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Peptide record

TPDB11374

Antibacterial Anticancer Antifungal Antiparasitic Antiviral Toxicity standard
32 amino acids
Basic Information
3D PDB MODEL
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TPDB11374
Antibacterial Anticancer Antifungal Antiparasitic Antiviral Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia Antifungipept ToxinPred 3.0
standard
No
A 32-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
GMWSKIKNAGKAAKAAAKAAGKAALGAVSEAM
Physicochemical Analysis
C133H228N40O38S2
RDCQHFPTY
A
3059.64
10.82
6
1
18
+5
3.53
0.106
70.94
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
5500
179.76
3
Residue Composition
number
12
A
0
R
1
N
0
D
0
C
1
E
0
Q
4
G
0
H
1
I
1
L
6
K
2
M
0
F
0
P
2
S
0
T
1
W
0
Y
1
V
Amino Acid Distribution
A: 12 R: 0 N: 1 D: 0 C: 0 E: 1 Q: 0 G: 4 H: 0 I: 1 L: 1 K: 6 M: 2 F: 0 P: 0 S: 2 T: 0 W: 1 Y: 0 V: 1
Chemical Descriptors
32
C133H228N40O38S2
3059.64
10.82
+5
3.53
0.106
Evidence Records 2 records
Evidence 1 Activity

Activity

Toxicity
Hemolytic Cytotoxic
- | NA | target cell: Rat erythrocytes

Target

Rat erythrocytes

Source & Reference

NA
DBAASP
Dermaseptin DA4, although closely related to dermaseptin B2, presents chemotactic and Gram-negative selective bactericidal activities. | FEBS J | 2009
Evidence 2 Activity

Activity

Toxicity
Hemolytic
Hemolytic_activity: [Ref. FEBS J. 2009 Nov 276(22):6773-6786.]Show no hemolytic activity against rat blood cells.

Target

erythrocytes

Source & Reference

NA
DRAMP
FEBS J. 2009 Nov 276(22):6773-6786.