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Peptide record

TPDB11329

Antibacterial Antifungal Antiparasitic Toxicity standard
32 amino acids
Basic Information
3D PDB MODEL
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TPDB11329
Antibacterial Antifungal Antiparasitic Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia Antifungipept dbAMP 3.0 ToxinPred 3.0
standard
No
A 32-aa standard natural multi-activity (Antibacterial, Antifungal, Antiparasitic, and other sources) peptide sequence curated from AntiBP3, Peptipedia, Antifungipept, and other sources, with an available 3D structural model.
Sequence
GVFDIIKGAGKQLIARAMGKIAEKVGLNKDGN
Physicochemical Analysis
C146H251N43O42S1
CHPSTWY
G
3312.92
10.38
6
3
14
+3
7.46
-0.047
103.75
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
3
Residue Composition
number
4
A
1
R
2
N
2
D
0
C
1
E
1
Q
6
G
0
H
4
I
2
L
5
K
1
M
1
F
0
P
0
S
0
T
0
W
0
Y
2
V
Amino Acid Distribution
A: 4 R: 1 N: 2 D: 2 C: 0 E: 1 Q: 1 G: 6 H: 0 I: 4 L: 2 K: 5 M: 1 F: 1 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 2
Chemical Descriptors
32
C146H251N43O42S1
3312.92
10.38
+3
7.46
-0.047
Evidence Records 15 records
Evidence 1 Activity

Activity

MIC
Antibacterial
60 µM

Target

Escherichia coli ATCC 25922

Source & Reference

NA

Other

it has leishmanicidal activity (IC50 15.5 uM). Weakly active against E. coli ATCC 25922 (MIC 60 uM), K.pneumoniae ATCC 700603 (MIC 240 uM), S.choleraesuis ATCC 14028 (MIC 240 uM), and S.aur
Evidence 2 Activity

Activity

MIC
Antibacterial
240 µM

Target

K.pneumoniae ATCC 700603

Source & Reference

NA

Other

hmanicidal activity (IC50 15.5 uM). Weakly active against E. coli ATCC 25922 (MIC 60 uM), K.pneumoniae ATCC 700603 (MIC 240 uM), S.choleraesuis ATCC 14028 (MIC 240 uM), and S.aureus ATCC 29313 (MIC 240 uM).
Evidence 3 Activity

Activity

MIC
Antibacterial
240 µM

Target

S.choleraesuis ATCC 14028

Source & Reference

NA

Other

kly active against E. coli ATCC 25922 (MIC 60 uM), K.pneumoniae ATCC 700603 (MIC 240 uM), S.choleraesuis ATCC 14028 (MIC 240 uM), and S.aureus ATCC 29313 (MIC 240 uM).
Evidence 4 Activity

Activity

MIC
Antibacterial
240 µM

Target

S.aureus ATCC 29313

Source & Reference

NA

Other

0 uM), K.pneumoniae ATCC 700603 (MIC 240 uM), S.choleraesuis ATCC 14028 (MIC 240 uM), and S.aureus ATCC 29313 (MIC 240 uM).
Evidence 5 Activity

Activity

MIC
Antifungal
60 µM

Target

Escherichia coli ATCC 25922

Source & Reference

Antifungipept

Other

it has leishmanicidal activity (IC50 15.5 uM). Weakly active against E. coli ATCC 25922 (MIC 60 uM), K.pneumoniae ATCC 700603 (MIC 240 uM), S.choleraesuis ATCC 14028 (MIC 240 uM), and S.aur
Evidence 6 Activity

Activity

MIC
Antifungal
240 µM

Target

K.pneumoniae ATCC 700603

Source & Reference

Antifungipept

Other

hmanicidal activity (IC50 15.5 uM). Weakly active against E. coli ATCC 25922 (MIC 60 uM), K.pneumoniae ATCC 700603 (MIC 240 uM), S.choleraesuis ATCC 14028 (MIC 240 uM), and S.aureus ATCC 29313 (MIC 240 uM).
Evidence 7 Activity

Activity

MIC
Antifungal
240 µM

Target

S.choleraesuis ATCC 14028

Source & Reference

Antifungipept

Other

kly active against E. coli ATCC 25922 (MIC 60 uM), K.pneumoniae ATCC 700603 (MIC 240 uM), S.choleraesuis ATCC 14028 (MIC 240 uM), and S.aureus ATCC 29313 (MIC 240 uM).
Evidence 8 Activity

Activity

MIC
Antifungal
240 µM

Target

S.aureus ATCC 29313

Source & Reference

Antifungipept

Other

0 uM), K.pneumoniae ATCC 700603 (MIC 240 uM), S.choleraesuis ATCC 14028 (MIC 240 uM), and S.aureus ATCC 29313 (MIC 240 uM).
Evidence 9 Activity

Activity

MIC
Antiparasitic
60 µM

Target

Escherichia coli ATCC 25922

Source & Reference

dbAMP 3.0

Other

Source Activity Label Source Definition
Antiparasitic
dbAMP 3.0 classified under the Anti-parasitic function class.
it has leishmanicidal activity (IC50 15.5 uM). Weakly active against E. coli ATCC 25922 (MIC 60 uM), K.pneumoniae ATCC 700603 (MIC 240 uM), S.choleraesuis ATCC 14028 (MIC 240 uM), and S.aur
Evidence 10 Activity

Activity

MIC
Antiparasitic
240 µM

Target

K.pneumoniae ATCC 700603

Source & Reference

dbAMP 3.0

Other

hmanicidal activity (IC50 15.5 uM). Weakly active against E. coli ATCC 25922 (MIC 60 uM), K.pneumoniae ATCC 700603 (MIC 240 uM), S.choleraesuis ATCC 14028 (MIC 240 uM), and S.aureus ATCC 29313 (MIC 240 uM).
Evidence 11 Activity

Activity

MIC
Antiparasitic
240 µM

Target

S.choleraesuis ATCC 14028

Source & Reference

dbAMP 3.0

Other

kly active against E. coli ATCC 25922 (MIC 60 uM), K.pneumoniae ATCC 700603 (MIC 240 uM), S.choleraesuis ATCC 14028 (MIC 240 uM), and S.aureus ATCC 29313 (MIC 240 uM).
Evidence 12 Activity

Activity

MIC
Antiparasitic
240 µM

Target

S.aureus ATCC 29313

Source & Reference

dbAMP 3.0

Other

0 uM), K.pneumoniae ATCC 700603 (MIC 240 uM), S.choleraesuis ATCC 14028 (MIC 240 uM), and S.aureus ATCC 29313 (MIC 240 uM).
Evidence 13 Activity

Activity

0% Hemolysis
Toxicity
200 µg/mL
Hemolytic Cytotoxic
0% Hemolysis | 200 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Characterization and Biological Activities of Ocellatin Peptides from the Skin Secretion of the Frog Leptodactylus pustulatus. | J Nat Prod | 2015
Evidence 14 Activity

Activity

8% Hemolysis
Toxicity
800 µg/mL
Hemolytic Cytotoxic
8% Hemolysis | 800 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Characterization and Biological Activities of Ocellatin Peptides from the Skin Secretion of the Frog Leptodactylus pustulatus. | J Nat Prod | 2015
Evidence 15 Activity

Activity

Toxicity
Cytotoxic
- | NA | target cell: Mouse fibroblasts NIH 3T3

Target

Mouse fibroblasts NIH 3T3

Source & Reference

NA
DBAASP
Characterization and Biological Activities of Ocellatin Peptides from the Skin Secretion of the Frog Leptodactylus pustulatus. | J Nat Prod | 2015