TPDB11352

Evidence 1 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antibacterial

Activity Measurement 0.3 µM

Target

Target Organism Staphylococcus aureus ATCC 2592

Source & Reference

Database Source dbAMP

Other

Source Activity Label	Source Definition
Antibacterial	dbAMP classified as Antibacterial under the Anti-bacterial function class.

Evidence Text

Active against Gram+ S. aureus ATCC 2592 (MIC 0.3 uM), clinical strains (MIC 20.2 uM or >26.9 uM), S. epidermidis (MIC 2.5 uM), S. haemolyticus

Evidence 2 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antibacterial

Activity Measurement 2.5 µM

Target

Target Organism Staphylococcus epidermidis

Source & Reference

Database Source dbAMP

Other

Evidence Text

ainst Gram+ S. aureus ATCC 2592 (MIC 0.3 uM), clinical strains (MIC 20.2 uM or >26.9 uM), S. epidermidis (MIC 2.5 uM), S. haemolyticus IS 2401 or DRa (MIC 2.5 uM), N. asteroids, E. faecalis IS981 (MIC 1.3 uM

Evidence 3 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antibacterial

Activity Measurement 2.5 µM

Target

Target Organism Staphylococcus haemolyticus IS 2401 or DRa

Source & Reference

Database Source dbAMP

Other

Evidence Text

92 (MIC 0.3 uM), clinical strains (MIC 20.2 uM or >26.9 uM), S. epidermidis (MIC 2.5 uM), S. haemolyticus IS 2401 or DRa (MIC 2.5 uM), N. asteroids, E. faecalis IS981 (MIC 1.3 uM), E. faecium IS 1299 (MIC 2.5 uM), P. acnes

Evidence 4 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antibacterial

Activity Measurement 1.3 µM

Target

Target Organism Enterococcus faecalis IS981

Source & Reference

Database Source dbAMP

Other

Evidence Text

, S. epidermidis (MIC 2.5 uM), S. haemolyticus IS 2401 or DRa (MIC 2.5 uM), N. asteroids, E. faecalis IS981 (MIC 1.3 uM), E. faecium IS 1299 (MIC 2.5 uM), P. acnes (MIC 1.3 uM), Gram- K. oxytoca (MIC 2.5 uM), A

Evidence 5 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antibacterial

Activity Measurement 2.5 µM

Target

Target Organism E. faecium IS 1299

Source & Reference

Database Source dbAMP

Other

Evidence Text

. haemolyticus IS 2401 or DRa (MIC 2.5 uM), N. asteroids, E. faecalis IS981 (MIC 1.3 uM), E. faecium IS 1299 (MIC 2.5 uM), P. acnes (MIC 1.3 uM), Gram- K. oxytoca (MIC 2.5 uM), A. sobria, A. baumannii IS 2178 or

Evidence 6 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antibacterial

Activity Measurement 1.3 µM

Target

Target Organism P. acnes

Source & Reference

Database Source dbAMP

Other

Evidence Text

C 2.5 uM), N. asteroids, E. faecalis IS981 (MIC 1.3 uM), E. faecium IS 1299 (MIC 2.5 uM), P. acnes (MIC 1.3 uM), Gram- K. oxytoca (MIC 2.5 uM), A. sobria, A. baumannii IS 2178 or Drb (MIC 1.3 uM), A. b

Evidence 7 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antibacterial

Activity Measurement 2.5 µM

Target

Target Organism Klebsiella oxytoca

Source & Reference

Database Source dbAMP

Other

Evidence Text

aecalis IS981 (MIC 1.3 uM), E. faecium IS 1299 (MIC 2.5 uM), P. acnes (MIC 1.3 uM), Gram- K. oxytoca (MIC 2.5 uM), A. sobria, A. baumannii IS 2178 or Drb (MIC 1.3 uM), A. baumannii IS 2373 (MIC 2.5 uM),

Evidence 8 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antibacterial

Activity Measurement 1.3 µM

Target

Target Organism A. baumannii IS 2178 or Drb

Source & Reference

Database Source dbAMP

Other

Evidence Text

um IS 1299 (MIC 2.5 uM), P. acnes (MIC 1.3 uM), Gram- K. oxytoca (MIC 2.5 uM), A. sobria, A. baumannii IS 2178 or Drb (MIC 1.3 uM), A. baumannii IS 2373 (MIC 2.5 uM), S. maltophilia (MIC 0.6-1.3 uM), P. aeruginosa ATCC 2

