Back to search

Peptide record

TPDB11405

Antibacterial Anticancer Antifungal Antiparasitic standard
33 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB11405
Antibacterial Anticancer Antifungal Antiparasitic
Anti-infective peptides Cancer-related peptides
AntiBP3 dbAMP DRAMP Peptipedia AFP-GFuse Antifungipept CAFPdb
standard
No
A 33-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
VTCFCKRPVCDSGETQIGYCRLGNTFYRLCCRQ
Physicochemical Analysis
C161H255N49O47S6
AHMW
C
3821.46
8.31
5
2
9
+3
3.22
-0.200
53.03
Mammalian: 100 hour Yeast: >20 hour E.coli: >10 hour
3355
87.79
15
Residue Composition
number
0
A
4
R
1
N
1
D
6
C
1
E
2
Q
3
G
0
H
1
I
2
L
1
K
0
M
2
F
1
P
1
S
3
T
0
W
2
Y
2
V
Amino Acid Distribution
A: 0 R: 4 N: 1 D: 1 C: 6 E: 1 Q: 2 G: 3 H: 0 I: 1 L: 2 K: 1 M: 0 F: 2 P: 1 S: 1 T: 3 W: 0 Y: 2 V: 2
Chemical Descriptors
33
C161H255N49O47S6
3821.46
8.31
+3
3.22
-0.200
Evidence Records 24 records
Evidence 1 Activity

Activity

IC50
Antibacterial
6.5 µg/mL

Target

Staphylococcus aureus

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class. DRAMP antibacterial activity supported by MIC records against bacterial target organisms.
Active against S. aureus (IC50 6.5 ug/ml), S. pyogenes (IC50 5.9 ug/ml), E. faecalis (IC50 9.2 ug/ml), E. coli (IC50 11.8 ug/ml), S
Evidence 2 Activity

Activity

IC50
Antibacterial
5.9 µg/mL

Target

Streptococcus pyogenes

Source & Reference

dbAMP DRAMP

Other

Active against S. aureus (IC50 6.5 ug/ml), S. pyogenes (IC50 5.9 ug/ml), E. faecalis (IC50 9.2 ug/ml), E. coli (IC50 11.8 ug/ml), Salmonella serotype krefeld (IC
Evidence 3 Activity

Activity

IC50
Antibacterial
9.2 µg/mL

Target

Enterococcus faecalis

Source & Reference

dbAMP DRAMP

Other

Active against S. aureus (IC50 6.5 ug/ml), S. pyogenes (IC50 5.9 ug/ml), E. faecalis (IC50 9.2 ug/ml), E. coli (IC50 11.8 ug/ml), Salmonella serotype krefeld (IC50 9.8 ug/ml), K. oxytoca (IC5
Evidence 4 Activity

Activity

IC50
Antibacterial
11.8 µg/mL

Target

Escherichia coli

Source & Reference

dbAMP DRAMP

Other

t S. aureus (IC50 6.5 ug/ml), S. pyogenes (IC50 5.9 ug/ml), E. faecalis (IC50 9.2 ug/ml), E. coli (IC50 11.8 ug/ml), Salmonella serotype krefeld (IC50 9.8 ug/ml), K. oxytoca (IC50 13.1 ug/ml), P. aeruginos
Evidence 5 Activity

Activity

IC50
Antibacterial
13.1 µg/mL

Target

Klebsiella oxytoca

Source & Reference

dbAMP DRAMP

Other

IC50 9.2 ug/ml), E. coli (IC50 11.8 ug/ml), Salmonella serotype krefeld (IC50 9.8 ug/ml), K. oxytoca (IC50 13.1 ug/ml), P. aeruginosa (IC50 32.7 ug/ml), C. albicans (IC50 81.7 ug/ml), and C. neoformans (IC50
Evidence 6 Activity

Activity

IC50
Antibacterial
32.7 µg/mL

Target

Pseudomonas aeruginosa

Source & Reference

dbAMP DRAMP

Other

11.8 ug/ml), Salmonella serotype krefeld (IC50 9.8 ug/ml), K. oxytoca (IC50 13.1 ug/ml), P. aeruginosa (IC50 32.7 ug/ml), C. albicans (IC50 81.7 ug/ml), and C. neoformans (IC50 35.9 ug/ml). IC50: 50% inhibition
Evidence 7 Activity

