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Peptide record

TPDB11326

Antibacterial Anticancer Antifungal Antiparasitic Hemolysis Toxicity standard
32 amino acids
Basic Information
3D PDB MODEL
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TPDB11326
Antibacterial Anticancer Antifungal Antiparasitic Hemolysis Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia Antifungipept APD_complete APD_hemolytic HemoPI Hemolytic2 PD_Hemolysis ToxinPred 3.0
standard
No
A 32-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
SLGGVISGAKKVAKVAIPIGKAVLPVVAKLVG
Physicochemical Analysis
C142H255N37O35
RNDCEQHMFTWY
V
3040.81
11.12
5
0
18
+5
3.19
1.156
152.19
Mammalian: 1.9 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
2
Residue Composition
number
5
A
0
R
0
N
0
D
0
C
0
E
0
Q
5
G
0
H
3
I
3
L
5
K
0
M
0
F
2
P
2
S
0
T
0
W
0
Y
7
V
Amino Acid Distribution
A: 5 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 5 H: 0 I: 3 L: 3 K: 5 M: 0 F: 0 P: 2 S: 2 T: 0 W: 0 Y: 0 V: 7
Chemical Descriptors
32
C142H255N37O35
3040.81
11.12
+5
3.19
1.156
Evidence Records 4 records
Evidence 1 Activity

Activity

Hemolysis
[Swiss_Prot Entry Q17313]has hemolytic activity

Source & Reference

Hemolytik APD_complete APD_hemolytic PD_Hemolysis
DRAMP4
Eur. J. Biochem. 1996 241:330-337.

Other

Source Activity Label Source Definition
Hemolysis
APD_complete APD-derived hemolytic peptide annotation. APD_hemolytic APD hemolytic peptide annotation. Hemolytik experimentally validated hemolytic peptide annotation.
Evidence 2 Activity

Activity

100% Hemolysis
Toxicity
645 µM
Hemolytic Cytotoxic
100% Hemolysis | 645 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Antibacterial activity and pore-forming properties of ceratotoxins: a mechanism of action based on the barrel stave model. | Biochim Biophys Acta | 2004
Evidence 3 Activity

Activity

Toxicity
Hemolytic
Hemolytic_activity: [Swiss_Prot Entry Q17313]has hemolytic activity

Target

erythrocytes

Source & Reference

NA
DRAMP
Eur. J. Biochem. 1996 241:330-337.
Evidence 4 Hemolysis

Activity

[Swiss_Prot Entry Q17313]has hemolytic activity
Hemolysis

Source & Reference

APD_complete APD_hemolytic HemoPI PD_Hemolysis
Eur. J. Biochem. 1996 241:330-337.
DRAMP4
APD_complete APD_hemolytic PD_Hemolysis

Other

Source Activity Label Source Definition
Hemolysis
APD_complete APD-derived hemolytic peptide annotation. APD_hemolytic APD hemolytic peptide annotation.