Evidence 9 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antibacterial

Activity Measurement 2.5 µM

Target

Target Organism A. baumannii IS 2373

Source & Reference

Database Source dbAMP

Other

Evidence Text

uM), Gram- K. oxytoca (MIC 2.5 uM), A. sobria, A. baumannii IS 2178 or Drb (MIC 1.3 uM), A. baumannii IS 2373 (MIC 2.5 uM), S. maltophilia (MIC 0.6-1.3 uM), P. aeruginosa ATCC 27853, IS 1411-3 (MIC 10.1 uM), E. c

Evidence 10 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antibacterial

Activity Measurement 0.6-1.3 µM

Target

Target Organism Stenotrophomonas maltophilia

Source & Reference

Database Source dbAMP

Other

Evidence Text

, A. sobria, A. baumannii IS 2178 or Drb (MIC 1.3 uM), A. baumannii IS 2373 (MIC 2.5 uM), S. maltophilia (MIC 0.6-1.3 uM), P. aeruginosa ATCC 27853, IS 1411-3 (MIC 10.1 uM), E. coli ATCC 27853 IS 1334-5(MIC 1.3-

Evidence 11 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antibacterial

Activity Measurement 1.3-5.1 µM

Target

Target Organism Escherichia coli ATCC 27853 IS 1334-5

Source & Reference

Database Source dbAMP

Other

Evidence Text

uM), S. maltophilia (MIC 0.6-1.3 uM), P. aeruginosa ATCC 27853, IS 1411-3 (MIC 10.1 uM), E. coli ATCC 27853 IS 1334-5(MIC 1.3-5.1 uM), K. pneumoniae IS strains (MIC 1..3-5.1 uM), P. vulgaris (MIC 10.1 uM), P. mirabilis, S.

Evidence 12 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antibacterial

Activity Measurement 10.1 µM

Target

Target Organism P. vulgaris

Source & Reference

Database Source dbAMP

Other

Evidence Text

E. coli ATCC 27853 IS 1334-5(MIC 1.3-5.1 uM), K. pneumoniae IS strains (MIC 1..3-5.1 uM), P. vulgaris (MIC 10.1 uM), P. mirabilis, S. typhi IS 1408 (MIC 5.1 uM), fungi C. albicans ATCC 2002 (MIC 1.3 uM), C

Evidence 13 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antibacterial

Activity Measurement 5.1 µM

Target

Target Organism S. typhi IS 1408

Source & Reference

Database Source dbAMP

Other

Evidence Text

uM), K. pneumoniae IS strains (MIC 1..3-5.1 uM), P. vulgaris (MIC 10.1 uM), P. mirabilis, S. typhi IS 1408 (MIC 5.1 uM), fungi C. albicans ATCC 2002 (MIC 1.3 uM), C. glabrata IS 0902 (MIC 10.1 uM), and slime m

Evidence 14 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antibacterial

Activity Measurement 1.3 µM

Target

Target Organism Candida albicans ATCC 2002

Source & Reference

Database Source dbAMP

Other

Evidence Text

.3-5.1 uM), P. vulgaris (MIC 10.1 uM), P. mirabilis, S. typhi IS 1408 (MIC 5.1 uM), fungi C. albicans ATCC 2002 (MIC 1.3 uM), C. glabrata IS 0902 (MIC 10.1 uM), and slime mold (MIC 0.6 uM).

Evidence 15 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antibacterial

Activity Measurement 10.1 µM

Target

Target Organism C. glabrata IS 0902

Source & Reference

Database Source dbAMP

Other

Evidence Text

), P. mirabilis, S. typhi IS 1408 (MIC 5.1 uM), fungi C. albicans ATCC 2002 (MIC 1.3 uM), C. glabrata IS 0902 (MIC 10.1 uM), and slime mold (MIC 0.6 uM).

Evidence 16 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antifungal

Activity Measurement 0.3 µM

Target

Target Organism Staphylococcus aureus ATCC 2592

Source & Reference

Database Source dbAMP CAFPdb Antifungipept

Other

Source Activity Label	Source Definition
Antifungal	dbAMP classified under the Anti-fungal function class.