Activity

IC50
Antibacterial
81.7 µg/mL

Target

Candida albicans

Source & Reference

dbAMP DRAMP

Other

krefeld (IC50 9.8 ug/ml), K. oxytoca (IC50 13.1 ug/ml), P. aeruginosa (IC50 32.7 ug/ml), C. albicans (IC50 81.7 ug/ml), and C. neoformans (IC50 35.9 ug/ml). IC50: 50% inhibition. UniProt P81468 : you can view
Evidence 8 Activity

Activity

IC50
Antibacterial
35.9 µg/mL

Target

C. neoformans

Source & Reference

dbAMP DRAMP

Other

ca (IC50 13.1 ug/ml), P. aeruginosa (IC50 32.7 ug/ml), C. albicans (IC50 81.7 ug/ml), and C. neoformans (IC50 35.9 ug/ml). IC50: 50% inhibition. UniProt P81468 : you can view AlphaFold predicted structure. Updat
Evidence 9 Activity

Activity

IC50
Antifungal
6.5 µg/mL

Target

Staphylococcus aureus

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class. DRAMP antifungal activity supported by activity records against fungal target organisms.
Active against S. aureus (IC50 6.5 ug/ml), S. pyogenes (IC50 5.9 ug/ml), E. faecalis (IC50 9.2 ug/ml), E. coli (IC50 11.8 ug/ml), S
Evidence 10 Activity

Activity

IC50
Antifungal
5.9 µg/mL

Target

Streptococcus pyogenes

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Active against S. aureus (IC50 6.5 ug/ml), S. pyogenes (IC50 5.9 ug/ml), E. faecalis (IC50 9.2 ug/ml), E. coli (IC50 11.8 ug/ml), Salmonella serotype krefeld (IC
Evidence 11 Activity

Activity

IC50
Antifungal
9.2 µg/mL

Target

Enterococcus faecalis

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Active against S. aureus (IC50 6.5 ug/ml), S. pyogenes (IC50 5.9 ug/ml), E. faecalis (IC50 9.2 ug/ml), E. coli (IC50 11.8 ug/ml), Salmonella serotype krefeld (IC50 9.8 ug/ml), K. oxytoca (IC5
Evidence 12 Activity

Activity

IC50
Antifungal
11.8 µg/mL

Target

Escherichia coli

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

t S. aureus (IC50 6.5 ug/ml), S. pyogenes (IC50 5.9 ug/ml), E. faecalis (IC50 9.2 ug/ml), E. coli (IC50 11.8 ug/ml), Salmonella serotype krefeld (IC50 9.8 ug/ml), K. oxytoca (IC50 13.1 ug/ml), P. aeruginos
Evidence 13 Activity

Activity

IC50
Antifungal
13.1 µg/mL

Target

Klebsiella oxytoca

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

IC50 9.2 ug/ml), E. coli (IC50 11.8 ug/ml), Salmonella serotype krefeld (IC50 9.8 ug/ml), K. oxytoca (IC50 13.1 ug/ml), P. aeruginosa (IC50 32.7 ug/ml), C. albicans (IC50 81.7 ug/ml), and C. neoformans (IC50
Evidence 14 Activity

Activity

IC50
Antifungal
32.7 µg/mL

Target

Pseudomonas aeruginosa

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

11.8 ug/ml), Salmonella serotype krefeld (IC50 9.8 ug/ml), K. oxytoca (IC50 13.1 ug/ml), P. aeruginosa (IC50 32.7 ug/ml), C. albicans (IC50 81.7 ug/ml), and C. neoformans (IC50 35.9 ug/ml). IC50: 50% inhibition
Evidence 15 Activity

Activity

IC50
Antifungal
81.7 µg/mL

Target

Candida albicans

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

krefeld (IC50 9.8 ug/ml), K. oxytoca (IC50 13.1 ug/ml), P. aeruginosa (IC50 32.7 ug/ml), C. albicans (IC50 81.7 ug/ml), and C. neoformans (IC50 35.9 ug/ml). IC50: 50% inhibition. UniProt P81468 : you can view
Evidence 16 Activity

