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Peptide record

TPDB11408

Antibacterial Anticancer Antifungal Antiparasitic Antiviral standard
33 amino acids
Basic Information
3D PDB MODEL
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TPDB11408
Antibacterial Anticancer Antifungal Antiparasitic Antiviral
Anti-infective peptides Cancer-related peptides
AntiBP3 dbAMP DRAMP Peptipedia Antifungipept CAFPdb
standard
No
A 33-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
SFLDTLKNLAISAAKGAGQSVLSTLSCKLSKTC
Physicochemical Analysis
C145H251N39O47S2
REHMPWY
LS
3356.94
9.72
4
1
13
+3
1.52
0.385
103.64
Mammalian: 1.9 hour Yeast: >20 hour E.coli: >10 hour
125
3.72
13
Residue Composition
number
4
A
0
R
1
N
1
D
2
C
0
E
1
Q
2
G
0
H
1
I
6
L
4
K
0
M
1
F
0
P
6
S
3
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 4 R: 0 N: 1 D: 1 C: 2 E: 0 Q: 1 G: 2 H: 0 I: 1 L: 6 K: 4 M: 0 F: 1 P: 0 S: 6 T: 3 W: 0 Y: 0 V: 1
Chemical Descriptors
33
C145H251N39O47S2
3356.94
9.72
+3
1.52
0.385
Evidence Records 12 records
Evidence 1 Activity

Activity

MIC
Antibacterial
13.1 µg/mL

Target

Escherichia coli

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class. DRAMP antibacterial activity supported by MIC records against bacterial target organisms.
Active against Gram- bacteria E. coli (MIC 13.1 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 13.1 ug/ml), Gram+ bacteria S. aureus (MIC
Evidence 2 Activity

Activity

MIC
Antibacterial
13.1 µg/mL

Target

Staphylococcus aureus

Source & Reference

dbAMP DRAMP

Other

IC 13.1 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 13.1 ug/ml), Gram+ bacteria S. aureus (MIC 13.1 ug/ml), and yeast C. albicans (MIC 13.1 ug/ml). Found in multiple species. Also see Yang X et al
Evidence 3 Activity

Activity

MIC
Antibacterial
13.1 µg/mL

Target

Candida albicans

Source & Reference

dbAMP DRAMP

Other

led P. aeruginosa) (MIC 13.1 ug/ml), Gram+ bacteria S. aureus (MIC 13.1 ug/ml), and yeast C. albicans (MIC 13.1 ug/ml). Found in multiple species. Also see Yang X et al. 2012 J Proteome Res. J Proteome Res. 1
Evidence 4 Activity

Activity

MIC
Antifungal
13.1 µg/mL

Target

Escherichia coli

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class. DRAMP antifungal activity supported by activity records against fungal target organisms.
Active against Gram- bacteria E. coli (MIC 13.1 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 13.1 ug/ml), Gram+ bacteria S. aureus (MIC
Evidence 5 Activity

Activity

MIC
Antifungal
13.1 µg/mL

Target

Staphylococcus aureus

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

IC 13.1 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 13.1 ug/ml), Gram+ bacteria S. aureus (MIC 13.1 ug/ml), and yeast C. albicans (MIC 13.1 ug/ml). Found in multiple species. Also see Yang X et al
Evidence 6 Activity

Activity

MIC
Antifungal
13.1 µg/mL

Target

Candida albicans

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

led P. aeruginosa) (MIC 13.1 ug/ml), Gram+ bacteria S. aureus (MIC 13.1 ug/ml), and yeast C. albicans (MIC 13.1 ug/ml). Found in multiple species. Also see Yang X et al. 2012 J Proteome Res. J Proteome Res. 1
Evidence 7 Activity

Activity

MIC
Antiparasitic
13.1 µg/mL

Target

Escherichia coli

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiparasitic
DRAMP antiparasitic activity supported by activity records against parasitic targets.
Active against Gram- bacteria E. coli (MIC 13.1 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 13.1 ug/ml), Gram+ bacteria S. aureus (MIC
Evidence 8 Activity

Activity

MIC
Antiparasitic
13.1 µg/mL

Target

Staphylococcus aureus

Source & Reference

DRAMP

Other

IC 13.1 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 13.1 ug/ml), Gram+ bacteria S. aureus (MIC 13.1 ug/ml), and yeast C. albicans (MIC 13.1 ug/ml). Found in multiple species. Also see Yang X et al
Evidence 9 Activity

Activity

MIC
Antiparasitic
13.1 µg/mL

Target

Candida albicans

Source & Reference

DRAMP

Other

led P. aeruginosa) (MIC 13.1 ug/ml), Gram+ bacteria S. aureus (MIC 13.1 ug/ml), and yeast C. albicans (MIC 13.1 ug/ml). Found in multiple species. Also see Yang X et al. 2012 J Proteome Res. J Proteome Res. 1
Evidence 10 Activity

Activity

MIC
Antiviral
13.1 µg/mL

Target

Escherichia coli

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiviral
DRAMP antiviral activity supported by activity records against viral targets.
Active against Gram- bacteria E. coli (MIC 13.1 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 13.1 ug/ml), Gram+ bacteria S. aureus (MIC
Evidence 11 Activity

Activity

MIC
Antiviral
13.1 µg/mL

Target

Staphylococcus aureus

Source & Reference

DRAMP

Other

IC 13.1 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 13.1 ug/ml), Gram+ bacteria S. aureus (MIC 13.1 ug/ml), and yeast C. albicans (MIC 13.1 ug/ml). Found in multiple species. Also see Yang X et al
Evidence 12 Activity

Activity

MIC
Antiviral
13.1 µg/mL

Target

Candida albicans

Source & Reference

DRAMP

Other

led P. aeruginosa) (MIC 13.1 ug/ml), Gram+ bacteria S. aureus (MIC 13.1 ug/ml), and yeast C. albicans (MIC 13.1 ug/ml). Found in multiple species. Also see Yang X et al. 2012 J Proteome Res. J Proteome Res. 1