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Peptide record

TPDB11373

Antibacterial Anticancer Antifungal Antiparasitic Toxicity standard
32 amino acids
Basic Information
3D PDB MODEL
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TPDB11373
Antibacterial Anticancer Antifungal Antiparasitic Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia AFP-GFuse Antifungipept CAFPdb ToxinPred 3.0
standard
No
A 32-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
QLKVDLWGTRSGIQPEQHSSGKSDVRRWRSRY
Physicochemical Analysis
C165H262N56O49
ANCMF
RS
3814.24
11.29
8
3
8
+4
8.55
-1.394
54.69
Mammalian: 0.8 hour Yeast: 10 min E.coli: >10 hour
12490
327.46
10
Residue Composition
number
0
A
5
R
0
N
2
D
0
C
1
E
3
Q
3
G
1
H
1
I
2
L
2
K
0
M
0
F
1
P
5
S
1
T
2
W
1
Y
2
V
Amino Acid Distribution
A: 0 R: 5 N: 0 D: 2 C: 0 E: 1 Q: 3 G: 3 H: 1 I: 1 L: 2 K: 2 M: 0 F: 0 P: 1 S: 5 T: 1 W: 2 Y: 1 V: 2
Chemical Descriptors
32
C165H262N56O49
3814.24
11.29
+4
8.55
-1.394
Evidence Records 3 records
Evidence 1 Activity

Activity

Toxicity
Hemolytic Cytotoxic
- | NA | target cell: Rabbit erythrocytes

Target

Rabbit erythrocytes

Source & Reference

NA
DBAASP
Purification and cloning of a novel antimicrobial peptide from salivary glands of the hard tick, Ixodes sinensis. | Comp Biochem Physiol B Biochem Mol Biol | 2008
Evidence 2 Activity

Activity

Toxicity
Hemolytic Cytotoxic
- | NA | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Structure-activity relationship of potent antimicrobial peptide analogs of Ixosin-B amide. | Bioorg Med Chem Lett | 2013
Evidence 3 Activity

Activity

Toxicity
Hemolytic
Hemolytic_activity: [Ref.18295522]Little hemolytic activity on rabbit red blood cells up to 200 µg/mL

Target

erythrocytes

Source & Reference

NA
DRAMP
Comp Biochem Physiol B Biochem Mol Biol. 2008 Apr 149(4):557-561.