Activity

IC50
Antifungal
35.9 µg/mL

Target

C. neoformans

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

ca (IC50 13.1 ug/ml), P. aeruginosa (IC50 32.7 ug/ml), C. albicans (IC50 81.7 ug/ml), and C. neoformans (IC50 35.9 ug/ml). IC50: 50% inhibition. UniProt P81468 : you can view AlphaFold predicted structure. Updat
Evidence 17 Activity

Activity

IC50
Antiparasitic
6.5 µg/mL

Target

Staphylococcus aureus

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiparasitic
DRAMP antiparasitic activity supported by activity records against parasitic targets.
Active against S. aureus (IC50 6.5 ug/ml), S. pyogenes (IC50 5.9 ug/ml), E. faecalis (IC50 9.2 ug/ml), E. coli (IC50 11.8 ug/ml), S
Evidence 18 Activity

Activity

IC50
Antiparasitic
5.9 µg/mL

Target

Streptococcus pyogenes

Source & Reference

DRAMP

Other

Active against S. aureus (IC50 6.5 ug/ml), S. pyogenes (IC50 5.9 ug/ml), E. faecalis (IC50 9.2 ug/ml), E. coli (IC50 11.8 ug/ml), Salmonella serotype krefeld (IC
Evidence 19 Activity

Activity

IC50
Antiparasitic
9.2 µg/mL

Target

Enterococcus faecalis

Source & Reference

DRAMP

Other

Active against S. aureus (IC50 6.5 ug/ml), S. pyogenes (IC50 5.9 ug/ml), E. faecalis (IC50 9.2 ug/ml), E. coli (IC50 11.8 ug/ml), Salmonella serotype krefeld (IC50 9.8 ug/ml), K. oxytoca (IC5
Evidence 20 Activity

Activity

IC50
Antiparasitic
11.8 µg/mL

Target

Escherichia coli

Source & Reference

DRAMP

Other

t S. aureus (IC50 6.5 ug/ml), S. pyogenes (IC50 5.9 ug/ml), E. faecalis (IC50 9.2 ug/ml), E. coli (IC50 11.8 ug/ml), Salmonella serotype krefeld (IC50 9.8 ug/ml), K. oxytoca (IC50 13.1 ug/ml), P. aeruginos
Evidence 21 Activity

Activity

IC50
Antiparasitic
13.1 µg/mL

Target

Klebsiella oxytoca

Source & Reference

DRAMP

Other

IC50 9.2 ug/ml), E. coli (IC50 11.8 ug/ml), Salmonella serotype krefeld (IC50 9.8 ug/ml), K. oxytoca (IC50 13.1 ug/ml), P. aeruginosa (IC50 32.7 ug/ml), C. albicans (IC50 81.7 ug/ml), and C. neoformans (IC50
Evidence 22 Activity

Activity

IC50
Antiparasitic
32.7 µg/mL

Target

Pseudomonas aeruginosa

Source & Reference

DRAMP

Other

11.8 ug/ml), Salmonella serotype krefeld (IC50 9.8 ug/ml), K. oxytoca (IC50 13.1 ug/ml), P. aeruginosa (IC50 32.7 ug/ml), C. albicans (IC50 81.7 ug/ml), and C. neoformans (IC50 35.9 ug/ml). IC50: 50% inhibition
Evidence 23 Activity

Activity

IC50
Antiparasitic
81.7 µg/mL

Target

Candida albicans

Source & Reference

DRAMP

Other

krefeld (IC50 9.8 ug/ml), K. oxytoca (IC50 13.1 ug/ml), P. aeruginosa (IC50 32.7 ug/ml), C. albicans (IC50 81.7 ug/ml), and C. neoformans (IC50 35.9 ug/ml). IC50: 50% inhibition. UniProt P81468 : you can view
Evidence 24 Activity

Activity

IC50
Antiparasitic
35.9 µg/mL

Target

C. neoformans

Source & Reference

DRAMP

Other

ca (IC50 13.1 ug/ml), P. aeruginosa (IC50 32.7 ug/ml), C. albicans (IC50 81.7 ug/ml), and C. neoformans (IC50 35.9 ug/ml). IC50: 50% inhibition. UniProt P81468 : you can view AlphaFold predicted structure. Updat