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Peptide record

TPDB11350

Antibacterial Antifungal Antiparasitic Toxicity standard
32 amino acids
Basic Information
3D PDB MODEL
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TPDB11350
Antibacterial Antifungal Antiparasitic Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia Antifungipept dbAMP 3.0 ToxinPred 3.0
standard
No
A 32-aa standard natural multi-activity (Antibacterial, Antifungal, Antiparasitic, and other sources) peptide sequence curated from AntiBP3, Peptipedia, Antifungipept, and other sources, with an available 3D structural model.
Sequence
GVFDIIKGAGKQLIAHAMGKIAEKVGLNKDGN
Physicochemical Analysis
C146H246N42O42S1
RCPSTWY
G
3293.88
10.05
6
3
14
+2
7.61
-0.006
103.75
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
3
Residue Composition
number
4
A
0
R
2
N
2
D
0
C
1
E
1
Q
6
G
1
H
4
I
2
L
5
K
1
M
1
F
0
P
0
S
0
T
0
W
0
Y
2
V
Amino Acid Distribution
A: 4 R: 0 N: 2 D: 2 C: 0 E: 1 Q: 1 G: 6 H: 1 I: 4 L: 2 K: 5 M: 1 F: 1 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 2
Chemical Descriptors
32
C146H246N42O42S1
3293.88
10.05
+2
7.61
-0.006
Evidence Records 15 records
Evidence 1 Activity

Activity

MIC
Antibacterial
60 µM

Target

Escherichia coli ATCC 25922

Source & Reference

NA

Other

it has leishmanicidal activity (IC50 72.8 uM). Weakly active against E. coli ATCC 25922 (MIC 60 uM), K.pneumoniae ATCC 700603 (MIC >240 uM), S.choleraesuis ATCC 14028 (MIC 240 uM), and S.au
Evidence 2 Activity

Activity

MIC
Antibacterial
>240 µM

Target

K.pneumoniae ATCC 700603

Source & Reference

NA

Other

hmanicidal activity (IC50 72.8 uM). Weakly active against E. coli ATCC 25922 (MIC 60 uM), K.pneumoniae ATCC 700603 (MIC >240 uM), S.choleraesuis ATCC 14028 (MIC 240 uM), and S.aureus ATCC 29313 (MIC 240 uM).
Evidence 3 Activity

Activity

MIC
Antibacterial
240 µM

Target

S.choleraesuis ATCC 14028

Source & Reference

NA

Other

ly active against E. coli ATCC 25922 (MIC 60 uM), K.pneumoniae ATCC 700603 (MIC >240 uM), S.choleraesuis ATCC 14028 (MIC 240 uM), and S.aureus ATCC 29313 (MIC 240 uM).
Evidence 4 Activity

Activity

MIC
Antibacterial
240 µM

Target

S.aureus ATCC 29313

Source & Reference

NA

Other

uM), K.pneumoniae ATCC 700603 (MIC >240 uM), S.choleraesuis ATCC 14028 (MIC 240 uM), and S.aureus ATCC 29313 (MIC 240 uM).
Evidence 5 Activity

Activity

MIC
Antifungal
60 µM

Target

Escherichia coli ATCC 25922

Source & Reference

Antifungipept

Other

it has leishmanicidal activity (IC50 72.8 uM). Weakly active against E. coli ATCC 25922 (MIC 60 uM), K.pneumoniae ATCC 700603 (MIC >240 uM), S.choleraesuis ATCC 14028 (MIC 240 uM), and S.au
Evidence 6 Activity

Activity

MIC
Antifungal
>240 µM

Target

K.pneumoniae ATCC 700603

Source & Reference

Antifungipept

Other

hmanicidal activity (IC50 72.8 uM). Weakly active against E. coli ATCC 25922 (MIC 60 uM), K.pneumoniae ATCC 700603 (MIC >240 uM), S.choleraesuis ATCC 14028 (MIC 240 uM), and S.aureus ATCC 29313 (MIC 240 uM).
Evidence 7 Activity

Activity

MIC
Antifungal
240 µM

Target

S.choleraesuis ATCC 14028

Source & Reference

Antifungipept

Other

ly active against E. coli ATCC 25922 (MIC 60 uM), K.pneumoniae ATCC 700603 (MIC >240 uM), S.choleraesuis ATCC 14028 (MIC 240 uM), and S.aureus ATCC 29313 (MIC 240 uM).
Evidence 8 Activity

Activity

MIC
Antifungal
240 µM

Target

S.aureus ATCC 29313

Source & Reference

Antifungipept

Other

uM), K.pneumoniae ATCC 700603 (MIC >240 uM), S.choleraesuis ATCC 14028 (MIC 240 uM), and S.aureus ATCC 29313 (MIC 240 uM).
Evidence 9 Activity

Activity

MIC
Antiparasitic
60 µM

Target

Escherichia coli ATCC 25922

Source & Reference

dbAMP 3.0

Other

Source Activity Label Source Definition
Antiparasitic
dbAMP 3.0 classified under the Anti-parasitic function class.
it has leishmanicidal activity (IC50 72.8 uM). Weakly active against E. coli ATCC 25922 (MIC 60 uM), K.pneumoniae ATCC 700603 (MIC >240 uM), S.choleraesuis ATCC 14028 (MIC 240 uM), and S.au
Evidence 10 Activity

Activity

MIC
Antiparasitic
>240 µM

Target

K.pneumoniae ATCC 700603

Source & Reference

dbAMP 3.0

Other

hmanicidal activity (IC50 72.8 uM). Weakly active against E. coli ATCC 25922 (MIC 60 uM), K.pneumoniae ATCC 700603 (MIC >240 uM), S.choleraesuis ATCC 14028 (MIC 240 uM), and S.aureus ATCC 29313 (MIC 240 uM).
Evidence 11 Activity

Activity

MIC
Antiparasitic
240 µM

Target

S.choleraesuis ATCC 14028

Source & Reference

dbAMP 3.0

Other

ly active against E. coli ATCC 25922 (MIC 60 uM), K.pneumoniae ATCC 700603 (MIC >240 uM), S.choleraesuis ATCC 14028 (MIC 240 uM), and S.aureus ATCC 29313 (MIC 240 uM).
Evidence 12 Activity

Activity

MIC
Antiparasitic
240 µM

Target

S.aureus ATCC 29313

Source & Reference

dbAMP 3.0

Other

uM), K.pneumoniae ATCC 700603 (MIC >240 uM), S.choleraesuis ATCC 14028 (MIC 240 uM), and S.aureus ATCC 29313 (MIC 240 uM).
Evidence 13 Activity

Activity

0% Hemolysis
Toxicity
200 µg/mL
Hemolytic Cytotoxic
0% Hemolysis | 200 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Characterization and Biological Activities of Ocellatin Peptides from the Skin Secretion of the Frog Leptodactylus pustulatus. | J Nat Prod | 2015
Evidence 14 Activity

Activity

14% Hemolysis
Toxicity
800 µg/mL
Hemolytic Cytotoxic
14% Hemolysis | 800 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Characterization and Biological Activities of Ocellatin Peptides from the Skin Secretion of the Frog Leptodactylus pustulatus. | J Nat Prod | 2015
Evidence 15 Activity

Activity

Toxicity
Cytotoxic
- | NA | target cell: Mouse fibroblasts NIH 3T3

Target

Mouse fibroblasts NIH 3T3

Source & Reference

NA
DBAASP
Characterization and Biological Activities of Ocellatin Peptides from the Skin Secretion of the Frog Leptodactylus pustulatus. | J Nat Prod | 2015