Peptide record

TPDB11324

Antibacterial standard
31 amino acids
Basic Information
3D PDB MODEL
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TPDB11324
Antibacterial
Anti-infective peptides
AntiBP3 Peptipedia
standard
No
A 31-aa standard natural antibacterial peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
GLWETIKTTGKSIALNLLDKIKCKIAGGCPP
Physicochemical Analysis
C147H250N38O41S2
RQHMFYV
K
3269.95
9.65
5
2
11
+3
3.96
0.103
107.10
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
5625
172.02
7
Residue Composition
number
2
A
0
R
1
N
1
D
2
C
1
E
0
Q
4
G
0
H
4
I
4
L
5
K
0
M
0
F
2
P
1
S
3
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 2 R: 0 N: 1 D: 1 C: 2 E: 1 Q: 0 G: 4 H: 0 I: 4 L: 4 K: 5 M: 0 F: 0 P: 2 S: 1 T: 3 W: 1 Y: 0 V: 0
Chemical Descriptors
31
C147H250N38O41S2
3269.95
9.65
+3
3.96
0.103
Evidence Records 3 records
Evidence 1 Activity

Activity

MIC
Antibacterial
39 µg/mL

Target

Streptococcus pyogenes

Source & Reference

NA

Other

Active against Gram+ S-aureus ATCC 6538P (MIC >78 ug/ml), S. pyogenes (MIC 39 ug/ml), Gram- P. aeruginosa ATCC 10148 (MIC 20->78/39 ug/ml), E. coli ATCC 9723H (MIC 5-10 ug/ml
Evidence 2 Activity

Activity

MIC
Antibacterial
5-10 µg/mL

Target

Escherichia coli ATCC 9723H

Source & Reference

NA

Other

ug/ml), S. pyogenes (MIC 39 ug/ml), Gram- P. aeruginosa ATCC 10148 (MIC 20->78/39 ug/ml), E. coli ATCC 9723H (MIC 5-10 ug/ml), E. coli ATCC 25922 or MDR (MIC 2-10 ug/ml). Updated 6/2024
Evidence 3 Activity

Activity

MIC
Antibacterial
2-10 µg/mL

Target

Escherichia coli ATCC 25922 or MDR

Source & Reference

NA

Other

ram- P. aeruginosa ATCC 10148 (MIC 20->78/39 ug/ml), E. coli ATCC 9723H (MIC 5-10 ug/ml), E. coli ATCC 25922 or MDR (MIC 2-10 ug/ml). Updated 6/2024