Evidence Text

Active against Gram+ S. aureus ATCC 2592 (MIC 0.3 uM), clinical strains (MIC 20.2 uM or >26.9 uM), S. epidermidis (MIC 2.5 uM), S. haemolyticus

Evidence 17 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antifungal

Activity Measurement 2.5 µM

Target

Target Organism Staphylococcus epidermidis

Source & Reference

Database Source dbAMP CAFPdb Antifungipept

Other

Evidence Text

ainst Gram+ S. aureus ATCC 2592 (MIC 0.3 uM), clinical strains (MIC 20.2 uM or >26.9 uM), S. epidermidis (MIC 2.5 uM), S. haemolyticus IS 2401 or DRa (MIC 2.5 uM), N. asteroids, E. faecalis IS981 (MIC 1.3 uM

Evidence 18 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antifungal

Activity Measurement 2.5 µM

Target

Target Organism Staphylococcus haemolyticus IS 2401 or DRa

Source & Reference

Database Source dbAMP CAFPdb Antifungipept

Other

Evidence Text

92 (MIC 0.3 uM), clinical strains (MIC 20.2 uM or >26.9 uM), S. epidermidis (MIC 2.5 uM), S. haemolyticus IS 2401 or DRa (MIC 2.5 uM), N. asteroids, E. faecalis IS981 (MIC 1.3 uM), E. faecium IS 1299 (MIC 2.5 uM), P. acnes

Evidence 19 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antifungal

Activity Measurement 1.3 µM

Target

Target Organism Enterococcus faecalis IS981

Source & Reference

Database Source dbAMP CAFPdb Antifungipept

Other

Evidence Text

, S. epidermidis (MIC 2.5 uM), S. haemolyticus IS 2401 or DRa (MIC 2.5 uM), N. asteroids, E. faecalis IS981 (MIC 1.3 uM), E. faecium IS 1299 (MIC 2.5 uM), P. acnes (MIC 1.3 uM), Gram- K. oxytoca (MIC 2.5 uM), A

Evidence 20 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antifungal

Activity Measurement 2.5 µM

Target

Target Organism E. faecium IS 1299

Source & Reference

Database Source dbAMP CAFPdb Antifungipept

Other

Evidence Text

. haemolyticus IS 2401 or DRa (MIC 2.5 uM), N. asteroids, E. faecalis IS981 (MIC 1.3 uM), E. faecium IS 1299 (MIC 2.5 uM), P. acnes (MIC 1.3 uM), Gram- K. oxytoca (MIC 2.5 uM), A. sobria, A. baumannii IS 2178 or

Evidence 21 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antifungal

Activity Measurement 1.3 µM

Target

Target Organism P. acnes

Source & Reference

Database Source dbAMP CAFPdb Antifungipept

Other

Evidence Text

C 2.5 uM), N. asteroids, E. faecalis IS981 (MIC 1.3 uM), E. faecium IS 1299 (MIC 2.5 uM), P. acnes (MIC 1.3 uM), Gram- K. oxytoca (MIC 2.5 uM), A. sobria, A. baumannii IS 2178 or Drb (MIC 1.3 uM), A. b

Evidence 22 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antifungal

Activity Measurement 2.5 µM

Target

Target Organism Klebsiella oxytoca

Source & Reference

Database Source dbAMP CAFPdb Antifungipept

Other

Evidence Text

aecalis IS981 (MIC 1.3 uM), E. faecium IS 1299 (MIC 2.5 uM), P. acnes (MIC 1.3 uM), Gram- K. oxytoca (MIC 2.5 uM), A. sobria, A. baumannii IS 2178 or Drb (MIC 1.3 uM), A. baumannii IS 2373 (MIC 2.5 uM),

Evidence 23 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antifungal

Activity Measurement 1.3 µM

Target

Target Organism A. baumannii IS 2178 or Drb

Source & Reference

Database Source dbAMP CAFPdb Antifungipept

Other

Evidence Text

um IS 1299 (MIC 2.5 uM), P. acnes (MIC 1.3 uM), Gram- K. oxytoca (MIC 2.5 uM), A. sobria, A. baumannii IS 2178 or Drb (MIC 1.3 uM), A. baumannii IS 2373 (MIC 2.5 uM), S. maltophilia (MIC 0.6-1.3 uM), P. aeruginosa ATCC 2

