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Peptide record

TPDB11336

Antibacterial Antifungal Toxicity standard
32 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB11336
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia AFP-GFuse Antifungipept CAFPdb dbAMP ToxinPred 3.0
standard
No
A 32-aa standard natural multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, AFP-GFuse, and other sources, with an available 3D structural model.
Sequence
VKVGINGFGRIGRLVTRAAFHGKKVEIVAIND
Physicochemical Analysis
C155H260N48O40
CQMPSWY
GV
3436.07
11.46
7
2
15
+4
6.42
0.272
115.62
Mammalian: 100 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
3
Residue Composition
number
3
A
3
R
2
N
1
D
0
C
1
E
0
Q
5
G
1
H
4
I
1
L
3
K
0
M
2
F
0
P
0
S
1
T
0
W
0
Y
5
V
Amino Acid Distribution
A: 3 R: 3 N: 2 D: 1 C: 0 E: 1 Q: 0 G: 5 H: 1 I: 4 L: 1 K: 3 M: 0 F: 2 P: 0 S: 0 T: 1 W: 0 Y: 0 V: 5
Chemical Descriptors
32
C155H260N48O40
3436.07
11.46
+4
6.42
0.272
Evidence Records 22 records
Evidence 1 Activity

Activity

MIC
Antibacterial
3.9-5.7 µg/mL

Target

B. subtilis

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
Active against B. subtilis (MIC 3.9-5.7 ug/ml), M. luteus (MIC 26 ug/ml), S. aureus (MIC 9.7 ug/ml), S. iniae (MIC 4.8 ug/ml), Gram- A.
Evidence 2 Activity

Activity

MIC
Antibacterial
26 µg/mL

Target

M. luteus

Source & Reference

dbAMP

Other

Active against B. subtilis (MIC 3.9-5.7 ug/ml), M. luteus (MIC 26 ug/ml), S. aureus (MIC 9.7 ug/ml), S. iniae (MIC 4.8 ug/ml), Gram- A. hydrophila (MIC 25 ug/ml),
Evidence 3 Activity

Activity

MIC
Antibacterial
9.7 µg/mL

Target

Staphylococcus aureus

Source & Reference

dbAMP

Other

Active against B. subtilis (MIC 3.9-5.7 ug/ml), M. luteus (MIC 26 ug/ml), S. aureus (MIC 9.7 ug/ml), S. iniae (MIC 4.8 ug/ml), Gram- A. hydrophila (MIC 25 ug/ml), E. coli D31 or ML35p or KC
Evidence 4 Activity

Activity

MIC
Antibacterial
4.8 µg/mL

Target

S. iniae

Source & Reference

dbAMP

Other

nst B. subtilis (MIC 3.9-5.7 ug/ml), M. luteus (MIC 26 ug/ml), S. aureus (MIC 9.7 ug/ml), S. iniae (MIC 4.8 ug/ml), Gram- A. hydrophila (MIC 25 ug/ml), E. coli D31 or ML35p or KCTC1116 (MIC 2.7-6.4 ug/ml)
Evidence 5 Activity

Activity

MIC
Antibacterial
25 µg/mL

Target

A. hydrophila

Source & Reference

dbAMP

Other

ml), M. luteus (MIC 26 ug/ml), S. aureus (MIC 9.7 ug/ml), S. iniae (MIC 4.8 ug/ml), Gram- A. hydrophila (MIC 25 ug/ml), E. coli D31 or ML35p or KCTC1116 (MIC 2.7-6.4 ug/ml), P. aeruginosa KCTC2004 (MIC 5.6 ug
Evidence 6 Activity

Activity

MIC
Antibacterial
2.7-6.4 µg/mL

Target

Escherichia coli D31 or ML35p or KCTC1116

Source & Reference

dbAMP

Other

S. aureus (MIC 9.7 ug/ml), S. iniae (MIC 4.8 ug/ml), Gram- A. hydrophila (MIC 25 ug/ml), E. coli D31 or ML35p or KCTC1116 (MIC 2.7-6.4 ug/ml), P. aeruginosa KCTC2004 (MIC 5.6 ug/ml), S. enterica KCTC2514 (MIC 2.0 ug/ml), S. flexner
Evidence 7 Activity

