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Peptide record

TPDB11363

Antibacterial Antifungal standard
32 amino acids
Basic Information
3D PDB MODEL
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TPDB11363
Antibacterial Antifungal
Anti-infective peptides
AntiBP3 Peptipedia Antifungipept
standard
No
A 32-aa standard-residue multi-activity (Antibacterial and Antifungal) peptide sequence curated from AntiBP3, Peptipedia, and Antifungipept, with an available 3D structural model.
Sequence
FTCNSYACKAHCILQGHKSGSCARINLCKCQR
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C146H239N49O42S6
DEMPWV
C
3545.17
8.90
7
0
9
+5
1.73
-0.203
58.13
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
1865
0.53
15
Residue Composition
number
3
A
2
R
2
N
0
D
6
C
0
E
2
Q
2
G
2
H
2
I
2
L
3
K
0
M
1
F
0
P
3
S
1
T
0
W
1
Y
0
V
Amino Acid Distribution
A: 3 R: 2 N: 2 D: 0 C: 6 E: 0 Q: 2 G: 2 H: 2 I: 2 L: 2 K: 3 M: 0 F: 1 P: 0 S: 3 T: 1 W: 0 Y: 1 V: 0
Chemical Descriptors
32 reviewed residue count
C146H239N49O42S6 sequence-only estimate (linear, free termini)
3545.17 sequence-only estimate (linear, free termini)
8.90 sequence-only estimate (linear, free termini)
+5 sequence-only estimate (linear, free termini)
1.73 sequence-only estimate (linear, free termini)
-0.203 sequence-only estimate (linear, free termini)
Evidence Records 2 records
Evidence 1 Activity

Activity

MIC
Antibacterial
51.1 µM

Target

M. luteus

Source & Reference

NA

Other

Active against M. luteus (MIC 51.1 uM).
Evidence 2 Activity

Activity

MIC
Antifungal
51.1 µM

Target

M. luteus

Source & Reference

Antifungipept

Other

Active against M. luteus (MIC 51.1 uM).