Evidence 24 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antifungal

Activity Measurement 2.5 µM

Target

Target Organism A. baumannii IS 2373

Source & Reference

Database Source dbAMP CAFPdb Antifungipept

Other

Evidence Text

uM), Gram- K. oxytoca (MIC 2.5 uM), A. sobria, A. baumannii IS 2178 or Drb (MIC 1.3 uM), A. baumannii IS 2373 (MIC 2.5 uM), S. maltophilia (MIC 0.6-1.3 uM), P. aeruginosa ATCC 27853, IS 1411-3 (MIC 10.1 uM), E. c

Evidence 25 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antifungal

Activity Measurement 0.6-1.3 µM

Target

Target Organism Stenotrophomonas maltophilia

Source & Reference

Database Source dbAMP CAFPdb Antifungipept

Other

Evidence Text

, A. sobria, A. baumannii IS 2178 or Drb (MIC 1.3 uM), A. baumannii IS 2373 (MIC 2.5 uM), S. maltophilia (MIC 0.6-1.3 uM), P. aeruginosa ATCC 27853, IS 1411-3 (MIC 10.1 uM), E. coli ATCC 27853 IS 1334-5(MIC 1.3-

Evidence 26 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antifungal

Activity Measurement 1.3-5.1 µM

Target

Target Organism Escherichia coli ATCC 27853 IS 1334-5

Source & Reference

Database Source dbAMP CAFPdb Antifungipept

Other

Evidence Text

uM), S. maltophilia (MIC 0.6-1.3 uM), P. aeruginosa ATCC 27853, IS 1411-3 (MIC 10.1 uM), E. coli ATCC 27853 IS 1334-5(MIC 1.3-5.1 uM), K. pneumoniae IS strains (MIC 1..3-5.1 uM), P. vulgaris (MIC 10.1 uM), P. mirabilis, S.

Evidence 27 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antifungal

Activity Measurement 10.1 µM

Target

Target Organism P. vulgaris

Source & Reference

Database Source dbAMP CAFPdb Antifungipept

Other

Evidence Text

E. coli ATCC 27853 IS 1334-5(MIC 1.3-5.1 uM), K. pneumoniae IS strains (MIC 1..3-5.1 uM), P. vulgaris (MIC 10.1 uM), P. mirabilis, S. typhi IS 1408 (MIC 5.1 uM), fungi C. albicans ATCC 2002 (MIC 1.3 uM), C

Evidence 28 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antifungal

Activity Measurement 5.1 µM

Target

Target Organism S. typhi IS 1408

Source & Reference

Database Source dbAMP CAFPdb Antifungipept

Other

Evidence Text

uM), K. pneumoniae IS strains (MIC 1..3-5.1 uM), P. vulgaris (MIC 10.1 uM), P. mirabilis, S. typhi IS 1408 (MIC 5.1 uM), fungi C. albicans ATCC 2002 (MIC 1.3 uM), C. glabrata IS 0902 (MIC 10.1 uM), and slime m

Evidence 29 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antifungal

Activity Measurement 1.3 µM

Target

Target Organism Candida albicans ATCC 2002

Source & Reference

Database Source dbAMP CAFPdb Antifungipept

Other

Evidence Text

.3-5.1 uM), P. vulgaris (MIC 10.1 uM), P. mirabilis, S. typhi IS 1408 (MIC 5.1 uM), fungi C. albicans ATCC 2002 (MIC 1.3 uM), C. glabrata IS 0902 (MIC 10.1 uM), and slime mold (MIC 0.6 uM).

Evidence 30 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antifungal

Activity Measurement 10.1 µM

Target

Target Organism C. glabrata IS 0902

Source & Reference

Database Source dbAMP CAFPdb Antifungipept

Other

Evidence Text

), P. mirabilis, S. typhi IS 1408 (MIC 5.1 uM), fungi C. albicans ATCC 2002 (MIC 1.3 uM), C. glabrata IS 0902 (MIC 10.1 uM), and slime mold (MIC 0.6 uM).

