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Peptide record

TPDB11375

Antibacterial Anticancer Antifungal Antiparasitic Antiviral Toxicity standard
32 amino acids
Basic Information
3D PDB MODEL
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TPDB11375
Antibacterial Anticancer Antifungal Antiparasitic Antiviral Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP pep-lab Peptipedia ACP740 _ACP240 Antifungipept CAFPdb AI4AVP dbAMP 3.0 DRAVP 2.0 ToxinPred 3.0
standard
No
A 32-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
VTCYCRRTRCGFRERLSGACGYRGRIYRLCCR
Physicochemical Analysis
C158H261N59O41S6
NDQHKMPW
R
3835.54
10.02
9
1
9
+8
2.84
-0.494
48.75
Mammalian: 100 hour Yeast: >20 hour E.coli: >10 hour
4845
126.32
12
Residue Composition
number
1
A
9
R
0
N
0
D
6
C
1
E
0
Q
4
G
0
H
1
I
2
L
0
K
0
M
1
F
0
P
1
S
2
T
0
W
3
Y
1
V
Amino Acid Distribution
A: 1 R: 9 N: 0 D: 0 C: 6 E: 1 Q: 0 G: 4 H: 0 I: 1 L: 2 K: 0 M: 0 F: 1 P: 0 S: 1 T: 2 W: 0 Y: 3 V: 1
Chemical Descriptors
32
C158H261N59O41S6
3835.54
10.02
+8
2.84
-0.494
Evidence Records 5 records
Evidence 1 Activity

Activity

Antibacterial

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
Active against E. coli ML-35, S. typhimurium LT2, P. aeruginosa mucoid and nonmucoid strains, K. pneumoniae 8N3, 277, Chedid, S. aureus 502A, and C. albicans 820. Updated 7/2021
Evidence 2 Activity

Activity

Antifungal

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
Active against E. coli ML-35, S. typhimurium LT2, P. aeruginosa mucoid and nonmucoid strains, K. pneumoniae 8N3, 277, Chedid, S. aureus 502A, and C. albicans 820. Updated 7/2021
Evidence 3 Activity

Activity

Antiparasitic

Source & Reference

dbAMP 3.0 DRAMP

Other

Source Activity Label Source Definition
Antiparasitic
dbAMP 3.0 classified under the Anti-parasitic function class.
Active against E. coli ML-35, S. typhimurium LT2, P. aeruginosa mucoid and nonmucoid strains, K. pneumoniae 8N3, 277, Chedid, S. aureus 502A, and C. albicans 820. Updated 7/2021
Evidence 4 Activity

Activity

Antiviral

Source & Reference

dbAMP 3.0 DRAMP DRAVP 2.0

Other

Source Activity Label Source Definition
Antiviral
dbAMP 3.0 classified under the Anti-viral function class.
Active against E. coli ML-35, S. typhimurium LT2, P. aeruginosa mucoid and nonmucoid strains, K. pneumoniae 8N3, 277, Chedid, S. aureus 502A, and C. albicans 820. Updated 7/2021
Evidence 5 Activity

Activity

5% Hemolysis
Toxicity
>128 µM
Hemolytic Cytotoxic
5% Hemolysis | >128 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Characterization of bactericidal efficiency, cell selectivity, and mechanism of short interspecific hybrid peptides. | Amino Acids | 2018