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Peptide record

TPDB11325

Antibacterial Antifungal standard
31 amino acids
Basic Information
3D PDB MODEL
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TPDB11325
Antibacterial Antifungal
Anti-infective peptides
AntiBP3 Peptipedia AFP-GFuse Antifungipept CAFPdb DRAMP dbAMP
standard
No
A 31-aa standard-residue multi-activity (Antibacterial and Antifungal) peptide sequence curated from AntiBP3, Peptipedia, AFP-GFuse, and other sources, with an available 3D structural model.
Sequence
DRCSQQCQHHRDPDRKQQCMRECRRHQGRSD
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C147H243N65O50S5
ANILFTWYV
R
3881.25
8.74
11
5
1
+3
6.36
-2.426
0.00
Mammalian: 1.1 hour Yeast: 3 min E.coli: >10 hour
250
0.06
12
Residue Composition
number
0
A
7
R
0
N
4
D
4
C
1
E
6
Q
1
G
3
H
0
I
0
L
1
K
1
M
0
F
1
P
2
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 7 N: 0 D: 4 C: 4 E: 1 Q: 6 G: 1 H: 3 I: 0 L: 0 K: 1 M: 1 F: 0 P: 1 S: 2 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
31 reviewed residue count
C147H243N65O50S5 sequence-only estimate (linear, free termini)
3881.25 sequence-only estimate (linear, free termini)
8.74 sequence-only estimate (linear, free termini)
+3 sequence-only estimate (linear, free termini)
6.36 sequence-only estimate (linear, free termini)
-2.426 sequence-only estimate (linear, free termini)
Evidence Records 2 records
Evidence 1 Activity

Activity

Antibacterial

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
Like EcAMP1, this peptide is active against P. infestans, a protist (not fungus) using potato tuber disks method.
Evidence 2 Activity

Activity

Antifungal

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
Like EcAMP1, this peptide is active against P. infestans, a protist (not fungus) using potato tuber disks method.