Evidence 31 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antiparasitic

Activity Measurement 0.3 µM

Target

Target Organism Staphylococcus aureus ATCC 2592

Source & Reference

Database Source NA

Other

Evidence Text

Active against Gram+ S. aureus ATCC 2592 (MIC 0.3 uM), clinical strains (MIC 20.2 uM or >26.9 uM), S. epidermidis (MIC 2.5 uM), S. haemolyticus

Evidence 32 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antiparasitic

Activity Measurement 2.5 µM

Target

Target Organism Staphylococcus epidermidis

Source & Reference

Database Source NA

Other

Evidence Text

ainst Gram+ S. aureus ATCC 2592 (MIC 0.3 uM), clinical strains (MIC 20.2 uM or >26.9 uM), S. epidermidis (MIC 2.5 uM), S. haemolyticus IS 2401 or DRa (MIC 2.5 uM), N. asteroids, E. faecalis IS981 (MIC 1.3 uM

Evidence 33 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antiparasitic

Activity Measurement 2.5 µM

Target

Target Organism Staphylococcus haemolyticus IS 2401 or DRa

Source & Reference

Database Source NA

Other

Evidence Text

92 (MIC 0.3 uM), clinical strains (MIC 20.2 uM or >26.9 uM), S. epidermidis (MIC 2.5 uM), S. haemolyticus IS 2401 or DRa (MIC 2.5 uM), N. asteroids, E. faecalis IS981 (MIC 1.3 uM), E. faecium IS 1299 (MIC 2.5 uM), P. acnes

Evidence 34 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antiparasitic

Activity Measurement 1.3 µM

Target

Target Organism Enterococcus faecalis IS981

Source & Reference

Database Source NA

Other

Evidence Text

, S. epidermidis (MIC 2.5 uM), S. haemolyticus IS 2401 or DRa (MIC 2.5 uM), N. asteroids, E. faecalis IS981 (MIC 1.3 uM), E. faecium IS 1299 (MIC 2.5 uM), P. acnes (MIC 1.3 uM), Gram- K. oxytoca (MIC 2.5 uM), A

Evidence 35 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antiparasitic

Activity Measurement 2.5 µM

Target

Target Organism E. faecium IS 1299

Source & Reference

Database Source NA

Other

Evidence Text

. haemolyticus IS 2401 or DRa (MIC 2.5 uM), N. asteroids, E. faecalis IS981 (MIC 1.3 uM), E. faecium IS 1299 (MIC 2.5 uM), P. acnes (MIC 1.3 uM), Gram- K. oxytoca (MIC 2.5 uM), A. sobria, A. baumannii IS 2178 or

Evidence 36 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antiparasitic

Activity Measurement 1.3 µM

Target

Target Organism P. acnes

Source & Reference

Database Source NA

Other

Evidence Text

C 2.5 uM), N. asteroids, E. faecalis IS981 (MIC 1.3 uM), E. faecium IS 1299 (MIC 2.5 uM), P. acnes (MIC 1.3 uM), Gram- K. oxytoca (MIC 2.5 uM), A. sobria, A. baumannii IS 2178 or Drb (MIC 1.3 uM), A. b

Evidence 37 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antiparasitic

Activity Measurement 2.5 µM

Target

Target Organism Klebsiella oxytoca

Source & Reference

Database Source NA

Other

Evidence Text

aecalis IS981 (MIC 1.3 uM), E. faecium IS 1299 (MIC 2.5 uM), P. acnes (MIC 1.3 uM), Gram- K. oxytoca (MIC 2.5 uM), A. sobria, A. baumannii IS 2178 or Drb (MIC 1.3 uM), A. baumannii IS 2373 (MIC 2.5 uM),

Evidence 38 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antiparasitic

Activity Measurement 1.3 µM

Target

Target Organism A. baumannii IS 2178 or Drb

Source & Reference

Database Source NA

Other

Evidence Text

um IS 1299 (MIC 2.5 uM), P. acnes (MIC 1.3 uM), Gram- K. oxytoca (MIC 2.5 uM), A. sobria, A. baumannii IS 2178 or Drb (MIC 1.3 uM), A. baumannii IS 2373 (MIC 2.5 uM), S. maltophilia (MIC 0.6-1.3 uM), P. aeruginosa ATCC 2

Evidence 39 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antiparasitic

Activity Measurement 2.5 µM

Target

Target Organism A. baumannii IS 2373

Source & Reference

Database Source NA

Other

Evidence Text

uM), Gram- K. oxytoca (MIC 2.5 uM), A. sobria, A. baumannii IS 2178 or Drb (MIC 1.3 uM), A. baumannii IS 2373 (MIC 2.5 uM), S. maltophilia (MIC 0.6-1.3 uM), P. aeruginosa ATCC 27853, IS 1411-3 (MIC 10.1 uM), E. c

