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Peptide record

TPDB11377

Antibacterial Anticancer Antifungal Antiparasitic Antiviral Hemolysis Toxicity standard
32 amino acids
Basic Information
3D PDB MODEL
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TPDB11377
Antibacterial Anticancer Antifungal Antiparasitic Antiviral Hemolysis Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP Peptipedia Antifungipept CAFPdb AVPpred-BWR APD_complete HemoPI Hemolytic2 PD_Hemolysis ToxinPred 3.0
standard
No
A 32-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, Peptipedia, and other sources, with an available 3D structural model.
Sequence
GILDTFKGVAKGVAKDLAVHMLENLKCKMTGC
Physicochemical Analysis
C148H252N40O42S4
RQPSWY
K
3392.11
9.02
6
3
14
+2
6.21
0.300
97.50
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
125
3.69
5
Residue Composition
number
3
A
0
R
1
N
2
D
2
C
1
E
0
Q
4
G
1
H
1
I
4
L
5
K
2
M
1
F
0
P
0
S
2
T
0
W
0
Y
3
V
Amino Acid Distribution
A: 3 R: 0 N: 1 D: 2 C: 2 E: 1 Q: 0 G: 4 H: 1 I: 1 L: 4 K: 5 M: 2 F: 1 P: 0 S: 0 T: 2 W: 0 Y: 0 V: 3
Chemical Descriptors
32
C148H252N40O42S4
3392.11
9.02
+2
6.21
0.300
Evidence Records 2 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
>100 µM
Hemolytic Cytotoxic
50% Hemolysis | >100 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Host defense peptides in skin secretions of the Oregon spotted frog Rana pretiosa: implications for species resistance to chytridiomycosis. | Dev Comp Immunol | 2011
Evidence 2 Hemolysis

Source & Reference

APD_complete HemoPI PD_Hemolysis
APD_complete PD_Hemolysis

Other

Source Activity Label Source Definition
Hemolysis
APD_complete APD-derived hemolytic peptide annotation.