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Peptide record

TPDB11330

Antibacterial Toxicity standard
32 amino acids
Basic Information
3D PDB MODEL
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TPDB11330
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 32-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
FKKFFKKLKNSVKKRAKKFFKKPRVIGVSIPF
Physicochemical Analysis
C190H310N50O36
DCEQHMTWY
K
3870.87
12.50
13
0
13
+13
6.18
-0.519
66.88
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
0
0.00
3
Residue Composition
number
1
A
2
R
1
N
0
D
0
C
0
E
0
Q
1
G
0
H
2
I
1
L
11
K
0
M
6
F
2
P
2
S
0
T
0
W
0
Y
3
V
Amino Acid Distribution
A: 1 R: 2 N: 1 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 2 L: 1 K: 11 M: 0 F: 6 P: 2 S: 2 T: 0 W: 0 Y: 0 V: 3
Chemical Descriptors
32
C190H310N50O36
3870.87
12.50
+13
6.18
-0.519
Evidence Records 3 records
Evidence 1 Activity

Activity

0.60% Hemolysis
Toxicity
50 µg/mL
Hemolytic Cytotoxic
0.60% Hemolysis | 50 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Structure-function relationship of king cobra cathelicidin. | Peptides | 2010
Evidence 2 Activity

Activity

1.10% Hemolysis
Toxicity
100 µg/mL
Hemolytic Cytotoxic
1.10% Hemolysis | 100 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Structure-function relationship of king cobra cathelicidin. | Peptides | 2010
Evidence 3 Activity

Activity

5.60% Hemolysis
Toxicity
200 µg/mL
Hemolytic Cytotoxic
5.60% Hemolysis | 200 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Structure-function relationship of king cobra cathelicidin. | Peptides | 2010