Evidence 40 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antiparasitic

Activity Measurement 0.6-1.3 µM

Target

Target Organism Stenotrophomonas maltophilia

Source & Reference

Database Source NA

Other

Evidence Text

, A. sobria, A. baumannii IS 2178 or Drb (MIC 1.3 uM), A. baumannii IS 2373 (MIC 2.5 uM), S. maltophilia (MIC 0.6-1.3 uM), P. aeruginosa ATCC 27853, IS 1411-3 (MIC 10.1 uM), E. coli ATCC 27853 IS 1334-5(MIC 1.3-

Evidence 41 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antiparasitic

Activity Measurement 1.3-5.1 µM

Target

Target Organism Escherichia coli ATCC 27853 IS 1334-5

Source & Reference

Database Source NA

Other

Evidence Text

uM), S. maltophilia (MIC 0.6-1.3 uM), P. aeruginosa ATCC 27853, IS 1411-3 (MIC 10.1 uM), E. coli ATCC 27853 IS 1334-5(MIC 1.3-5.1 uM), K. pneumoniae IS strains (MIC 1..3-5.1 uM), P. vulgaris (MIC 10.1 uM), P. mirabilis, S.

Evidence 42 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antiparasitic

Activity Measurement 10.1 µM

Target

Target Organism P. vulgaris

Source & Reference

Database Source NA

Other

Evidence Text

E. coli ATCC 27853 IS 1334-5(MIC 1.3-5.1 uM), K. pneumoniae IS strains (MIC 1..3-5.1 uM), P. vulgaris (MIC 10.1 uM), P. mirabilis, S. typhi IS 1408 (MIC 5.1 uM), fungi C. albicans ATCC 2002 (MIC 1.3 uM), C

Evidence 43 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antiparasitic

Activity Measurement 5.1 µM

Target

Target Organism S. typhi IS 1408

Source & Reference

Database Source NA

Other

Evidence Text

uM), K. pneumoniae IS strains (MIC 1..3-5.1 uM), P. vulgaris (MIC 10.1 uM), P. mirabilis, S. typhi IS 1408 (MIC 5.1 uM), fungi C. albicans ATCC 2002 (MIC 1.3 uM), C. glabrata IS 0902 (MIC 10.1 uM), and slime m

Evidence 44 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antiparasitic

Activity Measurement 1.3 µM

Target

Target Organism Candida albicans ATCC 2002

Source & Reference

Database Source NA

Other

Evidence Text

.3-5.1 uM), P. vulgaris (MIC 10.1 uM), P. mirabilis, S. typhi IS 1408 (MIC 5.1 uM), fungi C. albicans ATCC 2002 (MIC 1.3 uM), C. glabrata IS 0902 (MIC 10.1 uM), and slime mold (MIC 0.6 uM).

Evidence 45 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antiparasitic

Activity Measurement 10.1 µM

Target

Target Organism C. glabrata IS 0902

Source & Reference

Database Source NA

Other

Evidence Text

), P. mirabilis, S. typhi IS 1408 (MIC 5.1 uM), fungi C. albicans ATCC 2002 (MIC 1.3 uM), C. glabrata IS 0902 (MIC 10.1 uM), and slime mold (MIC 0.6 uM).

Evidence 46 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antiviral

Activity Measurement 0.3 µM

Target

Target Organism Staphylococcus aureus ATCC 2592

Source & Reference

Database Source NA

Other

Evidence Text

Active against Gram+ S. aureus ATCC 2592 (MIC 0.3 uM), clinical strains (MIC 20.2 uM or >26.9 uM), S. epidermidis (MIC 2.5 uM), S. haemolyticus

Evidence 47 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antiviral

Activity Measurement 2.5 µM

Target

Target Organism Staphylococcus epidermidis

Source & Reference

Database Source NA

Other

Evidence Text

ainst Gram+ S. aureus ATCC 2592 (MIC 0.3 uM), clinical strains (MIC 20.2 uM or >26.9 uM), S. epidermidis (MIC 2.5 uM), S. haemolyticus IS 2401 or DRa (MIC 2.5 uM), N. asteroids, E. faecalis IS981 (MIC 1.3 uM

