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Peptide record

TPDB11362

Antibacterial Antifungal Toxicity standard
32 amino acids
Basic Information
3D PDB MODEL
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TPDB11362
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 dbAMP Peptipedia AFP-GFuse Antifungipept CAFPdb ToxinPred 3.0
standard
No
A 32-aa standard-residue multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from AntiBP3, dbAMP, Peptipedia, and other sources, with an available 3D structural model.
Sequence
IWDAIFHGAKHFLHRLVNPGGKDAVKDVQQKQ
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C167H258N50O43
CEMSTY
K
3654.19
10.16
8
3
13
+2
1.63
-0.553
85.31
Mammalian: 20 hour Yeast: 30 min E.coli: >10 hour
5500
1.51
4
Residue Composition
number
3
A
1
R
1
N
3
D
0
C
0
E
3
Q
3
G
3
H
2
I
2
L
4
K
0
M
2
F
1
P
0
S
0
T
1
W
0
Y
3
V
Amino Acid Distribution
A: 3 R: 1 N: 1 D: 3 C: 0 E: 0 Q: 3 G: 3 H: 3 I: 2 L: 2 K: 4 M: 0 F: 2 P: 1 S: 0 T: 0 W: 1 Y: 0 V: 3
Chemical Descriptors
32 reviewed residue count
C167H258N50O43 sequence-only estimate (linear, free termini)
3654.19 sequence-only estimate (linear, free termini)
10.16 sequence-only estimate (linear, free termini)
+2 sequence-only estimate (linear, free termini)
1.63 sequence-only estimate (linear, free termini)
-0.553 sequence-only estimate (linear, free termini)
Evidence Records 6 records
Evidence 1 Activity

Activity

MIC
Antibacterial
106 µM

Target

B.subtilis

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
Active against mainly C. albicans (40 uM) and very weakly against B.subtilis (MIC 106 uM), E.tarda (MIC 160 uM), and Vibrio sp. (MIC 106 uM). Updated 5/2017 8/2025.
Evidence 2 Activity

Activity

MIC
Antibacterial
160 µM

Target

E.tarda

Source & Reference

dbAMP

Other

ctive against mainly C. albicans (40 uM) and very weakly against B.subtilis (MIC 106 uM), E.tarda (MIC 160 uM), and Vibrio sp. (MIC 106 uM). Updated 5/2017 8/2025.
Evidence 3 Activity

Activity

MIC
Antifungal
106 µM

Target

B.subtilis

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
Active against mainly C. albicans (40 uM) and very weakly against B.subtilis (MIC 106 uM), E.tarda (MIC 160 uM), and Vibrio sp. (MIC 106 uM). Updated 5/2017 8/2025.
Evidence 4 Activity

Activity

MIC
Antifungal
160 µM

Target

E.tarda

Source & Reference

dbAMP CAFPdb Antifungipept

Other

ctive against mainly C. albicans (40 uM) and very weakly against B.subtilis (MIC 106 uM), E.tarda (MIC 160 uM), and Vibrio sp. (MIC 106 uM). Updated 5/2017 8/2025.
Evidence 5 Activity

Activity

0% Hemolysis
Toxicity
55 µM
Hemolytic Cytotoxic
0% Hemolysis | 55 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Cloning and functional characterization of three novel antimicrobial peptides from tilapia (Oreochromis niloticus). | Aquaculture | 2013
Evidence 6 Activity

Activity

0% Hemolysis
Toxicity
55 µM
Hemolytic Cytotoxic
0% Hemolysis | 55 | µM | target cell: Tilapia erythrocytes

Target

Tilapia erythrocytes

Source & Reference

NA
DBAASP
Cloning and functional characterization of three novel antimicrobial peptides from tilapia (Oreochromis niloticus). | Aquaculture | 2013