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Peptide record

TPDB11361

Chassatide C2 Antibacterial Anticancer Antifungal standard
32 amino acids
Basic Information
3D PDB MODEL
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TPDB11361
Chassatide C2
Antibacterial Anticancer Antifungal
Anti-infective peptides Cancer-related peptides
AntiBP3 dbAMP DRAMP Peptipedia ACP740 _ACP240 AntiCP 2.0 CancerPPD 2.0 SATPdb dbACP iACP-DRLF pep-lab Antifungipept
standard
No
A 32-aa standard-residue multi-activity (Antibacterial, Anticancer, and Antifungal) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
GIPCAESCVWIPPCTITALMGCSCKNNVCYNN
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C143H226N38O44S7
RDQHF
C
3406.02
5.90
1
1
11
-0
0.17
0.438
73.12
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
7365
2.16
15
Residue Composition
number
2
A
0
R
4
N
0
D
6
C
1
E
0
Q
2
G
0
H
3
I
1
L
1
K
1
M
0
F
3
P
2
S
2
T
1
W
1
Y
2
V
Amino Acid Distribution
A: 2 R: 0 N: 4 D: 0 C: 6 E: 1 Q: 0 G: 2 H: 0 I: 3 L: 1 K: 1 M: 1 F: 0 P: 3 S: 2 T: 2 W: 1 Y: 1 V: 2
Chemical Descriptors
32 reviewed residue count
C143H226N38O44S7 sequence-only estimate (linear, free termini)
3406.02 sequence-only estimate (linear, free termini)
5.90 sequence-only estimate (linear, free termini)
-0 sequence-only estimate (linear, free termini)
0.17 sequence-only estimate (linear, free termini)
0.438 sequence-only estimate (linear, free termini)
Free Activity
L Activity
Not Available Activity
Free Activity
Antibacterial Activity
Chassalia chartacea Activity
Evidence Records 3 records
Evidence 1 Activity

Activity

Antibacterial

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
Cancer: TOXIC TO HeLa cells.
Evidence 2 Activity

Activity

Not Available
Anticancer

Target

Not Available
Not Available
Not Available

Assay & Model

Not Available
Not Available

Source & Reference

CancerPPD 2.0 dbACP SATPdb
CancerPPD2
2012

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.
Evidence 3 Activity

Activity

Antifungal

Source & Reference

dbAMP DRAMP Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
Cancer: TOXIC TO HeLa cells.