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Peptide record

TPDB11390

Antibacterial Toxicity standard
32 amino acids
Basic Information
3D PDB MODEL
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TPDB11390
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 32-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
RQIKIWFQNRRWGGQLGRRRHRRRPSRRRRHW
Physicochemical Analysis
C189H307N83O38
ADCEMTYV
R
4350.05
13.48
16
0
7
+14
8.35
-2.297
36.56
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
16500
379.31
5
Residue Composition
number
0
A
13
R
1
N
0
D
0
C
0
E
3
Q
3
G
2
H
2
I
1
L
1
K
0
M
1
F
1
P
1
S
0
T
3
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 13 N: 1 D: 0 C: 0 E: 0 Q: 3 G: 3 H: 2 I: 2 L: 1 K: 1 M: 0 F: 1 P: 1 S: 1 T: 0 W: 3 Y: 0 V: 0
Chemical Descriptors
32
C189H307N83O38
4350.05
13.48
+14
8.35
-2.297
Evidence Records 2 records
Evidence 1 Activity

Activity

25% Killing
Toxicity
50 µM
Cytotoxic
25% Killing | 50 | µM | target cell: Human keratinocytes HaCat

Target

Human keratinocytes HaCat

Source & Reference

NA
DBAASP
HEXIM1 Peptide Exhibits Antimicrobial Activity Against Antibiotic Resistant Bacteria Through Guidance of Cell Penetrating Peptide. | Front Microbiol | 2019
Evidence 2 Activity

Activity

90% Killing
Toxicity
100 µM
Cytotoxic
90% Killing | 100 | µM | target cell: Human keratinocytes HaCat

Target

Human keratinocytes HaCat

Source & Reference

NA
DBAASP
HEXIM1 Peptide Exhibits Antimicrobial Activity Against Antibiotic Resistant Bacteria Through Guidance of Cell Penetrating Peptide. | Front Microbiol | 2019