAMP antifungal activity supported by activity records against fungal target organisms.
Active against Gram- bacteria E. coli (MIC 20.4 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 20.4 ug/ml), Gram+ bacteria S. aureus (MIC
Evidence 5 Activity

Activity

MIC
Antifungal
10.2 µg/mL

Target

Staphylococcus aureus

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

IC 20.4 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 20.4 ug/ml), Gram+ bacteria S. aureus (MIC 10.2 ug/ml), and yeast C. albicans (MIC 5.1 ug/ml). Updated 7/2021
Evidence 6 Activity

Activity

MIC
Antifungal
5.1 µg/mL

Target

Candida albicans

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

led P. aeruginosa) (MIC 20.4 ug/ml), Gram+ bacteria S. aureus (MIC 10.2 ug/ml), and yeast C. albicans (MIC 5.1 ug/ml). Updated 7/2021
Evidence 7 Activity

Activity

MIC
Antiparasitic
20.4 µg/mL

Target

Escherichia coli

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiparasitic
DRAMP antiparasitic activity supported by activity records against parasitic targets.
Active against Gram- bacteria E. coli (MIC 20.4 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 20.4 ug/ml), Gram+ bacteria S. aureus (MIC
Evidence 8 Activity

Activity

MIC
Antiparasitic
10.2 µg/mL

Target

Staphylococcus aureus

Source & Reference

DRAMP

Other

IC 20.4 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 20.4 ug/ml), Gram+ bacteria S. aureus (MIC 10.2 ug/ml), and yeast C. albicans (MIC 5.1 ug/ml). Updated 7/2021
Evidence 9 Activity

Activity

MIC
Antiparasitic
5.1 µg/mL

Target

Candida albicans

Source & Reference

DRAMP

Other

led P. aeruginosa) (MIC 20.4 ug/ml), Gram+ bacteria S. aureus (MIC 10.2 ug/ml), and yeast C. albicans (MIC 5.1 ug/ml). Updated 7/2021
Evidence 10 Activity

Activity

MIC
Antiviral
20.4 µg/mL

Target

Escherichia coli

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiviral
DRAMP antiviral activity supported by activity records against viral targets.
Active against Gram- bacteria E. coli (MIC 20.4 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 20.4 ug/ml), Gram+ bacteria S. aureus (MIC
Evidence 11 Activity

Activity

MIC
Antiviral
10.2 µg/mL

Target

Staphylococcus aureus

Source & Reference

DRAMP

Other

IC 20.4 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 20.4 ug/ml), Gram+ bacteria S. aureus (MIC 10.2 ug/ml), and yeast C. albicans (MIC 5.1 ug/ml). Updated 7/2021
Evidence 12 Activity

Activity

MIC
Antiviral
5.1 µg/mL

Target

Candida albicans

Source & Reference

DRAMP

Other

led P. aeruginosa) (MIC 20.4 ug/ml), Gram+ bacteria S. aureus (MIC 10.2 ug/ml), and yeast C. albicans (MIC 5.1 ug/ml). Updated 7/2021