Activity

MIC
Antibacterial
5.6 µg/mL

Target

Pseudomonas aeruginosa KCTC2004

Source & Reference

dbAMP

Other

Gram- A. hydrophila (MIC 25 ug/ml), E. coli D31 or ML35p or KCTC1116 (MIC 2.7-6.4 ug/ml), P. aeruginosa KCTC2004 (MIC 5.6 ug/ml), S. enterica KCTC2514 (MIC 2.0 ug/ml), S. flexneri KCTC2517 (MIC 1.8 ug/ml), S. sonnei KC
Evidence 8 Activity

Activity

MIC
Antibacterial
2.0 µg/mL

Target

S. enterica KCTC2514

Source & Reference

dbAMP

Other

oli D31 or ML35p or KCTC1116 (MIC 2.7-6.4 ug/ml), P. aeruginosa KCTC2004 (MIC 5.6 ug/ml), S. enterica KCTC2514 (MIC 2.0 ug/ml), S. flexneri KCTC2517 (MIC 1.8 ug/ml), S. sonnei KCTC2009 (MIC 1.8 ug/ml), V. parahaemoly
Evidence 9 Activity

Activity

MIC
Antibacterial
1.8 µg/mL

Target

S. flexneri KCTC2517

Source & Reference

dbAMP

Other

6.4 ug/ml), P. aeruginosa KCTC2004 (MIC 5.6 ug/ml), S. enterica KCTC2514 (MIC 2.0 ug/ml), S. flexneri KCTC2517 (MIC 1.8 ug/ml), S. sonnei KCTC2009 (MIC 1.8 ug/ml), V. parahaemolyticus (MECs, 3.1-12.0 ug/mL), and C. a
Evidence 10 Activity

Activity

MIC
Antibacterial
1.8 µg/mL

Target

S. sonnei KCTC2009

Source & Reference

dbAMP

Other

C 5.6 ug/ml), S. enterica KCTC2514 (MIC 2.0 ug/ml), S. flexneri KCTC2517 (MIC 1.8 ug/ml), S. sonnei KCTC2009 (MIC 1.8 ug/ml), V. parahaemolyticus (MECs, 3.1-12.0 ug/mL), and C. albicans (16 ug/ml). It is bacteriost
Evidence 11 Activity

Activity

MIC
Antifungal
3.9-5.7 µg/mL

Target

B. subtilis

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
Active against B. subtilis (MIC 3.9-5.7 ug/ml), M. luteus (MIC 26 ug/ml), S. aureus (MIC 9.7 ug/ml), S. iniae (MIC 4.8 ug/ml), Gram- A.
Evidence 12 Activity

Activity

MIC
Antifungal
26 µg/mL

Target

M. luteus

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Active against B. subtilis (MIC 3.9-5.7 ug/ml), M. luteus (MIC 26 ug/ml), S. aureus (MIC 9.7 ug/ml), S. iniae (MIC 4.8 ug/ml), Gram- A. hydrophila (MIC 25 ug/ml),
Evidence 13 Activity

Activity

MIC
Antifungal
9.7 µg/mL

Target

Staphylococcus aureus

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Active against B. subtilis (MIC 3.9-5.7 ug/ml), M. luteus (MIC 26 ug/ml), S. aureus (MIC 9.7 ug/ml), S. iniae (MIC 4.8 ug/ml), Gram- A. hydrophila (MIC 25 ug/ml), E. coli D31 or ML35p or KC
Evidence 14 Activity

Activity

MIC
Antifungal
4.8 µg/mL

Target

S. iniae

Source & Reference

dbAMP CAFPdb Antifungipept

Other

nst B. subtilis (MIC 3.9-5.7 ug/ml), M. luteus (MIC 26 ug/ml), S. aureus (MIC 9.7 ug/ml), S. iniae (MIC 4.8 ug/ml), Gram- A. hydrophila (MIC 25 ug/ml), E. coli D31 or ML35p or KCTC1116 (MIC 2.7-6.4 ug/ml)
Evidence 15 Activity