Evidence 48 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antiviral

Activity Measurement 2.5 µM

Target

Target Organism Staphylococcus haemolyticus IS 2401 or DRa

Source & Reference

Database Source NA

Other

Evidence Text

92 (MIC 0.3 uM), clinical strains (MIC 20.2 uM or >26.9 uM), S. epidermidis (MIC 2.5 uM), S. haemolyticus IS 2401 or DRa (MIC 2.5 uM), N. asteroids, E. faecalis IS981 (MIC 1.3 uM), E. faecium IS 1299 (MIC 2.5 uM), P. acnes

Evidence 49 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antiviral

Activity Measurement 1.3 µM

Target

Target Organism Enterococcus faecalis IS981

Source & Reference

Database Source NA

Other

Evidence Text

, S. epidermidis (MIC 2.5 uM), S. haemolyticus IS 2401 or DRa (MIC 2.5 uM), N. asteroids, E. faecalis IS981 (MIC 1.3 uM), E. faecium IS 1299 (MIC 2.5 uM), P. acnes (MIC 1.3 uM), Gram- K. oxytoca (MIC 2.5 uM), A

Evidence 50 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antiviral

Activity Measurement 2.5 µM

Target

Target Organism E. faecium IS 1299

Source & Reference

Database Source NA

Other

Evidence Text

. haemolyticus IS 2401 or DRa (MIC 2.5 uM), N. asteroids, E. faecalis IS981 (MIC 1.3 uM), E. faecium IS 1299 (MIC 2.5 uM), P. acnes (MIC 1.3 uM), Gram- K. oxytoca (MIC 2.5 uM), A. sobria, A. baumannii IS 2178 or

Evidence 51 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antiviral

Activity Measurement 1.3 µM

Target

Target Organism P. acnes

Source & Reference

Database Source NA

Other

Evidence Text

C 2.5 uM), N. asteroids, E. faecalis IS981 (MIC 1.3 uM), E. faecium IS 1299 (MIC 2.5 uM), P. acnes (MIC 1.3 uM), Gram- K. oxytoca (MIC 2.5 uM), A. sobria, A. baumannii IS 2178 or Drb (MIC 1.3 uM), A. b

Evidence 52 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antiviral

Activity Measurement 2.5 µM

Target

Target Organism Klebsiella oxytoca

Source & Reference

Database Source NA

Other

Evidence Text

aecalis IS981 (MIC 1.3 uM), E. faecium IS 1299 (MIC 2.5 uM), P. acnes (MIC 1.3 uM), Gram- K. oxytoca (MIC 2.5 uM), A. sobria, A. baumannii IS 2178 or Drb (MIC 1.3 uM), A. baumannii IS 2373 (MIC 2.5 uM),

Evidence 53 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antiviral

Activity Measurement 1.3 µM

Target

Target Organism A. baumannii IS 2178 or Drb

Source & Reference

Database Source NA

Other

Evidence Text

um IS 1299 (MIC 2.5 uM), P. acnes (MIC 1.3 uM), Gram- K. oxytoca (MIC 2.5 uM), A. sobria, A. baumannii IS 2178 or Drb (MIC 1.3 uM), A. baumannii IS 2373 (MIC 2.5 uM), S. maltophilia (MIC 0.6-1.3 uM), P. aeruginosa ATCC 2

Evidence 54 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antiviral

Activity Measurement 2.5 µM

Target

Target Organism A. baumannii IS 2373

Source & Reference

Database Source NA

Other

Evidence Text

uM), Gram- K. oxytoca (MIC 2.5 uM), A. sobria, A. baumannii IS 2178 or Drb (MIC 1.3 uM), A. baumannii IS 2373 (MIC 2.5 uM), S. maltophilia (MIC 0.6-1.3 uM), P. aeruginosa ATCC 27853, IS 1411-3 (MIC 10.1 uM), E. c

Evidence 55 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antiviral

Activity Measurement 0.6-1.3 µM

Target

Target Organism Stenotrophomonas maltophilia

Source & Reference

Database Source NA

Other

Evidence Text

, A. sobria, A. baumannii IS 2178 or Drb (MIC 1.3 uM), A. baumannii IS 2373 (MIC 2.5 uM), S. maltophilia (MIC 0.6-1.3 uM), P. aeruginosa ATCC 27853, IS 1411-3 (MIC 10.1 uM), E. coli ATCC 27853 IS 1334-5(MIC 1.3-

Evidence 56 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antiviral

Activity Measurement 1.3-5.1 µM

Target

Target Organism Escherichia coli ATCC 27853 IS 1334-5

Source & Reference

Database Source NA

Other

Evidence Text

uM), S. maltophilia (MIC 0.6-1.3 uM), P. aeruginosa ATCC 27853, IS 1411-3 (MIC 10.1 uM), E. coli ATCC 27853 IS 1334-5(MIC 1.3-5.1 uM), K. pneumoniae IS strains (MIC 1..3-5.1 uM), P. vulgaris (MIC 10.1 uM), P. mirabilis, S.

