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Peptide record

TPDB11313

Antibacterial Anticancer Antifungal Antiparasitic Toxicity standard
31 amino acids
Basic Information
3D PDB MODEL
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TPDB11313
Antibacterial Anticancer Antifungal Antiparasitic Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia ACP740 _ACP240 AntiCP 2.0 iACP-DRLF Antifungipept CAFPdb dbAMP 3.0 ToxinPred 3.0
standard
No
A 31-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
AMWKDVLKKIGTVALHAGKAALGAVADTISQ
Physicochemical Analysis
C142H239N39O40S1
RNCEFPY
A
3164.76
10.16
5
2
17
+2
3.04
0.448
113.55
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
5500
173.79
4
Residue Composition
number
7
A
0
R
0
N
2
D
0
C
0
E
1
Q
3
G
1
H
2
I
3
L
4
K
1
M
0
F
0
P
1
S
2
T
1
W
0
Y
3
V
Amino Acid Distribution
A: 7 R: 0 N: 0 D: 2 C: 0 E: 0 Q: 1 G: 3 H: 1 I: 2 L: 3 K: 4 M: 1 F: 0 P: 0 S: 1 T: 2 W: 1 Y: 0 V: 3
Chemical Descriptors
31
C142H239N39O40S1
3164.76
10.16
+2
3.04
0.448
Evidence Records 1 records
Evidence 1 Activity

Activity

100% Hemolysis
Toxicity
>250 µM
Hemolytic Cytotoxic
100% Hemolysis | >250 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
The dermaseptin superfamily: a gene-based combinatorial library of antimicrobial peptides. | Biochim Biophys Acta | 2009