Activity

MIC
Antifungal
25 µg/mL

Target

A. hydrophila

Source & Reference

dbAMP CAFPdb Antifungipept

Other

ml), M. luteus (MIC 26 ug/ml), S. aureus (MIC 9.7 ug/ml), S. iniae (MIC 4.8 ug/ml), Gram- A. hydrophila (MIC 25 ug/ml), E. coli D31 or ML35p or KCTC1116 (MIC 2.7-6.4 ug/ml), P. aeruginosa KCTC2004 (MIC 5.6 ug
Evidence 16 Activity

Activity

MIC
Antifungal
2.7-6.4 µg/mL

Target

Escherichia coli D31 or ML35p or KCTC1116

Source & Reference

dbAMP CAFPdb Antifungipept

Other

S. aureus (MIC 9.7 ug/ml), S. iniae (MIC 4.8 ug/ml), Gram- A. hydrophila (MIC 25 ug/ml), E. coli D31 or ML35p or KCTC1116 (MIC 2.7-6.4 ug/ml), P. aeruginosa KCTC2004 (MIC 5.6 ug/ml), S. enterica KCTC2514 (MIC 2.0 ug/ml), S. flexner
Evidence 17 Activity

Activity

MIC
Antifungal
5.6 µg/mL

Target

Pseudomonas aeruginosa KCTC2004

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Gram- A. hydrophila (MIC 25 ug/ml), E. coli D31 or ML35p or KCTC1116 (MIC 2.7-6.4 ug/ml), P. aeruginosa KCTC2004 (MIC 5.6 ug/ml), S. enterica KCTC2514 (MIC 2.0 ug/ml), S. flexneri KCTC2517 (MIC 1.8 ug/ml), S. sonnei KC
Evidence 18 Activity

Activity

MIC
Antifungal
2.0 µg/mL

Target

S. enterica KCTC2514

Source & Reference

dbAMP CAFPdb Antifungipept

Other

oli D31 or ML35p or KCTC1116 (MIC 2.7-6.4 ug/ml), P. aeruginosa KCTC2004 (MIC 5.6 ug/ml), S. enterica KCTC2514 (MIC 2.0 ug/ml), S. flexneri KCTC2517 (MIC 1.8 ug/ml), S. sonnei KCTC2009 (MIC 1.8 ug/ml), V. parahaemoly
Evidence 19 Activity

Activity

MIC
Antifungal
1.8 µg/mL

Target

S. flexneri KCTC2517

Source & Reference

dbAMP CAFPdb Antifungipept

Other

6.4 ug/ml), P. aeruginosa KCTC2004 (MIC 5.6 ug/ml), S. enterica KCTC2514 (MIC 2.0 ug/ml), S. flexneri KCTC2517 (MIC 1.8 ug/ml), S. sonnei KCTC2009 (MIC 1.8 ug/ml), V. parahaemolyticus (MECs, 3.1-12.0 ug/mL), and C. a
Evidence 20 Activity

Activity

MIC
Antifungal
1.8 µg/mL

Target

S. sonnei KCTC2009

Source & Reference

dbAMP CAFPdb Antifungipept

Other

C 5.6 ug/ml), S. enterica KCTC2514 (MIC 2.0 ug/ml), S. flexneri KCTC2517 (MIC 1.8 ug/ml), S. sonnei KCTC2009 (MIC 1.8 ug/ml), V. parahaemolyticus (MECs, 3.1-12.0 ug/mL), and C. albicans (16 ug/ml). It is bacteriost
Evidence 21 Activity

Activity

0% Hemolysis
Toxicity
<100 µg/mL
Hemolytic Cytotoxic
0% Hemolysis | <100 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Antimicrobial function of the GAPDH-related antimicrobial peptide in the skin of skipjack tuna, Katsuwonus pelamis. | Fish Shellfish Immunol | 2014
Evidence 22 Activity

Activity

0% Hemolysis
Toxicity
<100 µg/mL
Hemolytic Cytotoxic
0% Hemolysis | <100 | µg/mL | target cell: Fish erythrocytes

Target

Fish erythrocytes

Source & Reference

NA
DBAASP
Antimicrobial function of the GAPDH-related antimicrobial peptide in the skin of skipjack tuna, Katsuwonus pelamis. | Fish Shellfish Immunol | 2014