Evidence 57 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antiviral

Activity Measurement 10.1 µM

Target

Target Organism P. vulgaris

Source & Reference

Database Source NA

Other

Evidence Text

E. coli ATCC 27853 IS 1334-5(MIC 1.3-5.1 uM), K. pneumoniae IS strains (MIC 1..3-5.1 uM), P. vulgaris (MIC 10.1 uM), P. mirabilis, S. typhi IS 1408 (MIC 5.1 uM), fungi C. albicans ATCC 2002 (MIC 1.3 uM), C

Evidence 58 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antiviral

Activity Measurement 5.1 µM

Target

Target Organism S. typhi IS 1408

Source & Reference

Database Source NA

Other

Evidence Text

uM), K. pneumoniae IS strains (MIC 1..3-5.1 uM), P. vulgaris (MIC 10.1 uM), P. mirabilis, S. typhi IS 1408 (MIC 5.1 uM), fungi C. albicans ATCC 2002 (MIC 1.3 uM), C. glabrata IS 0902 (MIC 10.1 uM), and slime m

Evidence 59 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antiviral

Activity Measurement 1.3 µM

Target

Target Organism Candida albicans ATCC 2002

Source & Reference

Database Source NA

Other

Evidence Text

.3-5.1 uM), P. vulgaris (MIC 10.1 uM), P. mirabilis, S. typhi IS 1408 (MIC 5.1 uM), fungi C. albicans ATCC 2002 (MIC 1.3 uM), C. glabrata IS 0902 (MIC 10.1 uM), and slime mold (MIC 0.6 uM).

Evidence 60 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antiviral

Activity Measurement 10.1 µM

Target

Target Organism C. glabrata IS 0902

Source & Reference

Database Source NA

Other

Evidence Text

), P. mirabilis, S. typhi IS 1408 (MIC 5.1 uM), fungi C. albicans ATCC 2002 (MIC 1.3 uM), C. glabrata IS 0902 (MIC 10.1 uM), and slime mold (MIC 0.6 uM).

Evidence 61 Activity

Activity

Activity Endpoint 0% Hemolysis

Detail Source Activity Toxicity

Activity Measurement 50 µg/mL

Toxicity Type Hemolytic Cytotoxic

Toxicity Raw

0% Hemolysis | 50 | µg/mL | target cell: Human erythrocytes

Target

Target Cell Human erythrocytes

Source & Reference

Database Source NA

Source Database DBAASP

Reference

Gene cloning, expression and characterization of avian cathelicidin orthologs, Cc-CATHs, from Coturnix coturnix. | FEBS J | 2011

Evidence 62 Activity

Activity

Activity Endpoint 4% Hemolysis

Detail Source Activity Toxicity

Activity Measurement 100 µg/mL

Toxicity Type Hemolytic Cytotoxic

Toxicity Raw

4% Hemolysis | 100 | µg/mL | target cell: Human erythrocytes

Target

Target Cell Human erythrocytes

Source & Reference

Database Source NA

Source Database DBAASP

Reference

Gene cloning, expression and characterization of avian cathelicidin orthologs, Cc-CATHs, from Coturnix coturnix. | FEBS J | 2011

Evidence 63 Activity

Activity

Activity Endpoint IC50

Detail Source Activity Toxicity

Activity Measurement 75 µg/mL

Toxicity Type Cytotoxic

Toxicity Raw

IC50 | 75 | µg/mL | target cell: Human umbilical vein endothelial cells HUVEC

Target

Target Cell Human umbilical vein endothelial cells HUVEC

Source & Reference

Database Source NA

Source Database DBAASP

Reference

Gene cloning, expression and characterization of avian cathelicidin orthologs, Cc-CATHs, from Coturnix coturnix. | FEBS J | 2011

Evidence 64 Activity

Target

Target Organism Cutibacterium acnes

Source & Reference

Database Source DBAASP