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Peptide record

TPDB11351

Antibacterial Antifungal Hemolysis Toxicity standard
32 amino acids
Basic Information
3D PDB MODEL
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TPDB11351
Antibacterial Antifungal Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 dbAMP Peptipedia Antifungipept CAFPdb HemoPI Hemolytic2 PD_Hemolysis
standard
No
A 32-aa standard natural multi-activity (Antibacterial, Antifungal, Hemolysis, and other sources) peptide sequence curated from AntiBP3, dbAMP, Peptipedia, and other sources, with an available 3D structural model.
Sequence
RLYRRLYRRLYRRLYRRLYRRLYRRLYRRLYR
Physicochemical Analysis
C216H354N80O41
ANDCEQGHIKMFPSTWV
R
4727.70
12.30
16
0
16
+16
0.96
-1.625
97.50
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
11920
252.13
8
Residue Composition
number
0
A
16
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
8
L
0
K
0
M
0
F
0
P
0
S
0
T
0
W
8
Y
0
V
Amino Acid Distribution
A: 0 R: 16 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 8 K: 0 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 8 V: 0
Chemical Descriptors
32
C216H354N80O41
4727.70
12.30
+16
0.96
-1.625
Evidence Records 2 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
48 µM
Hemolytic Cytotoxic
50% Hemolysis | 48 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Antimicrobial dendrimeric peptides. | Eur J Biochem | 2002
Evidence 2 Hemolysis

Source & Reference

HemoPI PD_Hemolysis
PD_Hemolysis