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Peptide record

TPDB11364

Antibacterial Antifungal Antiparasitic Toxicity standard
32 amino acids
Basic Information
3D PDB MODEL
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TPDB11364
Antibacterial Antifungal Antiparasitic Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia Antifungipept dbAMP 3.0 i2APP ToxinPred 3.0
standard
No
A 32-aa standard natural multi-activity (Antibacterial, Antifungal, Antiparasitic, and other sources) peptide sequence curated from AntiBP3, Peptipedia, Antifungipept, and other sources, with an available 3D structural model.
Sequence
GVFDIIKGAGKQLIAHAMEKIAEKVGLNKDGN
Physicochemical Analysis
C149H250N42O44S1
RCPSTWY
GK
3365.94
9.60
6
4
14
+1
9.62
-0.103
103.75
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
3
Residue Composition
number
4
A
0
R
2
N
2
D
0
C
2
E
1
Q
5
G
1
H
4
I
2
L
5
K
1
M
1
F
0
P
0
S
0
T
0
W
0
Y
2
V
Amino Acid Distribution
A: 4 R: 0 N: 2 D: 2 C: 0 E: 2 Q: 1 G: 5 H: 1 I: 4 L: 2 K: 5 M: 1 F: 1 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 2
Chemical Descriptors
32
C149H250N42O44S1
3365.94
9.60
+1
9.62
-0.103
Evidence Records 5 records
Evidence 1 Activity

Activity

Antibacterial

Source & Reference

NA

Other

Originally discovered in 2015, it has leishmanicidal activity (IC50 12.7 uM) (Oliveira M et al., 2016) .
Evidence 2 Activity

Activity

Antifungal

Source & Reference

Antifungipept

Other

Originally discovered in 2015, it has leishmanicidal activity (IC50 12.7 uM) (Oliveira M et al., 2016) .
Evidence 3 Activity

Activity

Antiparasitic

Source & Reference

dbAMP 3.0

Other

Source Activity Label Source Definition
Antiparasitic
dbAMP 3.0 classified under the Anti-parasitic function class.
Originally discovered in 2015, it has leishmanicidal activity (IC50 12.7 uM) (Oliveira M et al., 2016) .
Evidence 4 Activity

Activity

0% Hemolysis
Toxicity
400 µg/mL
Hemolytic Cytotoxic
0% Hemolysis | 400 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Characterization and Biological Activities of Ocellatin Peptides from the Skin Secretion of the Frog Leptodactylus pustulatus. | J Nat Prod | 2015
Evidence 5 Activity

Activity

1% Hemolysis
Toxicity
800 µg/mL
Hemolytic Cytotoxic
1% Hemolysis | 800 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Characterization and Biological Activities of Ocellatin Peptides from the Skin Secretion of the Frog Leptodactylus pustulatus. | J Nat Prod | 2015